AutismKB 2.0

Annotation Detail for TPTE


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Basic Information Top
Gene Symbol:TPTE ( CT44,PTEN2 )
Gene Full Name: transmembrane phosphatase with tensin homology
Band: 21p11.2
Quick LinksEntrez ID:7179; OMIM: 604336; Uniprot ID:TPTE_HUMAN; ENSEMBL ID: ENSG00000166157; HGNC ID: 12023
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus16 / 56401228
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult8 / 19391214
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal51 / 336030715
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis51 / 330442154
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220205_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.75
Adipocyte4.8
AdrenalCortex5.5
Adrenalgland4.25
Amygdala5.05
Appendix6.75
AtrioventricularNode4.1
BDCA4+_DentriticCells5.2
Bonemarrow4.95
BronchialEpithelialCells4.8
CD105+_Endothelial4.9
CD14+_Monocytes5.15
CD19+_BCells(neg._sel.)5.2
CD33+_Myeloid6.25
CD34+5.95
CD4+_Tcells5.2
CD56+_NKCells5.6
CD71+_EarlyErythroid4.6
CD8+_Tcells4.6
CardiacMyocytes6.7
Caudatenucleus4.4
Cerebellum3.95
CerebellumPeduncles5.7
CiliaryGanglion3.7
CingulateCortex5.05
Colorectaladenocarcinoma4.85
DorsalRootGanglion4.5
FetalThyroid4.8
Fetalbrain4.75
Fetalliver4.3
Fetallung3.85
GlobusPallidus3.7
Heart6.8
Hypothalamus5.3
Kidney4.15
Leukemia_chronicMyelogenousK-56212.55
Leukemia_promyelocytic-HL-604.35
Leukemialymphoblastic(MOLT-4)3.85
Liver6.65
Lung5.3
Lymphnode4.1
Lymphoma_burkitts(Daudi)6.35
Lymphoma_burkitts(Raji)7.05
MedullaOblongata4.45
OccipitalLobe4.35
OlfactoryBulb3.85
Ovary3.4
Pancreas4.05
PancreaticIslet5.2
ParietalLobe5.3
Pituitary5.7
Placenta4.95
Pons4.7
PrefrontalCortex5.95
Prostate5.65
Salivarygland3.95
SkeletalMuscle6.15
Skin4
SmoothMuscle5.55
Spinalcord5.25
SubthalamicNucleus4.55
SuperiorCervicalGanglion6.05
TemporalLobe4.5
Testis759.35
TestisGermCell224.1
TestisIntersitial485.9
TestisLeydigCell538.6
TestisSeminiferousTubule362.75
Thalamus5
Thymus3.75
Thyroid5.95
Tongue5
Tonsil4.8
Trachea4.05
TrigeminalGanglion5.2
Uterus3.95
UterusCorpus4.55
WholeBlood5.3
Wholebrain4.1
colon4.9
pineal_day5.98
pineal_night5.9
retina5.875
small_intestine4.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P64966
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.78 ± 1.1
Basal Forebrain2.23 ± 0.19
Basal Part of Pons1.92 ± 0.34
Cerebellar Cortex2.1 ± 0.64
Cerebellar Nuclei2.61 ± 0.78
Claustrum3.18 ± 0.84
Epithalamus2.24 ± 0.65
Frontal Lobe2.17 ± 0.64
Globus Pallidus2.86 ± 0.26
Hypothalamus2.32 ± 0.65
Insula2.16 ± 0.52
Limbic Lobe2.31 ± 0.68
Mesencephalon2.52 ± 0.69
Myelencephalon2.33 ± 0.65
Occipital Lobe2.35 ± 0.56
Parietal Lobe2.29 ± 0.64
Pontine Tegmentum2.4 ± 0.75
Striatum2.56 ± 0.57
Subthalamus2.49 ± 0.67
Temporal Lobe2.17 ± 0.58
Thalamus2.32 ± 0.58
White Matter4.79 ± 1.06
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018