AutismKB 2.0

Annotation Detail for KLF10


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Basic Information Top
Gene Symbol:KLF10 ( EGRA,TIEG,TIEG1 )
Gene Full Name: Kruppel-like factor 10
Band: 8q22.3
Quick LinksEntrez ID:7071; OMIM: 601878; Uniprot ID:KLF10_HUMAN; ENSEMBL ID: ENSG00000155090; HGNC ID: 11810
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst4 / 6231964
fetus27 / 56401247
neonate1 / 3109732
infant0 / 236200 
juvenile6 / 55556107
adult89 / 193912145
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor2 / 3436658
chondrosarcoma6 / 8282372
colorectal tumor2 / 11424617
esophageal tumor1 / 1729057
gastrointestinal tumor12 / 119369100
germ cell tumor11 / 26384541
glioma2 / 10688318
head and neck tumor8 / 13630258
kidney tumor1 / 6895914
leukemia3 / 9584231
liver tumor6 / 9635962
lung tumor3 / 10312729
lymphoma6 / 7175583
non-neoplasia3 / 9725030
normal159 / 336030747
ovarian tumor3 / 7668239
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer4 / 10268038
retinoblastoma3 / 4635664
skin tumor5 / 12494940
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites4 / 4001599
bladder1 / 2975733
blood6 / 12347848
bone2 / 7165527
bone marrow2 / 4880140
brain39 / 110098935
cervix2 / 4817141
connective tissue10 / 14925566
ear1 / 1621261
embryonic tissue10 / 21572246
esophagus1 / 2020949
eye5 / 21105423
heart2 / 8962622
intestine12 / 23447251
kidney3 / 21177714
larynx0 / 241450 
liver11 / 20774352
lung19 / 33697456
lymph0 / 442700 
lymph node12 / 91610130
mammary gland6 / 15327139
mouth9 / 67052134
muscle10 / 10771592
nerve2 / 15768126
ovary3 / 10205129
pancreas15 / 21481269
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta14 / 28082549
prostate7 / 18934536
salivary gland0 / 201550 
skin15 / 21057471
spleen5 / 5395292
stomach9 / 9661993
testis21 / 33044263
thymus2 / 8113124
thyroid1 / 4747321
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus10 / 23287842
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202393_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts71.2
Adipocyte21.5
AdrenalCortex26.3
Adrenalgland45.4
Amygdala27.85
Appendix53.55
AtrioventricularNode12.1
BDCA4+_DentriticCells293.15
Bonemarrow38.05
BronchialEpithelialCells108.15
CD105+_Endothelial98.75
CD14+_Monocytes467.2
CD19+_BCells(neg._sel.)32.7
CD33+_Myeloid708.8
CD34+190.95
CD4+_Tcells17.15
CD56+_NKCells32.85
CD71+_EarlyErythroid40.3
CD8+_Tcells19.9
CardiacMyocytes61.05
Caudatenucleus9.85
Cerebellum11.7
CerebellumPeduncles12.45
CiliaryGanglion22.65
CingulateCortex17.85
Colorectaladenocarcinoma135.95
DorsalRootGanglion19.4
FetalThyroid33
Fetalbrain48.65
Fetalliver20.7
Fetallung88.5
GlobusPallidus15.35
Heart52.5
Hypothalamus20.7
Kidney30.6
Leukemia_chronicMyelogenousK-56289.55
Leukemia_promyelocytic-HL-6035
Leukemialymphoblastic(MOLT-4)21.45
Liver98.55
Lung319.35
Lymphnode24.2
Lymphoma_burkitts(Daudi)30.1
Lymphoma_burkitts(Raji)93.05
MedullaOblongata15.3
OccipitalLobe23.35
OlfactoryBulb19.1
Ovary16.25
Pancreas51.4
PancreaticIslet130.5
ParietalLobe17.65
Pituitary36.7
Placenta372.95
Pons20
PrefrontalCortex16.5
Prostate48.25
Salivarygland21.65
SkeletalMuscle31.95
Skin52.95
SmoothMuscle103.95
Spinalcord17.85
SubthalamicNucleus20.65
SuperiorCervicalGanglion30.45
TemporalLobe18.9
Testis98.05
TestisGermCell41.7
TestisIntersitial40.7
TestisLeydigCell24.35
TestisSeminiferousTubule23.15
Thalamus17.3
Thymus34.65
Thyroid111.7
Tongue38.5
Tonsil21.75
Trachea72.45
TrigeminalGanglion30.55
Uterus116.2
UterusCorpus31.3
WholeBlood119.3
Wholebrain34.6
colon385
pineal_day17.04
pineal_night18.24
retina106.75
small_intestine460.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13901_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.31 ± 0.86
Basal Forebrain2.35 ± 0.3
Basal Part of Pons2.38 ± 0.36
Cerebellar Cortex2.28 ± 0.54
Cerebellar Nuclei2.68 ± 0.56
Claustrum3.4 ± 0.81
Epithalamus2.59 ± 0.71
Frontal Lobe2.76 ± 0.68
Globus Pallidus2.46 ± 0.62
Hypothalamus2.49 ± 0.75
Insula2.64 ± 0.69
Limbic Lobe2.9 ± 0.66
Mesencephalon2.86 ± 0.75
Myelencephalon2.75 ± 0.68
Occipital Lobe2.94 ± 0.94
Parietal Lobe2.71 ± 0.78
Pontine Tegmentum2.78 ± 0.69
Striatum2.66 ± 0.84
Subthalamus2.85 ± 0.81
Temporal Lobe2.91 ± 0.65
Thalamus2.49 ± 0.72
White Matter2.21 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Klf10CBCerebellum2.06
2.29
Klf10CTXCerebral cortex95.48
83.27
Klf10HIPHippocampal region25.11
43.61
Klf10HPFHippocampal formation27.28
37.04
Klf10HYHypothalamus1.07
0.86
Klf10LSXLateral septal complex5.1
4.53
Klf10MBMidbrain1.47
1.6
Klf10MYMedulla1.4
1.72
Klf10OLFOlfactory bulb45.32
39.9
Klf10PPons1.17
1.37
Klf10PALPallidum1.06
0.82
Klf10RHPRetrohippocampal region29.86
28.64
Klf10sAMYStriatum-like amygdalar nuclei14.81
13.93
Klf10STRStriatum12.23
9.32
Klf10STRdStriatum dorsal region12.88
9.58
Klf10STRvStriatum ventral region10.87
6.92
Klf10THThalamus1.69
1.85
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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