AutismKB 2.0

Annotation Detail for TRAF1


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Basic Information Top
Gene Symbol:TRAF1 ( EBI6,MGC:10353 )
Gene Full Name: TNF receptor-associated factor 1
Band: 9q33.2
Quick LinksEntrez ID:7185; OMIM: 601711; Uniprot ID:TRAF1_HUMAN; ENSEMBL ID: ENSG00000056558; HGNC ID: 12031
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus10 / 56401217
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult51 / 193912126
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor5 / 26384518
glioma2 / 10688318
head and neck tumor4 / 13630229
kidney tumor1 / 6895914
leukemia6 / 9584262
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma3 / 7175541
non-neoplasia3 / 9725030
normal68 / 336030720
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor7 / 12494956
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood8 / 12347864
bone0 / 716550 
bone marrow0 / 488010 
brain15 / 110098913
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine5 / 23447221
kidney10 / 21177747
larynx3 / 24145124
liver0 / 2077430 
lung23 / 33697468
lymph1 / 4427022
lymph node3 / 9161032
mammary gland9 / 15327158
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin7 / 21057433
spleen0 / 539520 
stomach1 / 9661910
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord2 / 13680146
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205599_at
Cell line Expression level Expression bar
721_B_lymphoblasts131.8
Adipocyte3.15
AdrenalCortex3.25
Adrenalgland2.7
Amygdala3.4
Appendix3.2
AtrioventricularNode2.4
BDCA4+_DentriticCells4.75
Bonemarrow3.15
BronchialEpithelialCells3.2
CD105+_Endothelial3.25
CD14+_Monocytes3.5
CD19+_BCells(neg._sel.)4
CD33+_Myeloid4.2
CD34+4.15
CD4+_Tcells39.5
CD56+_NKCells8.7
CD71+_EarlyErythroid3
CD8+_Tcells38.6
CardiacMyocytes3.95
Caudatenucleus2.85
Cerebellum2.6
CerebellumPeduncles3.6
CiliaryGanglion2.25
CingulateCortex3.25
Colorectaladenocarcinoma3.25
DorsalRootGanglion2.45
FetalThyroid3.15
Fetalbrain3.25
Fetalliver2.75
Fetallung2.7
GlobusPallidus2.35
Heart4.05
Hypothalamus3.55
Kidney2.55
Leukemia_chronicMyelogenousK-5622.95
Leukemia_promyelocytic-HL-6014.35
Leukemialymphoblastic(MOLT-4)2.6
Liver4.3
Lung3.6
Lymphnode7.4
Lymphoma_burkitts(Daudi)4.1
Lymphoma_burkitts(Raji)40.8
MedullaOblongata2.95
OccipitalLobe2.9
OlfactoryBulb2.5
Ovary2.1
Pancreas2.55
PancreaticIslet3.45
ParietalLobe3.3
Pituitary3.8
Placenta3.35
Pons3.05
PrefrontalCortex4.1
Prostate3.8
Salivarygland2.5
SkeletalMuscle3.65
Skin2.4
SmoothMuscle3.7
Spinalcord3.4
SubthalamicNucleus2.9
SuperiorCervicalGanglion6.4
TemporalLobe2.9
Testis2.8
TestisGermCell2.75
TestisIntersitial2.7
TestisLeydigCell3.15
TestisSeminiferousTubule2.75
Thalamus3.25
Thymus2.6
Thyroid4.1
Tongue3.1
Tonsil3.35
Trachea2.7
TrigeminalGanglion3.1
Uterus2.65
UterusCorpus2.85
WholeBlood3.75
Wholebrain2.8
colon3.25
pineal_day14.36
pineal_night26.8
retina3.95
small_intestine3.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P89891
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.71 ± 0.71
Basal Forebrain4.14 ± 0.64
Basal Part of Pons4.3 ± 0.38
Cerebellar Cortex3.73 ± 0.41
Cerebellar Nuclei4.13 ± 0.57
Claustrum3.62 ± 0.82
Epithalamus4.47 ± 0.44
Frontal Lobe3.88 ± 0.64
Globus Pallidus5.46 ± 0.37
Hypothalamus3.93 ± 0.58
Insula3.7 ± 0.35
Limbic Lobe3.65 ± 0.67
Mesencephalon4.12 ± 0.66
Myelencephalon3.95 ± 0.66
Occipital Lobe4.17 ± 0.6
Parietal Lobe3.94 ± 0.68
Pontine Tegmentum4.05 ± 0.56
Striatum4.25 ± 0.49
Subthalamus4.1 ± 0.38
Temporal Lobe3.74 ± 0.55
Thalamus4.14 ± 0.56
White Matter6.17 ± 0.3
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Traf1CBCerebellum16.17
17.81
Traf1CTXCerebral cortex43.3
30.66
Traf1HIPHippocampal region31.1
32.99
Traf1HPFHippocampal formation39.02
37.1
Traf1HYHypothalamus11.84
8.39
Traf1LSXLateral septal complex53.82
38.01
Traf1MBMidbrain15.21
12.85
Traf1MYMedulla21.23
22.89
Traf1OLFOlfactory bulb51.81
42.63
Traf1PPons17.31
17.53
Traf1PALPallidum11.43
9.34
Traf1RHPRetrohippocampal region54.07
44.52
Traf1sAMYStriatum-like amygdalar nuclei26.4
17.37
Traf1STRStriatum28.64
19.76
Traf1STRdStriatum dorsal region27.55
19.32
Traf1STRvStriatum ventral region24.55
15.94
Traf1THThalamus21.1
15.94
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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