AutismKB 2.0

Annotation Detail for TIAM1


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Basic Information Top
Gene Symbol:TIAM1 ( FLJ36302 )
Gene Full Name: T-cell lymphoma invasion and metastasis 1
Band: 21q22.11
Quick LinksEntrez ID:7074; OMIM: 600687; Uniprot ID:TIAM1_HUMAN; ENSEMBL ID: ENSG00000156299; HGNC ID: 11805
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst0 / 623190 
fetus26 / 56401246
neonate1 / 3109732
infant0 / 236200 
juvenile4 / 5555671
adult45 / 193912123
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor10 / 26384537
glioma10 / 10688393
head and neck tumor6 / 13630244
kidney tumor1 / 6895914
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma4 / 7175555
non-neoplasia7 / 9725071
normal130 / 336030738
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone1 / 7165513
bone marrow1 / 4880120
brain61 / 110098955
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye6 / 21105428
heart4 / 8962644
intestine3 / 23447212
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung9 / 33697426
lymph0 / 442700 
lymph node1 / 9161010
mammary gland1 / 1532716
mouth1 / 6705214
muscle0 / 1077150 
nerve4 / 15768253
ovary0 / 1020510 
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland2 / 16585120
placenta7 / 28082524
prostate1 / 1893455
salivary gland0 / 201550 
skin7 / 21057433
spleen1 / 5395218
stomach0 / 966190 
testis3 / 3304429
thymus4 / 8113149
thyroid3 / 4747363
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206409_at
Cell line Expression level Expression bar
721_B_lymphoblasts25.4
Adipocyte28.9
AdrenalCortex35
Adrenalgland23.35
Amygdala36.9
Appendix26.75
AtrioventricularNode28.9
BDCA4+_DentriticCells18.85
Bonemarrow30.35
BronchialEpithelialCells26.05
CD105+_Endothelial23.35
CD14+_Monocytes11.45
CD19+_BCells(neg._sel.)17.9
CD33+_Myeloid30.65
CD34+27.55
CD4+_Tcells34.45
CD56+_NKCells21.1
CD71+_EarlyErythroid24.9
CD8+_Tcells21
CardiacMyocytes36.2
Caudatenucleus24.2
Cerebellum171.35
CerebellumPeduncles262.85
CiliaryGanglion19.6
CingulateCortex30.4
Colorectaladenocarcinoma38.5
DorsalRootGanglion21.95
FetalThyroid26.15
Fetalbrain36.4
Fetalliver43.95
Fetallung21.75
GlobusPallidus25.5
Heart54.3
Hypothalamus28.9
Kidney23.4
Leukemia_chronicMyelogenousK-56222.75
Leukemia_promyelocytic-HL-6023.05
Leukemialymphoblastic(MOLT-4)21.35
Liver54.05
Lung37.35
Lymphnode24.3
Lymphoma_burkitts(Daudi)34.8
Lymphoma_burkitts(Raji)39.3
MedullaOblongata30.6
OccipitalLobe24.05
OlfactoryBulb22.2
Ovary18.85
Pancreas21.5
PancreaticIslet30.4
ParietalLobe44.15
Pituitary32.05
Placenta25.45
Pons32.95
PrefrontalCortex31.85
Prostate30.95
Salivarygland21.6
SkeletalMuscle59.85
Skin26.65
SmoothMuscle25.05
Spinalcord31.75
SubthalamicNucleus25.15
SuperiorCervicalGanglion32.5
TemporalLobe31.9
Testis24.3
TestisGermCell25.35
TestisIntersitial26
TestisLeydigCell27.2
TestisSeminiferousTubule25.5
Thalamus28.9
Thymus26.1
Thyroid32.65
Tongue26.25
Tonsil26.25
Trachea22.45
TrigeminalGanglion26.4
Uterus21.8
UterusCorpus24.8
WholeBlood25.95
Wholebrain39.75
colon26.4
pineal_day31.66
pineal_night31.16
retina34.75
small_intestine22.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P138666
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.46 ± 0.28
Basal Forebrain5.44 ± 0.32
Basal Part of Pons4.53 ± 0.6
Cerebellar Cortex6.31 ± 0.54
Cerebellar Nuclei5.16 ± 0.66
Claustrum3.99 ± 0.94
Epithalamus5.26 ± 0.61
Frontal Lobe5.03 ± 0.54
Globus Pallidus4.67 ± 0.37
Hypothalamus4.74 ± 0.31
Insula5.36 ± 0.44
Limbic Lobe5.31 ± 0.86
Mesencephalon5.04 ± 0.7
Myelencephalon5.32 ± 0.63
Occipital Lobe6.29 ± 0.61
Parietal Lobe5.58 ± 0.78
Pontine Tegmentum5.62 ± 0.74
Striatum5.21 ± 0.69
Subthalamus4.15 ± 0.6
Temporal Lobe5.45 ± 0.59
Thalamus5.74 ± 0.49
White Matter4.63 ± 0.22
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tiam1CBCerebellum100
100
Tiam1CTXCerebral cortex59.4
47.19
Tiam1HIPHippocampal region70.58
82.97
Tiam1HPFHippocampal formation76.47
80.1
Tiam1HYHypothalamus10.69
7.89
Tiam1LSXLateral septal complex67.07
62.26
Tiam1MBMidbrain11.1
10.47
Tiam1MYMedulla19.11
19.08
Tiam1OLFOlfactory bulb100
100
Tiam1PPons12.09
11.7
Tiam1PALPallidum29.03
26.56
Tiam1RHPRetrohippocampal region87.88
77.7
Tiam1sAMYStriatum-like amygdalar nuclei63.23
51.3
Tiam1STRStriatum57.8
51.05
Tiam1STRdStriatum dorsal region42.36
35.27
Tiam1STRvStriatum ventral region96.71
85.94
Tiam1THThalamus83.04
89.26
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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