Annotation Detail for TSC2
Basic Information Top
Gene Symbol: | TSC2 ( FLJ43106,LAM,TSC4 ) |
---|---|
Gene Full Name: | tuberous sclerosis 2 |
Band: | 16p13.3 |
Quick Links | Entrez ID:7249; OMIM: 191092; Uniprot ID:TSC2_HUMAN; ENSEMBL ID: ENSG00000103197; HGNC ID: 12363 |
Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.90303
Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
---|---|---|---|
embryoid body | 7 / 70761 | 98 | |
blastocyst | 10 / 62319 | 160 | |
fetus | 37 / 564012 | 65 | |
neonate | 1 / 31097 | 32 | |
infant | 2 / 23620 | 84 | |
juvenile | 6 / 55556 | 107 | |
adult | 175 / 1939121 | 90 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 215735_s_at
Cell line | Expression level | Expression bar |
---|---|---|
721_B_lymphoblasts | 40.75 | |
Adipocyte | 17.05 | |
AdrenalCortex | 16 | |
Adrenalgland | 16.5 | |
Amygdala | 62.35 | |
Appendix | 16.1 | |
AtrioventricularNode | 11.65 | |
BDCA4+_DentriticCells | 45.55 | |
Bonemarrow | 15.6 | |
BronchialEpithelialCells | 13.95 | |
CD105+_Endothelial | 24.7 | |
CD14+_Monocytes | 27.3 | |
CD19+_BCells(neg._sel.) | 20.7 | |
CD33+_Myeloid | 33.8 | |
CD34+ | 29.85 | |
CD4+_Tcells | 34.6 | |
CD56+_NKCells | 48.1 | |
CD71+_EarlyErythroid | 19.55 | |
CD8+_Tcells | 55.9 | |
CardiacMyocytes | 26.2 | |
Caudatenucleus | 25.4 | |
Cerebellum | 37.8 | |
CerebellumPeduncles | 33.3 | |
CiliaryGanglion | 7.65 | |
CingulateCortex | 18.2 | |
Colorectaladenocarcinoma | 26.95 | |
DorsalRootGanglion | 12.15 | |
FetalThyroid | 41.45 | |
Fetalbrain | 66.9 | |
Fetalliver | 13.75 | |
Fetallung | 24.25 | |
GlobusPallidus | 12.55 | |
Heart | 74.1 | |
Hypothalamus | 26.1 | |
Kidney | 12.5 | |
Leukemia_chronicMyelogenousK-562 | 15.15 | |
Leukemia_promyelocytic-HL-60 | 13.45 | |
Leukemialymphoblastic(MOLT-4) | 24.7 | |
Liver | 23.9 | |
Lung | 42.3 | |
Lymphnode | 18.35 | |
Lymphoma_burkitts(Daudi) | 19.9 | |
Lymphoma_burkitts(Raji) | 30.15 | |
MedullaOblongata | 17.1 | |
OccipitalLobe | 17.7 | |
OlfactoryBulb | 12.8 | |
Ovary | 12.25 | |
Pancreas | 13.3 | |
PancreaticIslet | 20.05 | |
ParietalLobe | 19.5 | |
Pituitary | 25.65 | |
Placenta | 19.65 | |
Pons | 16 | |
PrefrontalCortex | 42.65 | |
Prostate | 29.75 | |
Salivarygland | 12.1 | |
SkeletalMuscle | 18.2 | |
Skin | 11.85 | |
SmoothMuscle | 22.55 | |
Spinalcord | 16.95 | |
SubthalamicNucleus | 14.2 | |
SuperiorCervicalGanglion | 14.8 | |
TemporalLobe | 15.3 | |
Testis | 25.65 | |
TestisGermCell | 64 | |
TestisIntersitial | 30.85 | |
TestisLeydigCell | 20.05 | |
TestisSeminiferousTubule | 28.15 | |
Thalamus | 24.45 | |
Thymus | 58.45 | |
Thyroid | 180.65 | |
Tongue | 15.2 | |
Tonsil | 16 | |
Trachea | 15.75 | |
TrigeminalGanglion | 13.65 | |
Uterus | 46 | |
UterusCorpus | 14.1 | |
WholeBlood | 23.35 | |
Wholebrain | 42.15 | |
colon | 15.65 | |
pineal_day | 106.28 | |
pineal_night | 90.68 | |
retina | 52.05 | |
small_intestine | 15.3 |
Human Whole Brain Microarrayview in Allen Brain Atlas
- Probe name: CUST_662_PI416408490
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue | Expression(mean ± stddev) | Expression Bar |
---|---|---|
Amygdala | 4.39 ± 0.76 | |
Basal Forebrain | 3.83 ± 0.37 | |
Basal Part of Pons | 4.12 ± 0.6 | |
Cerebellar Cortex | 3.79 ± 0.81 | |
Cerebellar Nuclei | 3.72 ± 0.65 | |
Claustrum | 4.69 ± 1.01 | |
Epithalamus | 3.35 ± 0.42 | |
Frontal Lobe | 3.83 ± 0.61 | |
Globus Pallidus | 3.95 ± 0.51 | |
Hypothalamus | 3.14 ± 0.97 | |
Insula | 3.68 ± 0.32 | |
Limbic Lobe | 4.11 ± 0.6 | |
Mesencephalon | 3.99 ± 0.57 | |
Myelencephalon | 3.92 ± 0.69 | |
Occipital Lobe | 4.25 ± 0.71 | |
Parietal Lobe | 3.97 ± 0.72 | |
Pontine Tegmentum | 3.9 ± 0.8 | |
Striatum | 4.18 ± 0.58 | |
Subthalamus | 3.34 ± 0.49 | |
Temporal Lobe | 3.81 ± 0.7 | |
Thalamus | 4 ± 0.61 | |
White Matter | 5.07 ± 0.84 |
Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
---|---|---|---|---|
Tsc2 | CB | Cerebellum | 48.92 | |
30.33 | ||||
Tsc2 | CTX | Cerebral cortex | 50.43 | |
46.1 | ||||
Tsc2 | HIP | Hippocampal region | 46.37 | |
53.09 | ||||
Tsc2 | HPF | Hippocampal formation | 55.32 | |
52.02 | ||||
Tsc2 | HY | Hypothalamus | 50.09 | |
29.63 | ||||
Tsc2 | LSX | Lateral septal complex | 50.09 | |
31.78 | ||||
Tsc2 | MB | Midbrain | 35.26 | |
24.86 | ||||
Tsc2 | MY | Medulla | 45.55 | |
36.78 | ||||
Tsc2 | OLF | Olfactory bulb | 50.52 | |
50.29 | ||||
Tsc2 | P | Pons | 30.65 | |
26.52 | ||||
Tsc2 | PAL | Pallidum | 45.98 | |
31.3 | ||||
Tsc2 | RHP | Retrohippocampal region | 50.43 | |
50.21 | ||||
Tsc2 | sAMY | Striatum-like amygdalar nuclei | 50.13 | |
32.85 | ||||
Tsc2 | STR | Striatum | 50.31 | |
31.8 | ||||
Tsc2 | STRd | Striatum dorsal region | 50.43 | |
29.71 | ||||
Tsc2 | STRv | Striatum ventral region | 50.12 | |
37.53 | ||||
Tsc2 | TH | Thalamus | 43.19 | |
28.34 |
Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
---|---|---|---|---|---|
PAp00097033 | 25 | 382 | 406 | TIVHDLLTTVEELCDQNEFHGSQER | Peptide Atlas |