AutismKB 2.0

Annotation Detail for TMPO


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TMPO ( CMD1T,LAP2,LEMD4,MGC61508,PRO0868,TP )
Gene Full Name: thymopoietin
Band: 12q23.1
Quick LinksEntrez ID:7112; OMIM: 188380; Uniprot ID:LAP2A_HUMAN; ENSEMBL ID: ENSG00000120802; HGNC ID: 11875
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body15 / 70761211
blastocyst13 / 62319208
fetus80 / 564012141
neonate1 / 3109732
infant6 / 23620254
juvenile9 / 55556161
adult134 / 193912169
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma2 / 17475114
breast (mammary gland) tumor13 / 94178138
cervical tumor5 / 34366145
chondrosarcoma12 / 82823144
colorectal tumor11 / 11424696
esophageal tumor1 / 1729057
gastrointestinal tumor11 / 11936992
germ cell tumor48 / 263845181
glioma17 / 106883159
head and neck tumor6 / 13630244
kidney tumor3 / 6895943
leukemia17 / 95842177
liver tumor12 / 96359124
lung tumor4 / 10312738
lymphoma9 / 71755125
non-neoplasia1 / 9725010
normal296 / 336030788
ovarian tumor4 / 7668252
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS15 / 125680119
prostate cancer4 / 10268038
retinoblastoma9 / 46356194
skin tumor11 / 12494988
soft tissue/muscle tissue tumor12 / 12519195
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites5 / 40015124
bladder8 / 29757268
blood9 / 12347872
bone14 / 71655195
bone marrow13 / 48801266
brain73 / 110098966
cervix7 / 48171145
connective tissue6 / 14925540
ear8 / 16212493
embryonic tissue36 / 215722166
esophagus1 / 2020949
eye22 / 211054104
heart7 / 8962678
intestine19 / 23447281
kidney14 / 21177766
larynx0 / 241450 
liver17 / 20774381
lung18 / 33697453
lymph3 / 4427067
lymph node33 / 91610360
mammary gland17 / 153271110
mouth4 / 6705259
muscle4 / 10771537
nerve0 / 157680 
ovary7 / 10205168
pancreas17 / 21481279
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta18 / 28082564
prostate8 / 18934542
salivary gland3 / 20155148
skin14 / 21057466
spleen1 / 5395218
stomach3 / 9661931
testis55 / 330442166
thymus16 / 81131197
thyroid4 / 4747384
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus23 / 23287898
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209754_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts96.05
Adipocyte7.25
AdrenalCortex8.3
Adrenalgland7
Amygdala8.2
Appendix10.4
AtrioventricularNode6.2
BDCA4+_DentriticCells26.25
Bonemarrow14.85
BronchialEpithelialCells6.9
CD105+_Endothelial47.2
CD14+_Monocytes10.75
CD19+_BCells(neg._sel.)19.35
CD33+_Myeloid24.95
CD34+92.65
CD4+_Tcells20.5
CD56+_NKCells32.45
CD71+_EarlyErythroid142.1
CD8+_Tcells14.9
CardiacMyocytes10.75
Caudatenucleus6.9
Cerebellum6.35
CerebellumPeduncles9.5
CiliaryGanglion7.6
CingulateCortex8.3
Colorectaladenocarcinoma9.1
DorsalRootGanglion6.55
FetalThyroid7.7
Fetalbrain7.45
Fetalliver37.85
Fetallung5.95
GlobusPallidus6.2
Heart10.4
Hypothalamus7.75
Kidney7.35
Leukemia_chronicMyelogenousK-5627.15
Leukemia_promyelocytic-HL-6017.95
Leukemialymphoblastic(MOLT-4)52.55
Liver12.65
Lung8
Lymphnode6.5
Lymphoma_burkitts(Daudi)10.55
Lymphoma_burkitts(Raji)12.25
MedullaOblongata6.65
OccipitalLobe6.5
OlfactoryBulb5.65
Ovary5.2
Pancreas6.35
PancreaticIslet8.25
ParietalLobe8.4
Pituitary9.05
Placenta6.9
Pons8.3
PrefrontalCortex8.75
Prostate8.7
Salivarygland6.7
SkeletalMuscle16.3
Skin6.95
SmoothMuscle8.35
Spinalcord7.6
SubthalamicNucleus7.25
SuperiorCervicalGanglion13.55
TemporalLobe7.45
Testis6.2
TestisGermCell5.5
TestisIntersitial6.6
TestisLeydigCell8.1
TestisSeminiferousTubule6.5
Thalamus7.9
Thymus36.15
Thyroid8.2
Tongue9.3
Tonsil8.15
Trachea5.95
TrigeminalGanglion8.9
Uterus6.1
UterusCorpus8.35
WholeBlood11.5
Wholebrain5.9
colon48.2
pineal_day9.04
pineal_night9
retina8.55
small_intestine39.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P325040
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.54 ± 0.9
Basal Forebrain3.2 ± 0.41
Basal Part of Pons3 ± 0.44
Cerebellar Cortex4.01 ± 0.37
Cerebellar Nuclei3.8 ± 0.67
Claustrum3.79 ± 0.87
Epithalamus3.84 ± 0.45
Frontal Lobe3.42 ± 0.76
Globus Pallidus3.11 ± 0.58
Hypothalamus3.42 ± 0.29
Insula2.55 ± 0.79
Limbic Lobe3.25 ± 0.71
Mesencephalon3.58 ± 0.66
Myelencephalon3.41 ± 0.62
Occipital Lobe3.77 ± 0.57
Parietal Lobe3.56 ± 0.65
Pontine Tegmentum3.51 ± 0.76
Striatum2.7 ± 0.61
Subthalamus3.47 ± 0.72
Temporal Lobe3.42 ± 0.72
Thalamus3.39 ± 0.64
White Matter4.12 ± 0.45
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
LAP2A_HUMAN_1 32 1 32 PEFLEDPSVLTKDKLKSELVANNVTLPAGEQR PRIDE
LAP2A_HUMAN_130 9 130 138 PGPIVGTTR PRIDE
LAP2A_HUMAN_2 32 2 33 PEFLEDPSVLTKDKLKSELVANNVTLPAGEQR PRIDE
LAP2A_HUMAN_440 22 440 461 DSGSFVAFQNIPGSELMSSFAK PRIDE
LAP2A_HUMAN_511 14 511 524 QLPSLACKYPVSSR PRIDE
LAP2B_HUMAN_126 13 126 138 YGVNPGPIVGTTR PRIDE
LAP2B_HUMAN_269 28 269 296 IDGPVISESTPIAETIMASSNESLVVNR PRIDE
LAP2B_HUMAN_368 13 368 380 GAAGRPLELSDFR PRIDE
LAP2B_HUMAN_373 8 373 380 PLELSDFR PRIDE
PAp00001861 14 35 48 DVYVQLYLQHLTAR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved