AutismKB 2.0

Annotation Detail for C4B


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Basic Information Top
Gene Symbol:C4B ( C4B1,C4B12,C4B2,C4B3,C4B5,C4F,CH,CO4,CPAMD3,FLJ60561,MGC164979 )
Gene Full Name: complement component 4B (Chido blood group)
Band: 6p21.33
Quick LinksEntrez ID:721; OMIM: 120820; Uniprot ID:CO4B_HUMAN; ENSEMBL ID: ENSG00000224389; HGNC ID: 1324
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult48 / 193912124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma7 / 10688365
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor6 / 9635962
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal70 / 336030720
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder3 / 29757100
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain23 / 110098920
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye9 / 21105442
heart2 / 8962622
intestine2 / 2344728
kidney2 / 2117779
larynx0 / 241450 
liver20 / 20774396
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth0 / 670520 
muscle2 / 10771518
nerve4 / 15768253
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus2 / 8113124
thyroid2 / 4747342
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214428_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts13
Adipocyte43.15
AdrenalCortex657.4
Adrenalgland522.2
Amygdala135.3
Appendix149.25
AtrioventricularNode149.2
BDCA4+_DentriticCells11.85
Bonemarrow44
BronchialEpithelialCells19.15
CD105+_Endothelial221.85
CD14+_Monocytes14.4
CD19+_BCells(neg._sel.)13.4
CD33+_Myeloid13.35
CD34+50.35
CD4+_Tcells11.25
CD56+_NKCells11.8
CD71+_EarlyErythroid11.85
CD8+_Tcells10.8
CardiacMyocytes13.35
Caudatenucleus146.2
Cerebellum60.9
CerebellumPeduncles107.7
CiliaryGanglion189.5
CingulateCortex87.5
Colorectaladenocarcinoma11.9
DorsalRootGanglion88.1
FetalThyroid455.05
Fetalbrain37.2
Fetalliver149.65
Fetallung172.6
GlobusPallidus42.55
Heart298.45
Hypothalamus370.75
Kidney269.95
Leukemia_chronicMyelogenousK-56210.15
Leukemia_promyelocytic-HL-6013.6
Leukemialymphoblastic(MOLT-4)11
Liver5022.8
Lung285.1
Lymphnode175.9
Lymphoma_burkitts(Daudi)35.5
Lymphoma_burkitts(Raji)29.45
MedullaOblongata51.95
OccipitalLobe40.95
OlfactoryBulb299
Ovary154.25
Pancreas128.35
PancreaticIslet387.45
ParietalLobe25.85
Pituitary229.4
Placenta15.55
Pons109.8
PrefrontalCortex210.4
Prostate121.05
Salivarygland194
SkeletalMuscle69.5
Skin13.6
SmoothMuscle12.45
Spinalcord591.7
SubthalamicNucleus34.05
SuperiorCervicalGanglion227.8
TemporalLobe42.55
Testis40.15
TestisGermCell18.35
TestisIntersitial34.65
TestisLeydigCell22.4
TestisSeminiferousTubule62.2
Thalamus249.2
Thymus216.4
Thyroid506.35
Tongue30.9
Tonsil85.1
Trachea33.5
TrigeminalGanglion200.75
Uterus145.85
UterusCorpus152
WholeBlood12.7
Wholebrain78.15
colon34.75
pineal_day475.14
pineal_night386.68
retina634.725
small_intestine32.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
C4bCBCerebellum9.91
14.28
C4bCTXCerebral cortex5.1
4.79
C4bHIPHippocampal region15.38
16.58
C4bHPFHippocampal formation11.45
12.66
C4bHYHypothalamus9.87
9.47
C4bLSXLateral septal complex18.86
21.51
C4bMBMidbrain7.68
15.98
C4bMYMedulla7.39
10.11
C4bOLFOlfactory bulb22.15
19.72
C4bPPons12.53
16.13
C4bPALPallidum10.15
9.32
C4bRHPRetrohippocampal region5.63
7.39
C4bsAMYStriatum-like amygdalar nuclei6.46
7.97
C4bSTRStriatum7.91
8
C4bSTRdStriatum dorsal region5.26
5.38
C4bSTRvStriatum ventral region9.9
8.04
C4bTHThalamus6.79
8.17
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00024009 11 1062 1072 ADGSYAAWLSR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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