AutismKB 2.0

Annotation Detail for TNXB


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Basic Information Top
Gene Symbol:TNXB ( HXBL,TENX,TN-X,TNX,TNXB1,TNXB2,TNXBS,XB,XBS )
Gene Full Name: tenascin XB
Band: 6p21.33-p21.32
Quick LinksEntrez ID:7148; OMIM: 600985; Uniprot ID:TENX_HUMAN; ENSEMBL ID: ENSG00000168477; HGNC ID: 11976
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst0 / 623190 
fetus14 / 56401224
neonate1 / 3109732
infant0 / 236200 
juvenile2 / 5555635
adult108 / 193912155
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus7 / 56401212
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult37 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor7 / 9417874
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor4 / 11424635
esophageal tumor3 / 17290173
gastrointestinal tumor2 / 11936916
germ cell tumor3 / 26384511
glioma3 / 10688328
head and neck tumor12 / 13630288
kidney tumor2 / 6895929
leukemia7 / 9584273
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal111 / 336030733
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal52 / 336030715
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood10 / 12347880
bone2 / 7165527
bone marrow0 / 488010 
brain13 / 110098911
cervix2 / 4817141
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus3 / 20209148
eye7 / 21105433
heart1 / 8962611
intestine9 / 23447238
kidney8 / 21177737
larynx5 / 24145207
liver2 / 2077439
lung11 / 33697432
lymph1 / 4427022
lymph node4 / 9161043
mammary gland8 / 15327152
mouth5 / 6705274
muscle2 / 10771518
nerve1 / 1576863
ovary3 / 10205129
pancreas3 / 21481213
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta16 / 28082556
prostate11 / 18934558
salivary gland0 / 201550 
skin11 / 21057452
spleen1 / 5395218
stomach1 / 9661910
testis4 / 33044212
thymus0 / 811310 
thyroid16 / 47473337
tonsil2 / 16999117
trachea0 / 524130 
umbilical cord1 / 1368073
uterus3 / 23287812
vascular0 / 517800 
adipose tissue4 / 13106305
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone0 / 716550 
bone marrow0 / 488010 
brain6 / 11009895
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye1 / 2110544
heart1 / 8962611
intestine8 / 23447234
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung11 / 33697432
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle4 / 10771537
nerve1 / 1576863
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate2 / 18934510
salivary gland0 / 201550 
skin2 / 2105749
spleen1 / 5395218
stomach1 / 9661910
testis5 / 33044215
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 216333_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts24.4
Adipocyte66.75
AdrenalCortex4439.55
Adrenalgland1305.55
Amygdala20.95
Appendix137.45
AtrioventricularNode83.65
BDCA4+_DentriticCells15.25
Bonemarrow33.05
BronchialEpithelialCells12.35
CD105+_Endothelial77.2
CD14+_Monocytes8.55
CD19+_BCells(neg._sel.)18.85
CD33+_Myeloid17.2
CD34+18.85
CD4+_Tcells30.05
CD56+_NKCells13.45
CD71+_EarlyErythroid95.45
CD8+_Tcells25.15
CardiacMyocytes30.15
Caudatenucleus27.4
Cerebellum37.75
CerebellumPeduncles54.4
CiliaryGanglion119
CingulateCortex37.85
Colorectaladenocarcinoma12.15
DorsalRootGanglion61.7
FetalThyroid156.5
Fetalbrain27.9
Fetalliver22.35
Fetallung48.9
GlobusPallidus23.3
Heart399.05
Hypothalamus33.8
Kidney34.6
Leukemia_chronicMyelogenousK-56230.2
Leukemia_promyelocytic-HL-6014.95
Leukemialymphoblastic(MOLT-4)23.2
Liver42.35
Lung212.55
Lymphnode53.4
Lymphoma_burkitts(Daudi)34.05
Lymphoma_burkitts(Raji)15.35
MedullaOblongata29.1
OccipitalLobe22.7
OlfactoryBulb69.9
Ovary50.9
Pancreas23.3
PancreaticIslet34.75
ParietalLobe31.85
Pituitary43.85
Placenta58.35
Pons30.1
PrefrontalCortex34.15
Prostate42.7
Salivarygland20.7
SkeletalMuscle67.15
Skin64.15
SmoothMuscle23
Spinalcord52.1
SubthalamicNucleus25.6
SuperiorCervicalGanglion85.25
TemporalLobe28.95
Testis29.85
TestisGermCell107.45
TestisIntersitial64.35
TestisLeydigCell51.45
TestisSeminiferousTubule45.7
Thalamus34.35
Thymus53.65
Thyroid111
Tongue105.05
Tonsil42
Trachea92.65
TrigeminalGanglion44.1
Uterus205.45
UterusCorpus67.45
WholeBlood21.2
Wholebrain17.75
colon29.65
pineal_day39.84
pineal_night32
retina34.975
small_intestine63.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P213884
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.35 ± 0.82
Basal Forebrain8.04 ± 0.5
Basal Part of Pons8.36 ± 0.54
Cerebellar Cortex7.67 ± 0.5
Cerebellar Nuclei8.36 ± 0.35
Claustrum8.43 ± 0.52
Epithalamus7.4 ± 0.77
Frontal Lobe8.2 ± 0.67
Globus Pallidus8.62 ± 0.57
Hypothalamus8.16 ± 0.51
Insula8.07 ± 0.73
Limbic Lobe8.27 ± 0.68
Mesencephalon8.26 ± 0.62
Myelencephalon8.2 ± 0.65
Occipital Lobe8.21 ± 0.68
Parietal Lobe8.11 ± 0.65
Pontine Tegmentum8.1 ± 0.57
Striatum8.54 ± 0.74
Subthalamus7.65 ± 0.65
Temporal Lobe8.09 ± 0.77
Thalamus8.25 ± 0.55
White Matter8.1 ± 0.72
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
TnxbCBCerebellum14.83
20.37
TnxbCTXCerebral cortex13.02
9.59
TnxbHIPHippocampal region23.45
26.98
TnxbHPFHippocampal formation20.72
20.97
TnxbHYHypothalamus5.3
4.27
TnxbLSXLateral septal complex7.95
5.68
TnxbMBMidbrain5.39
5.77
TnxbMYMedulla12.48
15.02
TnxbOLFOlfactory bulb25.78
22.45
TnxbPPons9.21
10.13
TnxbPALPallidum4.81
3.74
TnxbRHPRetrohippocampal region17.53
14.27
TnxbsAMYStriatum-like amygdalar nuclei4.12
2.87
TnxbSTRStriatum5.46
3.84
TnxbSTRdStriatum dorsal region3.96
2.79
TnxbSTRvStriatum ventral region10.02
6.75
TnxbTHThalamus6.53
5.48
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00092441 10 3622 3631 FLLYGLHEGK Peptide Atlas
TENX_HUMAN_4281 9 4281 4289 NFRSPAGGG PRIDE
TENX_HUMAN_889 8 889 896 PSLSQPPR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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