AutismKB 2.0

Annotation Detail for TMPRSS2


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Basic Information Top
Gene Symbol:TMPRSS2 ( FLJ41954,PP9284,PRSS10 )
Gene Full Name: transmembrane protease, serine 2
Band: 21q22.3
Quick LinksEntrez ID:7113; OMIM: 602060; Uniprot ID:TMPS2_HUMAN; ENSEMBL ID: ENSG00000184012; HGNC ID: 11876
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus6 / 56401210
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult93 / 193912147
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma5 / 17475286
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor14 / 114246122
esophageal tumor0 / 172900 
gastrointestinal tumor12 / 119369100
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor8 / 13630258
kidney tumor0 / 689590 
leukemia4 / 9584241
liver tumor2 / 9635920
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal103 / 336030730
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer50 / 102680486
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites3 / 4001574
bladder11 / 29757369
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine30 / 234472127
kidney12 / 21177756
larynx0 / 241450 
liver3 / 20774314
lung9 / 33697426
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth8 / 67052119
muscle3 / 10771527
nerve2 / 15768126
ovary0 / 1020510 
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate111 / 189345586
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach13 / 96619134
testis2 / 3304426
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205102_at
Cell line Expression level Expression bar
721_B_lymphoblasts12.2
Adipocyte10.2
AdrenalCortex11.2
Adrenalgland8.8
Amygdala10.65
Appendix10.45
AtrioventricularNode8.95
BDCA4+_DentriticCells8.7
Bonemarrow10.2
BronchialEpithelialCells10.25
CD105+_Endothelial10.05
CD14+_Monocytes6.95
CD19+_BCells(neg._sel.)9.9
CD33+_Myeloid12.05
CD34+12.75
CD4+_Tcells10.25
CD56+_NKCells11.2
CD71+_EarlyErythroid9.65
CD8+_Tcells6.35
CardiacMyocytes12.7
Caudatenucleus9.35
Cerebellum8.4
CerebellumPeduncles11.9
CiliaryGanglion7.6
CingulateCortex10.65
Colorectaladenocarcinoma9.45
DorsalRootGanglion7.85
FetalThyroid10.15
Fetalbrain10.45
Fetalliver8.85
Fetallung8.75
GlobusPallidus7.55
Heart13.3
Hypothalamus11.3
Kidney9.1
Leukemia_chronicMyelogenousK-5629.95
Leukemia_promyelocytic-HL-609.2
Leukemialymphoblastic(MOLT-4)9.1
Liver13.5
Lung11.5
Lymphnode9
Lymphoma_burkitts(Daudi)13.2
Lymphoma_burkitts(Raji)14.7
MedullaOblongata9.55
OccipitalLobe9.2
OlfactoryBulb8.2
Ovary6.75
Pancreas8.4
PancreaticIslet13.6
ParietalLobe11.4
Pituitary12.35
Placenta10
Pons9.85
PrefrontalCortex12.45
Prostate35.55
Salivarygland8.8
SkeletalMuscle13.15
Skin7.95
SmoothMuscle11.75
Spinalcord11.5
SubthalamicNucleus9.45
SuperiorCervicalGanglion12.25
TemporalLobe9.5
Testis8.85
TestisGermCell8.5
TestisIntersitial8.65
TestisLeydigCell10.55
TestisSeminiferousTubule8.75
Thalamus13.5
Thymus8.2
Thyroid12.6
Tongue11.2
Tonsil10.1
Trachea8.7
TrigeminalGanglion10.6
Uterus8.15
UterusCorpus12
WholeBlood11.05
Wholebrain8.75
colon11.05
pineal_day12.2
pineal_night12.3
retina11.975
small_intestine10
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14042_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala1.92 ± 1.06
Basal Forebrain1.42 ± 0.2
Basal Part of Pons1.19 ± 0.42
Cerebellar Cortex1.25 ± 0.68
Cerebellar Nuclei1.72 ± 0.73
Claustrum2.26 ± 0.81
Epithalamus1.25 ± 0.65
Frontal Lobe1.3 ± 0.62
Globus Pallidus2.2 ± 0.5
Hypothalamus1.59 ± 0.73
Insula1.4 ± 0.56
Limbic Lobe1.48 ± 0.67
Mesencephalon1.68 ± 0.78
Myelencephalon1.5 ± 0.68
Occipital Lobe1.52 ± 0.62
Parietal Lobe1.52 ± 0.78
Pontine Tegmentum1.5 ± 0.66
Striatum1.64 ± 0.59
Subthalamus1.56 ± 0.61
Temporal Lobe1.38 ± 0.68
Thalamus1.44 ± 0.61
White Matter1.94 ± 0.18
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00041239 11 224 234 KLYHSDACSSK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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