AutismKB 2.0

Annotation Detail for TIMP1


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Basic Information Top
Gene Symbol:TIMP1 ( CLGI,EPA,EPO,FLJ90373,HCI,TIMP )
Gene Full Name: TIMP metallopeptidase inhibitor 1
Band: Xp11.3
Quick LinksEntrez ID:7076; OMIM: 305370; Uniprot ID:TIMP1_HUMAN; ENSEMBL ID: ENSG00000102265; HGNC ID: 11820
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst5 / 6231980
fetus67 / 564012118
neonate11 / 31097353
infant9 / 23620381
juvenile1 / 5555617
adult500 / 1939121257
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma0 / 174750 
breast (mammary gland) tumor30 / 94178318
cervical tumor4 / 34366116
chondrosarcoma77 / 82823929
colorectal tumor19 / 114246166
esophageal tumor2 / 17290115
gastrointestinal tumor24 / 119369201
germ cell tumor22 / 26384583
glioma16 / 106883149
head and neck tumor16 / 136302117
kidney tumor14 / 68959203
leukemia3 / 9584231
liver tumor11 / 96359114
lung tumor118 / 1031271144
lymphoma8 / 71755111
non-neoplasia13 / 97250133
normal567 / 3360307168
ovarian tumor60 / 76682782
pancreatic tumor80 / 104616764
primitive neuroectodermal tumor of the CNS16 / 125680127
prostate cancer11 / 102680107
retinoblastoma0 / 463560 
skin tumor22 / 124949176
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor12 / 90257132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue6 / 13106457
adrenal gland9 / 33197271
ascites10 / 40015249
bladder1 / 2975733
blood7 / 12347856
bone50 / 71655697
bone marrow18 / 48801368
brain53 / 110098948
cervix8 / 48171166
connective tissue56 / 149255375
ear3 / 16212185
embryonic tissue13 / 21572260
esophagus2 / 2020998
eye45 / 211054213
heart16 / 89626178
intestine36 / 234472153
kidney20 / 21177794
larynx23 / 24145952
liver29 / 207743139
lung225 / 336974667
lymph0 / 442700 
lymph node7 / 9161076
mammary gland51 / 153271332
mouth5 / 6705274
muscle7 / 10771564
nerve3 / 15768190
ovary66 / 102051646
pancreas106 / 214812493
parathyroid4 / 20539194
pharynx7 / 41328169
pituitary gland11 / 16585663
placenta43 / 280825153
prostate30 / 189345158
salivary gland2 / 2015599
skin64 / 210574303
spleen3 / 5395255
stomach15 / 96619155
testis29 / 33044287
thymus1 / 8113112
thyroid7 / 47473147
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord11 / 13680804
uterus30 / 232878128
vascular11 / 51780212
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201666_at
Cell line Expression level Expression bar
721_B_lymphoblasts215.8
Adipocyte3322.45
AdrenalCortex758.95
Adrenalgland565.45
Amygdala17.6
Appendix204.35
AtrioventricularNode206.1
BDCA4+_DentriticCells110.2
Bonemarrow70.9
BronchialEpithelialCells569.95
CD105+_Endothelial14.1
CD14+_Monocytes544.7
CD19+_BCells(neg._sel.)6.85
CD33+_Myeloid393.95
CD34+96.35
CD4+_Tcells68.5
CD56+_NKCells173.05
CD71+_EarlyErythroid2.6
CD8+_Tcells27.45
CardiacMyocytes3068.25
Caudatenucleus12.75
Cerebellum25.75
CerebellumPeduncles34.1
CiliaryGanglion152.95
CingulateCortex5.5
Colorectaladenocarcinoma298.5
DorsalRootGanglion59.65
FetalThyroid790.15
Fetalbrain22.85
Fetalliver25.45
Fetallung1468
GlobusPallidus3.5
Heart732.15
Hypothalamus38.3
Kidney34.95
Leukemia_chronicMyelogenousK-562728.5
Leukemia_promyelocytic-HL-603.9
Leukemialymphoblastic(MOLT-4)4.35
Liver678.2
Lung933.25
Lymphnode303.9
Lymphoma_burkitts(Daudi)4.9
Lymphoma_burkitts(Raji)5.6
MedullaOblongata7.5
OccipitalLobe7.4
OlfactoryBulb307.45
Ovary1244.95
Pancreas492.35
PancreaticIslet1266.8
ParietalLobe12.95
Pituitary387.2
Placenta1038.45
Pons83.55
PrefrontalCortex41.15
Prostate851.55
Salivarygland52
SkeletalMuscle52.2
Skin18.5
SmoothMuscle3630.3
Spinalcord136.75
SubthalamicNucleus3.85
SuperiorCervicalGanglion59.15
TemporalLobe11.35
Testis450.5
TestisGermCell939.95
TestisIntersitial119.6
TestisLeydigCell230.3
TestisSeminiferousTubule412.1
Thalamus14.95
Thymus142.5
Thyroid185.95
Tongue34.95
Tonsil120.3
Trachea356.5
TrigeminalGanglion254.6
Uterus529.25
UterusCorpus1652.4
WholeBlood413.75
Wholebrain8.65
colon76.3
pineal_day1722.34
pineal_night1972.8
retina841.2
small_intestine181.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15142_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.64 ± 0.78
Basal Forebrain5.93 ± 0.29
Basal Part of Pons5.08 ± 0.59
Cerebellar Cortex5.96 ± 0.43
Cerebellar Nuclei5.6 ± 0.45
Claustrum5.67 ± 0.54
Epithalamus6.52 ± 0.53
Frontal Lobe5.46 ± 0.57
Globus Pallidus6.75 ± 0.68
Hypothalamus5.84 ± 0.51
Insula5.68 ± 0.38
Limbic Lobe5.47 ± 0.65
Mesencephalon5.72 ± 0.53
Myelencephalon5.66 ± 0.57
Occipital Lobe5.14 ± 0.44
Parietal Lobe5.3 ± 0.65
Pontine Tegmentum5.59 ± 0.68
Striatum5.83 ± 0.61
Subthalamus5.22 ± 0.71
Temporal Lobe5.53 ± 0.58
Thalamus5.47 ± 0.51
White Matter5.38 ± 0.75
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00009981 11 193 203 EPGLCTWQSLR Peptide Atlas
TIMP1_HUMAN_192 11 192 202 EPGLCTWQSLR PRIDE
TIMP1_HUMAN_70 12 70 81 GFQALGDAADIR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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