AutismKB 2.0

Annotation Detail for TNFRSF1A


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Basic Information Top
Gene Symbol:TNFRSF1A ( CD120a,FPF,MGC19588,TBP1,TNF-R,TNF-R-I,TNF-R55,TNFAR,TNFR1,TNFR55,TNFR60,p55,p55-R,p60 )
Gene Full Name: tumor necrosis factor receptor superfamily, member 1A
Band: 12p13.31
Quick LinksEntrez ID:7132; OMIM: 191190; Uniprot ID:TNR1A_HUMAN; ENSEMBL ID: ENSG00000067182; HGNC ID: 11916
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst5 / 6231980
fetus49 / 56401286
neonate33 / 310971061
infant1 / 2362042
juvenile40 / 55556719
adult495 / 1939121255
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor31 / 94178329
cervical tumor10 / 34366290
chondrosarcoma11 / 82823132
colorectal tumor8 / 11424670
esophageal tumor11 / 17290636
gastrointestinal tumor25 / 119369209
germ cell tumor179 / 263845678
glioma110 / 1068831029
head and neck tumor10 / 13630273
kidney tumor6 / 6895987
leukemia15 / 95842156
liver tumor32 / 96359332
lung tumor14 / 103127135
lymphoma7 / 7175597
non-neoplasia72 / 97250740
normal883 / 3360307262
ovarian tumor9 / 76682117
pancreatic tumor12 / 104616114
primitive neuroectodermal tumor of the CNS42 / 125680334
prostate cancer12 / 102680116
retinoblastoma0 / 463560 
skin tumor10 / 12494980
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor15 / 90257166
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland26 / 33197783
ascites8 / 40015199
bladder12 / 29757403
blood69 / 123478558
bone11 / 71655153
bone marrow8 / 48801163
brain301 / 1100989273
cervix13 / 48171269
connective tissue99 / 149255663
ear0 / 162120 
embryonic tissue21 / 21572297
esophagus14 / 20209692
eye12 / 21105456
heart14 / 89626156
intestine95 / 234472405
kidney66 / 211777311
larynx2 / 2414582
liver36 / 207743173
lung88 / 336974261
lymph0 / 442700 
lymph node0 / 916100 
mammary gland37 / 153271241
mouth23 / 67052343
muscle8 / 10771574
nerve8 / 15768507
ovary10 / 10205197
pancreas12 / 21481255
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta75 / 280825267
prostate51 / 189345269
salivary gland0 / 201550 
skin53 / 210574251
spleen61 / 539521130
stomach30 / 96619310
testis70 / 330442211
thymus59 / 81131727
thyroid6 / 47473126
tonsil0 / 169990 
trachea28 / 52413534
umbilical cord2 / 13680146
uterus98 / 232878420
vascular37 / 51780714
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207643_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts51.1
Adipocyte297.35
AdrenalCortex262.7
Adrenalgland181.4
Amygdala38.85
Appendix67.55
AtrioventricularNode57.9
BDCA4+_DentriticCells180.85
Bonemarrow92.1
BronchialEpithelialCells90.3
CD105+_Endothelial66.75
CD14+_Monocytes693.3
CD19+_BCells(neg._sel.)24.7
CD33+_Myeloid480.15
CD34+242.3
CD4+_Tcells108.05
CD56+_NKCells248.5
CD71+_EarlyErythroid30.75
CD8+_Tcells114.65
CardiacMyocytes184.7
Caudatenucleus32.5
Cerebellum16.95
CerebellumPeduncles61.15
CiliaryGanglion82.3
CingulateCortex53.9
Colorectaladenocarcinoma72.85
DorsalRootGanglion48.3
FetalThyroid173.5
Fetalbrain37.15
Fetalliver47.4
Fetallung247.65
GlobusPallidus37.3
Heart224.15
Hypothalamus44.65
Kidney77.05
Leukemia_chronicMyelogenousK-56251.8
Leukemia_promyelocytic-HL-6016.65
Leukemialymphoblastic(MOLT-4)53.6
Liver132.3
Lung834
Lymphnode109.55
Lymphoma_burkitts(Daudi)43.6
Lymphoma_burkitts(Raji)13.55
MedullaOblongata18.65
OccipitalLobe29.1
OlfactoryBulb118
Ovary106.95
Pancreas69
PancreaticIslet157.65
ParietalLobe30.1
Pituitary68.3
Placenta294.85
Pons36.05
PrefrontalCortex45.4
Prostate305.85
Salivarygland46.1
SkeletalMuscle93.15
Skin121.8
SmoothMuscle296.95
Spinalcord93.9
SubthalamicNucleus37.35
SuperiorCervicalGanglion33.25
TemporalLobe35.1
Testis50.25
TestisGermCell71.75
TestisIntersitial24.05
TestisLeydigCell41.3
TestisSeminiferousTubule46.9
Thalamus55.35
Thymus81.5
Thyroid315.2
Tongue128.85
Tonsil66.35
Trachea68.5
TrigeminalGanglion57.5
Uterus216.25
UterusCorpus112.7
WholeBlood962.65
Wholebrain22.3
colon97.05
pineal_day74.3
pineal_night72.28
retina167.2
small_intestine117.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15752_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.95 ± 0.59
Basal Forebrain3.32 ± 0.57
Basal Part of Pons2.95 ± 0.55
Cerebellar Cortex3.11 ± 0.57
Cerebellar Nuclei3.8 ± 0.57
Claustrum3.75 ± 0.76
Epithalamus4.53 ± 0.45
Frontal Lobe3.51 ± 0.66
Globus Pallidus4.93 ± 0.27
Hypothalamus3.61 ± 0.88
Insula3.56 ± 1.01
Limbic Lobe3.4 ± 0.67
Mesencephalon3.74 ± 0.58
Myelencephalon3.66 ± 0.68
Occipital Lobe3.66 ± 0.77
Parietal Lobe3.58 ± 0.67
Pontine Tegmentum3.68 ± 0.71
Striatum3.66 ± 0.76
Subthalamus3.48 ± 1.51
Temporal Lobe3.67 ± 0.74
Thalamus3.73 ± 0.58
White Matter3.66 ± 0.26
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tnfrsf1aCBCerebellum64.36
43.01
Tnfrsf1aCTXCerebral cortex39.63
23.17
Tnfrsf1aHIPHippocampal region31.79
18.26
Tnfrsf1aHPFHippocampal formation39.48
25.91
Tnfrsf1aHYHypothalamus39.4
22.84
Tnfrsf1aLSXLateral septal complex27.6
13.97
Tnfrsf1aMBMidbrain34.21
23.01
Tnfrsf1aMYMedulla64.68
49.8
Tnfrsf1aOLFOlfactory bulb68.06
37.27
Tnfrsf1aPPons57.5
42.51
Tnfrsf1aPALPallidum30.56
18.36
Tnfrsf1aRHPRetrohippocampal region51.2
34.64
Tnfrsf1asAMYStriatum-like amygdalar nuclei22.3
11.56
Tnfrsf1aSTRStriatum22.28
11.23
Tnfrsf1aSTRdStriatum dorsal region14.76
7.71
Tnfrsf1aSTRvStriatum ventral region44.51
20.19
Tnfrsf1aTHThalamus29.61
18.29
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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