Annotation Detail for TRAF2
Basic Information Top
| Gene Symbol: | TRAF2 ( MGC:45012,TRAP,TRAP3 ) |
|---|---|
| Gene Full Name: | TNF receptor-associated factor 2 |
| Band: | 9q34.3 |
| Quick Links | Entrez ID:7186; OMIM: 601895; Uniprot ID:TRAF2_HUMAN; ENSEMBL ID: ENSG00000127191; HGNC ID: 12032 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.522506
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 4 / 70761 | 56 |  |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 22 / 564012 | 39 |  |
| neonate | 7 / 31097 | 225 |  |
| infant | 0 / 23620 | 0 | |
| juvenile | 16 / 55556 | 287 | |
| adult | 118 / 1939121 | 60 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 13 / 94178 | 138 | |
| cervical tumor | 2 / 34366 | 58 | |
| chondrosarcoma | 4 / 82823 | 48 | |
| colorectal tumor | 5 / 114246 | 43 | |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 6 / 119369 | 50 | |
| germ cell tumor | 39 / 263845 | 147 | |
| glioma | 15 / 106883 | 140 | |
| head and neck tumor | 6 / 136302 | 44 | |
| kidney tumor | 3 / 68959 | 43 | |
| leukemia | 5 / 95842 | 52 | |
| liver tumor | 9 / 96359 | 93 | |
| lung tumor | 8 / 103127 | 77 | |
| lymphoma | 9 / 71755 | 125 | |
| non-neoplasia | 10 / 97250 | 102 | |
| normal | 202 / 3360307 | 60 | |
| ovarian tumor | 5 / 76682 | 65 | |
| pancreatic tumor | 6 / 104616 | 57 | |
| primitive neuroectodermal tumor of the CNS | 28 / 125680 | 222 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 3 / 46356 | 64 | |
| skin tumor | 3 / 124949 | 24 | |
| soft tissue/muscle tissue tumor | 5 / 125191 | 39 | |
| uterine tumor | 2 / 90257 | 22 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 2 / 33197 | 60 | |
| ascites | 5 / 40015 | 124 | |
| bladder | 2 / 29757 | 67 | |
| blood | 8 / 123478 | 64 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 5 / 48801 | 102 | |
| brain | 88 / 1100989 | 79 | |
| cervix | 9 / 48171 | 186 | |
| connective tissue | 18 / 149255 | 120 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 6 / 215722 | 27 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 11 / 211054 | 52 | |
| heart | 2 / 89626 | 22 | |
| intestine | 18 / 234472 | 76 | |
| kidney | 21 / 211777 | 99 | |
| larynx | 0 / 24145 | 0 | |
| liver | 9 / 207743 | 43 | |
| lung | 19 / 336974 | 56 | |
| lymph | 5 / 44270 | 112 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 14 / 153271 | 91 | |
| mouth | 7 / 67052 | 104 | |
| muscle | 1 / 107715 | 9 |  |
| nerve | 0 / 15768 | 0 | |
| ovary | 9 / 102051 | 88 | |
| pancreas | 6 / 214812 | 27 | |
| parathyroid | 1 / 20539 | 48 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 12 / 280825 | 42 | |
| prostate | 8 / 189345 | 42 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 17 / 210574 | 80 | |
| spleen | 24 / 53952 | 444 | |
| stomach | 3 / 96619 | 31 | |
| testis | 31 / 330442 | 93 | |
| thymus | 34 / 81131 | 419 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 5 / 52413 | 95 | |
| umbilical cord | 2 / 13680 | 146 | |
| uterus | 7 / 232878 | 30 | |
| vascular | 3 / 51780 | 57 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 204413_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 8.65 | |
| Adipocyte | 5.1 | |
| AdrenalCortex | 5.85 | |
| Adrenalgland | 4.3 | |
| Amygdala | 4.9 | |
| Appendix | 5.05 | |
| AtrioventricularNode | 4.15 | |
| BDCA4+_DentriticCells | 5.45 | |
| Bonemarrow | 5.1 | |
| BronchialEpithelialCells | 5 | |
| CD105+_Endothelial | 6.1 | |
| CD14+_Monocytes | 5.35 | |
| CD19+_BCells(neg._sel.) | 5.8 | |
| CD33+_Myeloid | 6.5 | |
| CD34+ | 6.85 | |
| CD4+_Tcells | 8.35 | |
| CD56+_NKCells | 6.25 | |
| CD71+_EarlyErythroid | 5.55 | |
| CD8+_Tcells | 6.05 | |
| CardiacMyocytes | 6.45 | |
| Caudatenucleus | 5.35 | |
| Cerebellum | 4.15 | |
| CerebellumPeduncles | 12.4 | |
| CiliaryGanglion | 6.85 | |
| CingulateCortex | 6.25 | |
| Colorectaladenocarcinoma | 5.25 | |
| DorsalRootGanglion | 6.85 | |
| FetalThyroid | 5.15 | |
| Fetalbrain | 4.95 | |
| Fetalliver | 4.65 | |
| Fetallung | 4.3 | |
| GlobusPallidus | 5.1 | |
| Heart | 6.6 | |
| Hypothalamus | 5.55 | |
| Kidney | 4.15 | |
| Leukemia_chronicMyelogenousK-562 | 5.4 | |
| Leukemia_promyelocytic-HL-60 | 5.1 | |
| Leukemialymphoblastic(MOLT-4) | 5.8 | |
| Liver | 6.9 | |
| Lung | 6.4 | |
| Lymphnode | 4.45 | |
| Lymphoma_burkitts(Daudi) | 7.95 | |
| Lymphoma_burkitts(Raji) | 16.05 | |
| MedullaOblongata | 4.6 | |
| OccipitalLobe | 4.45 | |
| OlfactoryBulb | 5.05 | |
| Ovary | 3.45 | |
| Pancreas | 4.5 | |
| PancreaticIslet | 5.35 | |
| ParietalLobe | 5.2 | |
| Pituitary | 6.05 | |
| Placenta | 5.95 | |
| Pons | 5.1 | |
| PrefrontalCortex | 5.9 | |
| Prostate | 6.1 | |
| Salivarygland | 4 | |
| SkeletalMuscle | 6 | |
| Skin | 4.85 | |
| SmoothMuscle | 5.9 | |
| Spinalcord | 5.55 | |
| SubthalamicNucleus | 4.75 | |
| SuperiorCervicalGanglion | 5.9 | |
| TemporalLobe | 4.7 | |
| Testis | 4.4 | |
| TestisGermCell | 4.25 | |
| TestisIntersitial | 4.35 | |
| TestisLeydigCell | 5 | |
| TestisSeminiferousTubule | 4.5 | |
| Thalamus | 5.25 | |
| Thymus | 4.05 | |
| Thyroid | 6.4 | |
| Tongue | 5.05 | |
| Tonsil | 5.55 | |
| Trachea | 4.15 | |
| TrigeminalGanglion | 5.15 | |
| Uterus | 4.2 | |
| UterusCorpus | 4.6 | |
| WholeBlood | 4.95 | |
| Wholebrain | 4.1 | |
| colon | 4.15 | |
| pineal_day | 6.04 | |
| pineal_night | 5.88 | |
| retina | 5.75 | |
| small_intestine | 4.1 | |
- Probe name: CUST_15499_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.16 ± 0.86 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 1.58 ± 0.36 | |
| Basal Part of Pons | 1.82 ± 0.63 | |
| Cerebellar Cortex | 1.81 ± 0.67 | |
| Cerebellar Nuclei | 1.96 ± 0.71 | |
| Claustrum | 2.4 ± 0.67 | |
| Epithalamus | 1.23 ± 0.78 | |
| Frontal Lobe | 1.72 ± 0.75 | |
| Globus Pallidus | 1.77 ± 0.54 | |
| Hypothalamus | 1.84 ± 0.63 | |
| Insula | 1.17 ± 0.51 | |
| Limbic Lobe | 1.77 ± 0.66 | |
| Mesencephalon | 1.86 ± 0.77 | |
| Myelencephalon | 1.76 ± 0.68 | |
| Occipital Lobe | 1.76 ± 0.7 | |
| Parietal Lobe | 1.77 ± 0.62 | |
| Pontine Tegmentum | 1.74 ± 0.7 | |
| Striatum | 1.84 ± 0.74 | |
| Subthalamus | 1.75 ± 0.72 | |
| Temporal Lobe | 1.66 ± 0.67 | |
| Thalamus | 1.69 ± 0.64 | |
| White Matter | 1.81 ± 0.5 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Traf2 | CB | Cerebellum | 66.02 | |
| 82.33 | | |||
| Traf2 | CTX | Cerebral cortex | 84.9 | |
| 50.3 | | |||
| Traf2 | HIP | Hippocampal region | 62.27 | |
| 66.18 | | |||
| Traf2 | HPF | Hippocampal formation | 83.17 | |
| 71.83 | | |||
| Traf2 | HY | Hypothalamus | 40.09 | |
| 24.26 | | |||
| Traf2 | LSX | Lateral septal complex | 24.78 | |
| 10.54 | | |||
| Traf2 | MB | Midbrain | 42.91 | |
| 29.51 | | |||
| Traf2 | MY | Medulla | 85.43 | |
| 80.6 | | |||
| Traf2 | OLF | Olfactory bulb | 82.63 | |
| 65.6 | | |||
| Traf2 | P | Pons | 74.39 | |
| 64.06 | | |||
| Traf2 | PAL | Pallidum | 39.51 | |
| 29.57 | | |||
| Traf2 | RHP | Retrohippocampal region | 100 | |
| 78.24 | | |||
| Traf2 | sAMY | Striatum-like amygdalar nuclei | 41.29 | |
| 24.29 | | |||
| Traf2 | STR | Striatum | 32.57 | |
| 17.07 | | |||
| Traf2 | STRd | Striatum dorsal region | 23.64 | |
| 10.74 | | |||
| Traf2 | STRv | Striatum ventral region | 59.66 | |
| 33.54 | | |||
| Traf2 | TH | Thalamus | 49.98 | |
| 32.97 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00040761 | 9 | 151 | 159 | HLEHECPER | Peptide Atlas |