AutismKB 2.0

Annotation Detail for C1QB


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:C1QB ( - )
Gene Full Name: complement component 1, q subcomponent, B chain
Band: 1p36.12
Quick LinksEntrez ID:713; OMIM: 120570; Uniprot ID:C1QB_HUMAN; ENSEMBL ID: ENSG00000173369; HGNC ID: 1242
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus15 / 56401226
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult153 / 193912178
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor1 / 2638453
glioma10 / 10688393
head and neck tumor5 / 13630236
kidney tumor5 / 6895972
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal188 / 336030755
ovarian tumor4 / 7668252
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland7 / 33197210
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone5 / 7165569
bone marrow0 / 488010 
brain32 / 110098929
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye11 / 21105452
heart0 / 896260 
intestine16 / 23447268
kidney11 / 21177751
larynx0 / 241450 
liver5 / 20774324
lung30 / 33697489
lymph0 / 442700 
lymph node0 / 916100 
mammary gland5 / 15327132
mouth4 / 6705259
muscle1 / 1077159
nerve0 / 157680 
ovary6 / 10205158
pancreas18 / 21481283
parathyroid1 / 2053948
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta29 / 280825103
prostate4 / 18934521
salivary gland0 / 201550 
skin4 / 21057418
spleen18 / 53952333
stomach11 / 96619113
testis0 / 3304420 
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus9 / 23287838
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202953_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.95
Adipocyte15.45
AdrenalCortex34.05
Adrenalgland90.2
Amygdala37.1
Appendix18.05
AtrioventricularNode14.95
BDCA4+_DentriticCells21.55
Bonemarrow20.25
BronchialEpithelialCells15.3
CD105+_Endothelial370.35
CD14+_Monocytes17.3
CD19+_BCells(neg._sel.)10.85
CD33+_Myeloid19.2
CD34+16.75
CD4+_Tcells15.9
CD56+_NKCells14.9
CD71+_EarlyErythroid14.85
CD8+_Tcells12.7
CardiacMyocytes24.75
Caudatenucleus34.65
Cerebellum13.4
CerebellumPeduncles19.55
CiliaryGanglion14.3
CingulateCortex16.05
Colorectaladenocarcinoma15.95
DorsalRootGanglion27.1
FetalThyroid16.85
Fetalbrain16.05
Fetalliver28.7
Fetallung68.85
GlobusPallidus12.4
Heart1995
Hypothalamus59.5
Kidney13.95
Leukemia_chronicMyelogenousK-56214.2
Leukemia_promyelocytic-HL-607.7
Leukemialymphoblastic(MOLT-4)12
Liver219.9
Lung1813.2
Lymphnode247.85
Lymphoma_burkitts(Daudi)20.9
Lymphoma_burkitts(Raji)20.4
MedullaOblongata14.6
OccipitalLobe15.6
OlfactoryBulb112.5
Ovary165.25
Pancreas17.25
PancreaticIslet116
ParietalLobe18.25
Pituitary53.25
Placenta381.65
Pons16.3
PrefrontalCortex31.2
Prostate31.9
Salivarygland17.8
SkeletalMuscle20.05
Skin13.6
SmoothMuscle18.1
Spinalcord77.75
SubthalamicNucleus15.35
SuperiorCervicalGanglion25.95
TemporalLobe35.7
Testis13.85
TestisGermCell12.6
TestisIntersitial13.55
TestisLeydigCell19.9
TestisSeminiferousTubule13.95
Thalamus22.9
Thymus113.75
Thyroid21.9
Tongue24.9
Tonsil34.85
Trachea18.4
TrigeminalGanglion20.7
Uterus28.1
UterusCorpus20.95
WholeBlood14.15
Wholebrain41.35
colon17.05
pineal_day24.48
pineal_night22.72
retina181.925
small_intestine148.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P188263
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.46 ± 1.07
Basal Forebrain1.91 ± 0.3
Basal Part of Pons2.19 ± 0.64
Cerebellar Cortex1.83 ± 0.81
Cerebellar Nuclei2.24 ± 0.63
Claustrum2.86 ± 0.94
Epithalamus1.99 ± 0.92
Frontal Lobe1.85 ± 0.76
Globus Pallidus2.68 ± 0.51
Hypothalamus1.91 ± 0.62
Insula1.81 ± 0.37
Limbic Lobe1.98 ± 0.73
Mesencephalon2.07 ± 0.65
Myelencephalon2.05 ± 0.72
Occipital Lobe1.88 ± 0.79
Parietal Lobe1.96 ± 0.79
Pontine Tegmentum1.9 ± 0.77
Striatum2.15 ± 0.61
Subthalamus2 ± 0.74
Temporal Lobe1.96 ± 0.8
Thalamus1.99 ± 0.78
White Matter2.06 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
C1qbCBCerebellum0.97
1.45
C1qbCTXCerebral cortex0.7
0.56
C1qbHIPHippocampal region1.15
1.1
C1qbHPFHippocampal formation1.07
1.13
C1qbHYHypothalamus0.29
0.22
C1qbLSXLateral septal complex0.41
0.19
C1qbMBMidbrain0.62
0.93
C1qbMYMedulla0.58
0.54
C1qbOLFOlfactory bulb1.21
1.12
C1qbPPons0.31
0.41
C1qbPALPallidum0.26
0.17
C1qbRHPRetrohippocampal region0.91
1.05
C1qbsAMYStriatum-like amygdalar nuclei0.49
0.86
C1qbSTRStriatum0.35
0.35
C1qbSTRdStriatum dorsal region0.28
0.23
C1qbSTRvStriatum ventral region0.57
0.6
C1qbTHThalamus0.64
0.88
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00025116 15 142 156 FDHVITNMNNNYEPR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved