AutismKB 2.0

Annotation Detail for TSSC1


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Basic Information Top
Gene Symbol:TSSC1 ( - )
Gene Full Name: tumor suppressing subtransferable candidate 1
Band: 2p25.3
Quick LinksEntrez ID:7260; OMIM: 608998; Uniprot ID:TSSC1_HUMAN; ENSEMBL ID: ENSG00000032389; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus41 / 56401272
neonate1 / 3109732
infant3 / 23620127
juvenile6 / 55556107
adult133 / 193912168
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor13 / 94178138
cervical tumor5 / 34366145
chondrosarcoma4 / 8282348
colorectal tumor5 / 11424643
esophageal tumor1 / 1729057
gastrointestinal tumor7 / 11936958
germ cell tumor21 / 26384579
glioma11 / 106883102
head and neck tumor4 / 13630229
kidney tumor0 / 689590 
leukemia9 / 9584293
liver tumor6 / 9635962
lung tumor4 / 10312738
lymphoma11 / 71755153
non-neoplasia6 / 9725061
normal198 / 336030758
ovarian tumor4 / 7668252
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS18 / 125680143
prostate cancer5 / 10268048
retinoblastoma8 / 46356172
skin tumor8 / 12494964
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood8 / 12347864
bone4 / 7165555
bone marrow4 / 4880181
brain98 / 110098989
cervix15 / 48171311
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus1 / 2020949
eye10 / 21105447
heart3 / 8962633
intestine16 / 23447268
kidney11 / 21177751
larynx1 / 2414541
liver8 / 20774338
lung17 / 33697450
lymph1 / 4427022
lymph node4 / 9161043
mammary gland15 / 15327197
mouth1 / 6705214
muscle6 / 10771555
nerve0 / 157680 
ovary4 / 10205139
pancreas4 / 21481218
parathyroid3 / 20539146
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta14 / 28082549
prostate7 / 18934536
salivary gland0 / 201550 
skin22 / 210574104
spleen0 / 539520 
stomach7 / 9661972
testis25 / 33044275
thymus3 / 8113136
thyroid1 / 4747321
tonsil1 / 1699958
trachea2 / 5241338
umbilical cord1 / 1368073
uterus13 / 23287855
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217968_at
Cell line Expression level Expression bar
721_B_lymphoblasts75.55
Adipocyte6.5
AdrenalCortex7.1
Adrenalgland5.9
Amygdala8.95
Appendix7
AtrioventricularNode5.15
BDCA4+_DentriticCells47.9
Bonemarrow6.75
BronchialEpithelialCells8.95
CD105+_Endothelial13
CD14+_Monocytes7.75
CD19+_BCells(neg._sel.)14.1
CD33+_Myeloid11.45
CD34+34.65
CD4+_Tcells15.15
CD56+_NKCells17.4
CD71+_EarlyErythroid6.5
CD8+_Tcells19.4
CardiacMyocytes8.6
Caudatenucleus9.25
Cerebellum10.35
CerebellumPeduncles11.8
CiliaryGanglion4.75
CingulateCortex8.45
Colorectaladenocarcinoma9.25
DorsalRootGanglion5.2
FetalThyroid6.9
Fetalbrain7.35
Fetalliver5.75
Fetallung4.7
GlobusPallidus5
Heart8.05
Hypothalamus9.05
Kidney5.75
Leukemia_chronicMyelogenousK-5627.25
Leukemia_promyelocytic-HL-6010.2
Leukemialymphoblastic(MOLT-4)6.85
Liver9.1
Lung7.2
Lymphnode5.5
Lymphoma_burkitts(Daudi)14.85
Lymphoma_burkitts(Raji)9.55
MedullaOblongata7
OccipitalLobe6.4
OlfactoryBulb5.15
Ovary4.4
Pancreas4.15
PancreaticIslet7.15
ParietalLobe7.3
Pituitary12.1
Placenta5.75
Pons8.9
PrefrontalCortex8.05
Prostate7.4
Salivarygland4.8
SkeletalMuscle7.7
Skin5.25
SmoothMuscle7.7
Spinalcord7.35
SubthalamicNucleus6.3
SuperiorCervicalGanglion8.3
TemporalLobe7.45
Testis8.45
TestisGermCell5.3
TestisIntersitial5.85
TestisLeydigCell6.8
TestisSeminiferousTubule5.9
Thalamus8.3
Thymus6.3
Thyroid11.3
Tongue6.75
Tonsil6.4
Trachea5.65
TrigeminalGanglion7.05
Uterus4.65
UterusCorpus6.1
WholeBlood6.15
Wholebrain37.6
colon6.85
pineal_day15.2
pineal_night17.22
retina8.3
small_intestine6.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8782_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.77 ± 0.59
Basal Forebrain4.52 ± 0.47
Basal Part of Pons5.05 ± 0.59
Cerebellar Cortex5.17 ± 0.42
Cerebellar Nuclei4.7 ± 0.83
Claustrum4.1 ± 0.74
Epithalamus4.99 ± 0.32
Frontal Lobe4.93 ± 0.6
Globus Pallidus3.81 ± 0.34
Hypothalamus4.65 ± 0.79
Insula5.04 ± 0.46
Limbic Lobe4.73 ± 0.6
Mesencephalon4.63 ± 0.58
Myelencephalon4.64 ± 0.63
Occipital Lobe4.3 ± 0.56
Parietal Lobe4.58 ± 0.57
Pontine Tegmentum4.66 ± 0.69
Striatum4.22 ± 0.58
Subthalamus4.23 ± 0.62
Temporal Lobe4.99 ± 0.56
Thalamus4.59 ± 0.73
White Matter3.86 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tssc1CBCerebellum19.04
19.91
Tssc1CTXCerebral cortex90.99
77.76
Tssc1HIPHippocampal region47.09
58.18
Tssc1HPFHippocampal formation59.34
62.71
Tssc1HYHypothalamus38.29
29.03
Tssc1LSXLateral septal complex39.88
28.37
Tssc1MBMidbrain38.6
33.97
Tssc1MYMedulla49.79
53.55
Tssc1OLFOlfactory bulb79.53
72.54
Tssc1PPons43.98
47.53
Tssc1PALPallidum30.37
28.11
Tssc1RHPRetrohippocampal region90.28
76.33
Tssc1sAMYStriatum-like amygdalar nuclei62.86
49.97
Tssc1STRStriatum35.03
26.51
Tssc1STRdStriatum dorsal region27.06
20.44
Tssc1STRvStriatum ventral region47.26
34.13
Tssc1THThalamus34.78
28.28
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00028708 19 192 210 WSPHHNCTQVATANDTTLR Peptide Atlas
TSSC1_HUMAN_1 16 1 16 MEDDAPVIYGLEFQAR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018