AutismKB 2.0

Annotation Detail for TNFAIP1


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Basic Information Top
Gene Symbol:TNFAIP1 ( B12,B61,EDP1,MGC2317,hBACURD2 )
Gene Full Name: tumor necrosis factor, alpha-induced protein 1 (endothelial)
Band: 17q11.2
Quick LinksEntrez ID:7126; OMIM: 191161; Uniprot ID:BACD2_HUMAN; ENSEMBL ID: ENSG00000109079; HGNC ID: 11894
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body14 / 70761197
blastocyst3 / 6231948
fetus58 / 564012102
neonate5 / 31097160
infant3 / 23620127
juvenile0 / 555560 
adult244 / 1939121125
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor14 / 94178148
cervical tumor3 / 3436687
chondrosarcoma8 / 8282396
colorectal tumor14 / 114246122
esophageal tumor1 / 1729057
gastrointestinal tumor22 / 119369184
germ cell tumor43 / 263845162
glioma9 / 10688384
head and neck tumor22 / 136302161
kidney tumor1 / 6895914
leukemia3 / 9584231
liver tumor19 / 96359197
lung tumor21 / 103127203
lymphoma7 / 7175597
non-neoplasia6 / 9725061
normal407 / 3360307121
ovarian tumor6 / 7668278
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer9 / 10268087
retinoblastoma2 / 4635643
skin tumor26 / 124949208
soft tissue/muscle tissue tumor20 / 125191159
uterine tumor15 / 90257166
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites3 / 4001574
bladder1 / 2975733
blood7 / 12347856
bone5 / 7165569
bone marrow1 / 4880120
brain168 / 1100989152
cervix4 / 4817183
connective tissue12 / 14925580
ear1 / 1621261
embryonic tissue20 / 21572292
esophagus1 / 2020949
eye20 / 21105494
heart6 / 8962666
intestine25 / 234472106
kidney9 / 21177742
larynx5 / 24145207
liver27 / 207743129
lung43 / 336974127
lymph4 / 4427090
lymph node13 / 91610141
mammary gland28 / 153271182
mouth6 / 6705289
muscle28 / 107715259
nerve0 / 157680 
ovary7 / 10205168
pancreas15 / 21481269
parathyroid1 / 2053948
pharynx3 / 4132872
pituitary gland1 / 1658560
placenta83 / 280825295
prostate12 / 18934563
salivary gland8 / 20155396
skin35 / 210574166
spleen7 / 53952129
stomach9 / 9661993
testis37 / 330442111
thymus9 / 81131110
thyroid4 / 4747384
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord7 / 13680511
uterus33 / 232878141
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201207_at
Cell line Expression level Expression bar
721_B_lymphoblasts11.8
Adipocyte12.4
AdrenalCortex18.1
Adrenalgland20.5
Amygdala24.5
Appendix9.6
AtrioventricularNode7.5
BDCA4+_DentriticCells7.65
Bonemarrow8.9
BronchialEpithelialCells45.3
CD105+_Endothelial5.4
CD14+_Monocytes5.75
CD19+_BCells(neg._sel.)6.6
CD33+_Myeloid5
CD34+6.7
CD4+_Tcells5.8
CD56+_NKCells7.35
CD71+_EarlyErythroid4.6
CD8+_Tcells6.15
CardiacMyocytes22.05
Caudatenucleus13.35
Cerebellum24
CerebellumPeduncles18.45
CiliaryGanglion8.5
CingulateCortex19.45
Colorectaladenocarcinoma22.05
DorsalRootGanglion6.35
FetalThyroid12.1
Fetalbrain31.5
Fetalliver11.35
Fetallung34.3
GlobusPallidus10.45
Heart23.85
Hypothalamus16.75
Kidney12.95
Leukemia_chronicMyelogenousK-5628.8
Leukemia_promyelocytic-HL-608.1
Leukemialymphoblastic(MOLT-4)8.85
Liver47.2
Lung30.35
Lymphnode11.2
Lymphoma_burkitts(Daudi)7.6
Lymphoma_burkitts(Raji)11.6
MedullaOblongata17.95
OccipitalLobe15.25
OlfactoryBulb10.9
Ovary7.95
Pancreas12.4
PancreaticIslet19.8
ParietalLobe14
Pituitary11.2
Placenta84.25
Pons12.4
PrefrontalCortex19.1
Prostate12.6
Salivarygland8.05
SkeletalMuscle14
Skin7.4
SmoothMuscle51.85
Spinalcord18.65
SubthalamicNucleus10.55
SuperiorCervicalGanglion13.75
TemporalLobe11.9
Testis18.3
TestisGermCell16.3
TestisIntersitial6.4
TestisLeydigCell9.95
TestisSeminiferousTubule10.25
Thalamus15.55
Thymus16.5
Thyroid16.9
Tongue12.15
Tonsil12.3
Trachea10.45
TrigeminalGanglion11.1
Uterus14.35
UterusCorpus11.1
WholeBlood9.1
Wholebrain35.85
colon12
pineal_day60.08
pineal_night81.34
retina42.075
small_intestine12.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14763_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.7 ± 0.68
Basal Forebrain5.36 ± 0.26
Basal Part of Pons5.55 ± 0.42
Cerebellar Cortex5.58 ± 0.26
Cerebellar Nuclei5.46 ± 0.33
Claustrum6.31 ± 0.47
Epithalamus5.18 ± 0.22
Frontal Lobe5.62 ± 0.37
Globus Pallidus5.06 ± 0.47
Hypothalamus4.88 ± 0.27
Insula5.55 ± 0.45
Limbic Lobe5.71 ± 0.38
Mesencephalon5.48 ± 0.43
Myelencephalon5.63 ± 0.43
Occipital Lobe5.87 ± 0.43
Parietal Lobe5.66 ± 0.33
Pontine Tegmentum5.57 ± 0.38
Striatum5.25 ± 0.42
Subthalamus5.37 ± 0.37
Temporal Lobe5.59 ± 0.33
Thalamus5.77 ± 0.32
White Matter5.23 ± 0.28
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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