Annotation Detail for TTC1
Basic Information Top
| Gene Symbol: | TTC1 ( FLJ46404,TPR1 ) |
|---|---|
| Gene Full Name: | tetratricopeptide repeat domain 1 |
| Band: | 5q33.3 |
| Quick Links | Entrez ID:7265; OMIM: 601963; Uniprot ID:TTC1_HUMAN; ENSEMBL ID: ENSG00000113312; HGNC ID: 12391 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.519718
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 1 / 62319 | 16 | |
| fetus | 31 / 564012 | 54 |  |
| neonate | 3 / 31097 | 96 | |
| infant | 1 / 23620 | 42 | |
| juvenile | 6 / 55556 | 107 | |
| adult | 169 / 1939121 | 87 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 3 / 12794 | 234 |  |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 4 / 94178 | 42 | |
| cervical tumor | 4 / 34366 | 116 | |
| chondrosarcoma | 15 / 82823 | 181 | |
| colorectal tumor | 16 / 114246 | 140 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 11 / 119369 | 92 | |
| germ cell tumor | 15 / 263845 | 56 | |
| glioma | 14 / 106883 | 130 | |
| head and neck tumor | 10 / 136302 | 73 | |
| kidney tumor | 2 / 68959 | 29 | |
| leukemia | 12 / 95842 | 125 | |
| liver tumor | 10 / 96359 | 103 | |
| lung tumor | 7 / 103127 | 67 | |
| lymphoma | 4 / 71755 | 55 | |
| non-neoplasia | 6 / 97250 | 61 | |
| normal | 204 / 3360307 | 60 | |
| ovarian tumor | 14 / 76682 | 182 | |
| pancreatic tumor | 4 / 104616 | 38 | |
| primitive neuroectodermal tumor of the CNS | 9 / 125680 | 71 | |
| prostate cancer | 4 / 102680 | 38 | |
| retinoblastoma | 6 / 46356 | 129 | |
| skin tumor | 21 / 124949 | 168 | |
| soft tissue/muscle tissue tumor | 20 / 125191 | 159 | |
| uterine tumor | 9 / 90257 | 99 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 4 / 33197 | 120 | |
| ascites | 3 / 40015 | 74 | |
| bladder | 0 / 29757 | 0 | |
| blood | 19 / 123478 | 153 | |
| bone | 17 / 71655 | 237 | |
| bone marrow | 3 / 48801 | 61 | |
| brain | 51 / 1100989 | 46 | |
| cervix | 7 / 48171 | 145 | |
| connective tissue | 23 / 149255 | 154 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 9 / 215722 | 41 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 14 / 211054 | 66 | |
| heart | 7 / 89626 | 78 | |
| intestine | 23 / 234472 | 98 | |
| kidney | 10 / 211777 | 47 | |
| larynx | 1 / 24145 | 41 | |
| liver | 20 / 207743 | 96 | |
| lung | 31 / 336974 | 91 | |
| lymph | 2 / 44270 | 45 | |
| lymph node | 11 / 91610 | 120 | |
| mammary gland | 4 / 153271 | 26 | |
| mouth | 8 / 67052 | 119 | |
| muscle | 14 / 107715 | 129 | |
| nerve | 2 / 15768 | 126 | |
| ovary | 16 / 102051 | 156 | |
| pancreas | 8 / 214812 | 37 | |
| parathyroid | 4 / 20539 | 194 | |
| pharynx | 15 / 41328 | 362 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 13 / 280825 | 46 | |
| prostate | 13 / 189345 | 68 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 26 / 210574 | 123 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 11 / 96619 | 113 | |
| testis | 21 / 330442 | 63 | |
| thymus | 7 / 81131 | 86 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 1 / 52413 | 19 | |
| umbilical cord | 3 / 13680 | 219 | |
| uterus | 18 / 232878 | 77 | |
| vascular | 6 / 51780 | 115 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 201434_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 65.2 | |
| Adipocyte | 15.1 | |
| AdrenalCortex | 6.55 |  |
| Adrenalgland | 9.65 | |
| Amygdala | 28.55 | |
| Appendix | 8 | |
| AtrioventricularNode | 4.7 | |
| BDCA4+_DentriticCells | 31.25 | |
| Bonemarrow | 7.7 | |
| BronchialEpithelialCells | 32 | |
| CD105+_Endothelial | 62.95 | |
| CD14+_Monocytes | 57.4 | |
| CD19+_BCells(neg._sel.) | 65.55 | |
| CD33+_Myeloid | 52.15 | |
| CD34+ | 61.55 | |
| CD4+_Tcells | 29.95 | |
| CD56+_NKCells | 79.4 | |
| CD71+_EarlyErythroid | 47.6 | |
| CD8+_Tcells | 42 | |
| CardiacMyocytes | 10.25 | |
| Caudatenucleus | 16.45 | |
| Cerebellum | 17.3 | |
| CerebellumPeduncles | 14.7 | |
| CiliaryGanglion | 10.1 | |
| CingulateCortex | 24.25 | |
| Colorectaladenocarcinoma | 9.9 | |
| DorsalRootGanglion | 10.7 | |
| FetalThyroid | 7.6 | |
| Fetalbrain | 8.7 | |
| Fetalliver | 6.35 | |
| Fetallung | 8.95 | |
| GlobusPallidus | 23.7 | |
| Heart | 10.3 | |
| Hypothalamus | 66.75 | |
| Kidney | 5.55 | |
| Leukemia_chronicMyelogenousK-562 | 15.2 | |
| Leukemia_promyelocytic-HL-60 | 10.45 | |
| Leukemialymphoblastic(MOLT-4) | 8.8 | |
| Liver | 8.1 | |
| Lung | 7.35 | |
| Lymphnode | 10.6 | |
| Lymphoma_burkitts(Daudi) | 20 | |
| Lymphoma_burkitts(Raji) | 11 | |
| MedullaOblongata | 14.15 | |
| OccipitalLobe | 27.25 | |
| OlfactoryBulb | 11.15 | |
| Ovary | 5.25 | |
| Pancreas | 5.55 | |
| PancreaticIslet | 17.25 | |
| ParietalLobe | 16.4 | |
| Pituitary | 11.7 | |
| Placenta | 10.35 | |
| Pons | 9.35 | |
| PrefrontalCortex | 48.3 | |
| Prostate | 9.7 | |
| Salivarygland | 7.85 | |
| SkeletalMuscle | 10.35 | |
| Skin | 5.65 | |
| SmoothMuscle | 31.9 | |
| Spinalcord | 28.05 | |
| SubthalamicNucleus | 18.1 | |
| SuperiorCervicalGanglion | 6.9 | |
| TemporalLobe | 12.3 | |
| Testis | 10.7 | |
| TestisGermCell | 12.3 | |
| TestisIntersitial | 6.15 | |
| TestisLeydigCell | 6.65 | |
| TestisSeminiferousTubule | 9.25 | |
| Thalamus | 64.45 | |
| Thymus | 11.55 | |
| Thyroid | 19.05 | |
| Tongue | 12.1 | |
| Tonsil | 8.55 | |
| Trachea | 7.65 | |
| TrigeminalGanglion | 8.6 | |
| Uterus | 9.55 | |
| UterusCorpus | 8.45 | |
| WholeBlood | 39.6 | |
| Wholebrain | 34.3 | |
| colon | 7.95 | |
| pineal_day | 36.58 | |
| pineal_night | 34.9 | |
| retina | 31.05 | |
| small_intestine | 6.25 | |
- Probe name: CUST_5786_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 7.67 ± 0.34 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 7.58 ± 0.11 | |
| Basal Part of Pons | 7.99 ± 0.11 | |
| Cerebellar Cortex | 7.62 ± 0.24 | |
| Cerebellar Nuclei | 8.16 ± 0.26 | |
| Claustrum | 7.87 ± 0.31 | |
| Epithalamus | 7.31 ± 0.3 | |
| Frontal Lobe | 7.78 ± 0.31 | |
| Globus Pallidus | 8.17 ± 0.22 | |
| Hypothalamus | 7.67 ± 0.26 | |
| Insula | 7.71 ± 0.25 | |
| Limbic Lobe | 7.81 ± 0.31 | |
| Mesencephalon | 7.8 ± 0.34 | |
| Myelencephalon | 7.69 ± 0.33 | |
| Occipital Lobe | 7.65 ± 0.29 | |
| Parietal Lobe | 7.77 ± 0.24 | |
| Pontine Tegmentum | 7.73 ± 0.3 | |
| Striatum | 7.59 ± 0.28 | |
| Subthalamus | 7.93 ± 0.2 | |
| Temporal Lobe | 7.7 ± 0.27 | |
| Thalamus | 7.74 ± 0.23 | |
| White Matter | 7.98 ± 0.15 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Ttc1 | CB | Cerebellum | 75.12 | |
| 100 | | |||
| Ttc1 | CTX | Cerebral cortex | 100 | |
| 100 | | |||
| Ttc1 | HIP | Hippocampal region | 89.92 | |
| 100 | | |||
| Ttc1 | HPF | Hippocampal formation | 94.45 | |
| 100 | | |||
| Ttc1 | HY | Hypothalamus | 95.25 | |
| 90.8 | | |||
| Ttc1 | LSX | Lateral septal complex | 100 | |
| 81.1 | | |||
| Ttc1 | MB | Midbrain | 100 | |
| 100 | | |||
| Ttc1 | MY | Medulla | 90.29 | |
| 100 | | |||
| Ttc1 | OLF | Olfactory bulb | 99.74 | |
| 99.5 | | |||
| Ttc1 | P | Pons | 87.52 | |
| 100 | | |||
| Ttc1 | PAL | Pallidum | 92.64 | |
| 100 | | |||
| Ttc1 | RHP | Retrohippocampal region | 100 | |
| 100 | | |||
| Ttc1 | sAMY | Striatum-like amygdalar nuclei | 80.51 | |
| 68.33 | | |||
| Ttc1 | STR | Striatum | 91.34 | |
| 74.95 | | |||
| Ttc1 | STRd | Striatum dorsal region | 87.92 | |
| 72.44 | | |||
| Ttc1 | STRv | Striatum ventral region | 100 | |
| 84.64 | | |||
| Ttc1 | TH | Thalamus | 100 | |
| 100 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00078585 | 12 | 202 | 213 | TDKLDEALEDYK | Peptide Atlas |