AutismKB 2.0

Annotation Detail for TRPS1


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Basic Information Top
Gene Symbol:TRPS1 ( GC79,LGCR,MGC134928 )
Gene Full Name: trichorhinophalangeal syndrome I
Band: 8q23.3
Quick LinksEntrez ID:7227; OMIM: 604386; Uniprot ID:TRPS1_HUMAN; ENSEMBL ID: ENSG00000104447; HGNC ID: 12340
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus25 / 56401244
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult66 / 193912134
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor22 / 94178233
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor3 / 13630222
kidney tumor3 / 6895943
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal78 / 336030723
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer6 / 10268058
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor10 / 90257110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain24 / 110098921
cervix0 / 481710 
connective tissue3 / 14925520
ear2 / 16212123
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye4 / 21105418
heart3 / 8962633
intestine5 / 23447221
kidney10 / 21177747
larynx1 / 2414541
liver2 / 2077439
lung2 / 3369745
lymph0 / 442700 
lymph node1 / 9161010
mammary gland39 / 153271254
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate18 / 18934595
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach2 / 9661920
testis1 / 3304423
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus12 / 23287851
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218502_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.95
Adipocyte9.05
AdrenalCortex14.25
Adrenalgland8.8
Amygdala13.15
Appendix13.2
AtrioventricularNode18.6
BDCA4+_DentriticCells8.2
Bonemarrow10.65
BronchialEpithelialCells8.2
CD105+_Endothelial9.15
CD14+_Monocytes12.1
CD19+_BCells(neg._sel.)9.5
CD33+_Myeloid14.3
CD34+10.45
CD4+_Tcells8.55
CD56+_NKCells9.45
CD71+_EarlyErythroid9.3
CD8+_Tcells8.35
CardiacMyocytes20.3
Caudatenucleus12.2
Cerebellum7.7
CerebellumPeduncles12.55
CiliaryGanglion20.65
CingulateCortex30.65
Colorectaladenocarcinoma8.8
DorsalRootGanglion11.9
FetalThyroid10.9
Fetalbrain9.8
Fetalliver7.3
Fetallung6.95
GlobusPallidus8.55
Heart12.7
Hypothalamus10.8
Kidney9.4
Leukemia_chronicMyelogenousK-5627.95
Leukemia_promyelocytic-HL-608.2
Leukemialymphoblastic(MOLT-4)6.6
Liver13.65
Lung9.55
Lymphnode7.2
Lymphoma_burkitts(Daudi)12.95
Lymphoma_burkitts(Raji)13.25
MedullaOblongata14.3
OccipitalLobe16.55
OlfactoryBulb8.95
Ovary8.35
Pancreas15.25
PancreaticIslet10.25
ParietalLobe14.5
Pituitary11.45
Placenta8.5
Pons10.05
PrefrontalCortex29.15
Prostate11.85
Salivarygland10.55
SkeletalMuscle13.7
Skin13.6
SmoothMuscle11.15
Spinalcord18.3
SubthalamicNucleus13.1
SuperiorCervicalGanglion23.9
TemporalLobe10.4
Testis7.55
TestisGermCell6.7
TestisIntersitial8.25
TestisLeydigCell10.3
TestisSeminiferousTubule8.25
Thalamus12.35
Thymus6.4
Thyroid10.75
Tongue16.55
Tonsil11.2
Trachea8.1
TrigeminalGanglion14.25
Uterus20
UterusCorpus10.95
WholeBlood10.4
Wholebrain7
colon8.55
pineal_day12.92
pineal_night12.46
retina12.5
small_intestine8.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P106980
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.03 ± 0.94
Basal Forebrain1.42 ± 0.3
Basal Part of Pons1.24 ± 0.46
Cerebellar Cortex1.24 ± 0.44
Cerebellar Nuclei1.86 ± 0.72
Claustrum2.3 ± 0.68
Epithalamus1.87 ± 0.55
Frontal Lobe1.65 ± 0.61
Globus Pallidus2.78 ± 0.61
Hypothalamus1.62 ± 0.67
Insula1.47 ± 0.62
Limbic Lobe1.59 ± 0.69
Mesencephalon1.88 ± 0.75
Myelencephalon1.74 ± 0.63
Occipital Lobe1.67 ± 0.62
Parietal Lobe1.75 ± 0.67
Pontine Tegmentum1.75 ± 0.61
Striatum2.17 ± 0.58
Subthalamus1.78 ± 0.51
Temporal Lobe1.52 ± 0.65
Thalamus1.8 ± 0.63
White Matter2.11 ± 0.42
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Trps1CBCerebellum3.82
3.32
Trps1CTXCerebral cortex5.52
3.44
Trps1HIPHippocampal region24.65
32.98
Trps1HPFHippocampal formation27.09
30.89
Trps1HYHypothalamus1.56
0.92
Trps1LSXLateral septal complex1.53
0.87
Trps1MBMidbrain2.94
1.88
Trps1MYMedulla3.57
2.44
Trps1OLFOlfactory bulb33.84
20.51
Trps1PPons4.15
3.6
Trps1PALPallidum2.95
1.72
Trps1RHPRetrohippocampal region32.31
29.37
Trps1sAMYStriatum-like amygdalar nuclei2.58
1.68
Trps1STRStriatum10.97
5.76
Trps1STRdStriatum dorsal region5.26
2.78
Trps1STRvStriatum ventral region40.75
19.24
Trps1THThalamus17.95
8.36
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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