AutismKB 2.0

Annotation Detail for TPSAB1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TPSAB1 ( MGC104064,TPS1,TPS2,TPSB1 )
Gene Full Name: tryptase alpha/beta 1
Band: 16p13.3
Quick LinksEntrez ID:7177; OMIM: 191080; Uniprot ID:TRYB1_HUMAN; ENSEMBL ID: ENSG00000172236; HGNC ID: 12019
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult43 / 193912122
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor3 / 11424626
esophageal tumor1 / 1729057
gastrointestinal tumor7 / 11936958
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal42 / 336030712
ovarian tumor0 / 766820 
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow1 / 4880120
brain0 / 11009890 
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus1 / 2020949
eye9 / 21105442
heart0 / 896260 
intestine13 / 23447255
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung8 / 33697423
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth2 / 6705229
muscle0 / 1077150 
nerve2 / 15768126
ovary0 / 1020510 
pancreas12 / 21481255
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate2 / 18934510
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach8 / 9661982
testis2 / 3304426
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217023_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.2
Adipocyte5.75
AdrenalCortex6.15
Adrenalgland4.9
Amygdala5.9
Appendix6.05
AtrioventricularNode4.65
BDCA4+_DentriticCells5.9
Bonemarrow5.75
BronchialEpithelialCells5.4
CD105+_Endothelial5.9
CD14+_Monocytes5.85
CD19+_BCells(neg._sel.)5.3
CD33+_Myeloid7.45
CD34+7.4
CD4+_Tcells6.3
CD56+_NKCells6.5
CD71+_EarlyErythroid5.4
CD8+_Tcells5.6
CardiacMyocytes14.3
Caudatenucleus5.2
Cerebellum4.7
CerebellumPeduncles6.6
CiliaryGanglion4.25
CingulateCortex5.9
Colorectaladenocarcinoma5.5
DorsalRootGanglion4.7
FetalThyroid5.55
Fetalbrain5.75
Fetalliver5
Fetallung4.45
GlobusPallidus4.35
Heart7.55
Hypothalamus6.15
Kidney4.85
Leukemia_chronicMyelogenousK-5625.15
Leukemia_promyelocytic-HL-605.1
Leukemialymphoblastic(MOLT-4)4.55
Liver7.5
Lung297.1
Lymphnode7.3
Lymphoma_burkitts(Daudi)7.35
Lymphoma_burkitts(Raji)8.2
MedullaOblongata5.3
OccipitalLobe5.1
OlfactoryBulb4.6
Ovary3.85
Pancreas4.65
PancreaticIslet6.2
ParietalLobe6.1
Pituitary6.8
Placenta5.8
Pons5.55
PrefrontalCortex7.05
Prostate13.8
Salivarygland5.45
SkeletalMuscle8.4
Skin7.85
SmoothMuscle6.55
Spinalcord6.2
SubthalamicNucleus5.25
SuperiorCervicalGanglion7.8
TemporalLobe5.25
Testis5.1
TestisGermCell5
TestisIntersitial5.5
TestisLeydigCell5.85
TestisSeminiferousTubule5.65
Thalamus5.9
Thymus8
Thyroid7.4
Tongue5.85
Tonsil7.9
Trachea14.7
TrigeminalGanglion5.8
Uterus13.3
UterusCorpus18.4
WholeBlood5.85
Wholebrain4.6
colon7.15
pineal_day7.62
pineal_night13.02
retina15.425
small_intestine9.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13676_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.61 ± 1.06
Basal Forebrain2.02 ± 0.22
Basal Part of Pons1.76 ± 0.36
Cerebellar Cortex2.05 ± 0.77
Cerebellar Nuclei2.69 ± 0.88
Claustrum3.07 ± 0.86
Epithalamus1.83 ± 0.84
Frontal Lobe2.03 ± 0.73
Globus Pallidus2.93 ± 0.81
Hypothalamus2.19 ± 0.8
Insula2.06 ± 0.34
Limbic Lobe2.18 ± 0.73
Mesencephalon2.35 ± 0.75
Myelencephalon2.18 ± 0.67
Occipital Lobe2.17 ± 0.7
Parietal Lobe2.15 ± 0.71
Pontine Tegmentum2.28 ± 0.78
Striatum2.24 ± 0.55
Subthalamus2.29 ± 0.72
Temporal Lobe2.11 ± 0.74
Thalamus2.08 ± 0.62
White Matter2.71 ± 0.64
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00437989 10 222 231 GDSGGPLVCK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved