AutismKB 2.0

Annotation Detail for TTF1


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Basic Information Top
Gene Symbol:TTF1 ( - )
Gene Full Name: transcription termination factor, RNA polymerase I
Band: 9q34.13
Quick LinksEntrez ID:7270; OMIM: 600777; Uniprot ID:TTF1_HUMAN; ENSEMBL ID: ENSG00000125482; HGNC ID: 12397
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus18 / 56401231
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult38 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor6 / 9417863
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor2 / 11424617
esophageal tumor3 / 17290173
gastrointestinal tumor3 / 11936925
germ cell tumor14 / 26384553
glioma1 / 1068839
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia3 / 9584231
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma2 / 7175527
non-neoplasia0 / 972500 
normal74 / 336030722
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder0 / 297570 
blood6 / 12347848
bone2 / 7165527
bone marrow0 / 488010 
brain11 / 11009899
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus3 / 20209148
eye2 / 2110549
heart0 / 896260 
intestine3 / 23447212
kidney5 / 21177723
larynx0 / 241450 
liver11 / 20774352
lung12 / 33697435
lymph0 / 442700 
lymph node2 / 9161021
mammary gland9 / 15327158
mouth3 / 6705244
muscle2 / 10771518
nerve1 / 1576863
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate8 / 18934542
salivary gland1 / 2015549
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis10 / 33044230
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus5 / 23287821
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204772_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.25
Adipocyte5.2
AdrenalCortex5.9
Adrenalgland4.7
Amygdala5.7
Appendix5.95
AtrioventricularNode4.25
BDCA4+_DentriticCells6.25
Bonemarrow5.7
BronchialEpithelialCells6.3
CD105+_Endothelial5.75
CD14+_Monocytes5.85
CD19+_BCells(neg._sel.)10.15
CD33+_Myeloid7
CD34+7.05
CD4+_Tcells6.1
CD56+_NKCells6.65
CD71+_EarlyErythroid8.55
CD8+_Tcells6.7
CardiacMyocytes7.25
Caudatenucleus4.95
Cerebellum4.45
CerebellumPeduncles6.35
CiliaryGanglion3.95
CingulateCortex5.6
Colorectaladenocarcinoma5.65
DorsalRootGanglion4.25
FetalThyroid5.3
Fetalbrain6.6
Fetalliver4.85
Fetallung4.55
GlobusPallidus4.05
Heart7.65
Hypothalamus5.95
Kidney4.55
Leukemia_chronicMyelogenousK-5625
Leukemia_promyelocytic-HL-608.6
Leukemialymphoblastic(MOLT-4)17.3
Liver7.65
Lung6.05
Lymphnode4.75
Lymphoma_burkitts(Daudi)10.25
Lymphoma_burkitts(Raji)7.9
MedullaOblongata7.85
OccipitalLobe4.95
OlfactoryBulb4.3
Ovary3.8
Pancreas4.5
PancreaticIslet6.15
ParietalLobe5.95
Pituitary6.3
Placenta5.5
Pons5.25
PrefrontalCortex7.05
Prostate6.4
Salivarygland4.4
SkeletalMuscle6.4
Skin4.3
SmoothMuscle6.95
Spinalcord5.95
SubthalamicNucleus5.05
SuperiorCervicalGanglion6.75
TemporalLobe5.25
Testis4.8
TestisGermCell4.7
TestisIntersitial4.65
TestisLeydigCell6
TestisSeminiferousTubule4.85
Thalamus6.55
Thymus4.25
Thyroid8.65
Tongue5.4
Tonsil5.4
Trachea4.6
TrigeminalGanglion5.5
Uterus4.35
UterusCorpus5.2
WholeBlood8.6
Wholebrain4.45
colon5.4
pineal_day6.96
pineal_night6.84
retina6.5
small_intestine5.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16437_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.81 ± 0.63
Basal Forebrain4.74 ± 0.38
Basal Part of Pons5.23 ± 0.39
Cerebellar Cortex5.2 ± 0.32
Cerebellar Nuclei4.82 ± 0.46
Claustrum4.48 ± 0.72
Epithalamus5.14 ± 0.34
Frontal Lobe4.98 ± 0.42
Globus Pallidus4.74 ± 0.39
Hypothalamus4.71 ± 0.55
Insula4.93 ± 0.48
Limbic Lobe4.68 ± 0.47
Mesencephalon4.93 ± 0.55
Myelencephalon4.81 ± 0.51
Occipital Lobe4.56 ± 0.51
Parietal Lobe4.86 ± 0.43
Pontine Tegmentum4.85 ± 0.49
Striatum4.73 ± 0.79
Subthalamus5.03 ± 0.3
Temporal Lobe4.97 ± 0.42
Thalamus4.87 ± 0.52
White Matter5.05 ± 0.4
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ttf1CBCerebellum1.26
1.88
Ttf1CTXCerebral cortex0.92
1.17
Ttf1HIPHippocampal region1.73
1.9
Ttf1HPFHippocampal formation1.47
1.53
Ttf1HYHypothalamus0.23
0.21
Ttf1LSXLateral septal complex0.22
0.18
Ttf1MBMidbrain1.21
2.08
Ttf1MYMedulla0.86
0.97
Ttf1OLFOlfactory bulb1.09
2.46
Ttf1PPons0.52
0.54
Ttf1PALPallidum0.39
0.5
Ttf1RHPRetrohippocampal region0.97
0.98
Ttf1sAMYStriatum-like amygdalar nuclei0.83
0.66
Ttf1STRStriatum0.41
0.46
Ttf1STRdStriatum dorsal region0.33
0.39
Ttf1STRvStriatum ventral region0.54
0.64
Ttf1THThalamus0.67
0.79
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00497324 19 457 475 LEPANEEHNVETAEDSEIR Peptide Atlas
TTF1_HUMAN_864 16 864 879 DIFYYEDDSEGEDIEK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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