AutismKB 2.0

Annotation Detail for TPD52L1


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Basic Information Top
Gene Symbol:TPD52L1 ( D53,MGC8556,TPD52L2,hD53 )
Gene Full Name: tumor protein D52-like 1
Band: 6q22-q23
Quick LinksEntrez ID:7164; OMIM: 604069; Uniprot ID:TPD53_HUMAN; ENSEMBL ID: ENSG00000111907; HGNC ID: 12006
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst0 / 623190 
fetus17 / 56401230
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult97 / 193912150
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor11 / 94178116
cervical tumor2 / 3436658
chondrosarcoma7 / 8282384
colorectal tumor7 / 11424661
esophageal tumor1 / 1729057
gastrointestinal tumor3 / 11936925
germ cell tumor7 / 26384526
glioma9 / 10688384
head and neck tumor2 / 13630214
kidney tumor6 / 6895987
leukemia1 / 9584210
liver tumor2 / 9635920
lung tumor19 / 103127184
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal115 / 336030734
ovarian tumor4 / 7668252
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer12 / 102680116
retinoblastoma0 / 463560 
skin tumor11 / 12494988
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor13 / 90257144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder2 / 2975767
blood0 / 1234780 
bone7 / 7165597
bone marrow1 / 4880120
brain39 / 110098935
cervix2 / 4817141
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus1 / 2020949
eye11 / 21105452
heart6 / 8962666
intestine12 / 23447251
kidney15 / 21177770
larynx0 / 241450 
liver6 / 20774328
lung29 / 33697486
lymph0 / 442700 
lymph node0 / 916100 
mammary gland19 / 153271123
mouth0 / 670520 
muscle9 / 10771583
nerve0 / 157680 
ovary4 / 10205139
pancreas0 / 2148120 
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta12 / 28082542
prostate20 / 189345105
salivary gland2 / 2015599
skin16 / 21057475
spleen0 / 539520 
stomach2 / 9661920
testis2 / 3304426
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus16 / 23287868
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203786_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts368
Adipocyte26.35
AdrenalCortex347.75
Adrenalgland623.2
Amygdala253.7
Appendix30.4
AtrioventricularNode22.5
BDCA4+_DentriticCells4.55
Bonemarrow21.75
BronchialEpithelialCells336.8
CD105+_Endothelial5.8
CD14+_Monocytes14.6
CD19+_BCells(neg._sel.)5.1
CD33+_Myeloid8.75
CD34+12.1
CD4+_Tcells8.05
CD56+_NKCells6.4
CD71+_EarlyErythroid6.7
CD8+_Tcells7.45
CardiacMyocytes30.75
Caudatenucleus529.2
Cerebellum13.85
CerebellumPeduncles20.45
CiliaryGanglion19.9
CingulateCortex54.7
Colorectaladenocarcinoma127.9
DorsalRootGanglion20.6
FetalThyroid30.9
Fetalbrain25.85
Fetalliver24.65
Fetallung18.8
GlobusPallidus49.6
Heart66.6
Hypothalamus88.05
Kidney34.45
Leukemia_chronicMyelogenousK-562238.4
Leukemia_promyelocytic-HL-6015.8
Leukemialymphoblastic(MOLT-4)14.15
Liver271.6
Lung35.7
Lymphnode22.2
Lymphoma_burkitts(Daudi)9.4
Lymphoma_burkitts(Raji)23.85
MedullaOblongata173.35
OccipitalLobe46.55
OlfactoryBulb28
Ovary17.85
Pancreas25.7
PancreaticIslet65.1
ParietalLobe35.25
Pituitary114.85
Placenta30.25
Pons75.8
PrefrontalCortex296.9
Prostate275.85
Salivarygland612.1
SkeletalMuscle47.65
Skin25.8
SmoothMuscle29.5
Spinalcord48.05
SubthalamicNucleus35.75
SuperiorCervicalGanglion32.45
TemporalLobe74.05
Testis17.1
TestisGermCell23.9
TestisIntersitial22.5
TestisLeydigCell26.6
TestisSeminiferousTubule18.8
Thalamus40.05
Thymus17.7
Thyroid160.3
Tongue185.15
Tonsil25.8
Trachea197.55
TrigeminalGanglion25.65
Uterus91.4
UterusCorpus23.25
WholeBlood10.8
Wholebrain113.9
colon27.35
pineal_day1223.36
pineal_night1672.1
retina152.25
small_intestine26.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P31143
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.71 ± 0.55
Basal Forebrain9.25 ± 0.8
Basal Part of Pons8.1 ± 0.34
Cerebellar Cortex7.46 ± 0.55
Cerebellar Nuclei8.04 ± 0.84
Claustrum7.76 ± 1.37
Epithalamus9.08 ± 0.53
Frontal Lobe8.59 ± 0.65
Globus Pallidus9.7 ± 0.38
Hypothalamus9.78 ± 0.67
Insula8.33 ± 0.45
Limbic Lobe8.6 ± 0.7
Mesencephalon8.3 ± 1.21
Myelencephalon8.44 ± 1.08
Occipital Lobe8.74 ± 0.47
Parietal Lobe8.94 ± 0.71
Pontine Tegmentum9.2 ± 1.07
Striatum11.02 ± 0.83
Subthalamus8.82 ± 0.38
Temporal Lobe8.49 ± 0.5
Thalamus7.55 ± 0.82
White Matter6.75 ± 0.61
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tpd52l1CBCerebellum0.78
1.22
Tpd52l1CTXCerebral cortex1.09
0.97
Tpd52l1HIPHippocampal region3.78
3.74
Tpd52l1HPFHippocampal formation2.85
2.71
Tpd52l1HYHypothalamus0.79
0.79
Tpd52l1LSXLateral septal complex6.08
5.61
Tpd52l1MBMidbrain2.47
3.67
Tpd52l1MYMedulla1.15
1.87
Tpd52l1OLFOlfactory bulb2.74
2.67
Tpd52l1PPons0.91
2.12
Tpd52l1PALPallidum0.53
0.53
Tpd52l1RHPRetrohippocampal region1.49
1.44
Tpd52l1sAMYStriatum-like amygdalar nuclei0.82
0.86
Tpd52l1STRStriatum0.97
0.91
Tpd52l1STRdStriatum dorsal region0.5
0.5
Tpd52l1STRvStriatum ventral region0.42
0.34
Tpd52l1THThalamus11.26
11.76
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00078427 12 86 97 SWHDMQTTTAYK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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