AutismKB 2.0

Annotation Detail for TLCD2


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Basic Information Top
Gene Symbol:TLCD2 ( - )
Gene Full Name: TLC domain containing 2
Band: 17p13.3
Quick LinksEntrez ID:727910; OMIM: NA; Uniprot ID:TLCD2_HUMAN; ENSEMBL ID: ENSG00000185561; HGNC ID: 33522
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult19 / 19391219
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor2 / 2638457
glioma1 / 1068839
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal27 / 33603078
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain2 / 11009891
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye7 / 21105433
heart0 / 896260 
intestine1 / 2344724
kidney0 / 2117770 
larynx0 / 241450 
liver2 / 2077439
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth2 / 6705229
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland1 / 2015549
skin0 / 2105740 
spleen0 / 539520 
stomach2 / 9661920
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P503710
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.73 ± 0.59
Basal Forebrain5.29 ± 0.26
Basal Part of Pons4.74 ± 0.48
Cerebellar Cortex5.24 ± 0.43
Cerebellar Nuclei4.92 ± 0.48
Claustrum6.56 ± 0.46
Epithalamus5.57 ± 0.86
Frontal Lobe5.14 ± 0.53
Globus Pallidus5.96 ± 0.37
Hypothalamus4.85 ± 0.65
Insula5.1 ± 0.61
Limbic Lobe5.21 ± 0.55
Mesencephalon5.18 ± 0.55
Myelencephalon5.25 ± 0.57
Occipital Lobe5.03 ± 0.52
Parietal Lobe5.13 ± 0.6
Pontine Tegmentum5.17 ± 0.61
Striatum5.36 ± 0.57
Subthalamus4.99 ± 0.29
Temporal Lobe5.16 ± 0.49
Thalamus5.05 ± 0.4
White Matter5.79 ± 0.71
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
2010305C02RikCBCerebellum1.28
2.37
2010305C02RikCTXCerebral cortex1.18
1.67
2010305C02RikHIPHippocampal region0.82
1.15
2010305C02RikHPFHippocampal formation0.79
1.2
2010305C02RikHYHypothalamus0.26
0.22
2010305C02RikLSXLateral septal complex1.36
1.97
2010305C02RikMBMidbrain1.56
2.76
2010305C02RikMYMedulla4.18
5.53
2010305C02RikOLFOlfactory bulb1.73
2.59
2010305C02RikPPons1.15
1.32
2010305C02RikPALPallidum0.29
0.42
2010305C02RikRHPRetrohippocampal region0.7
0.92
2010305C02RiksAMYStriatum-like amygdalar nuclei0.41
0.72
2010305C02RikSTRStriatum0.59
0.76
2010305C02RikSTRdStriatum dorsal region0.58
0.63
2010305C02RikSTRvStriatum ventral region0.47
0.81
2010305C02RikTHThalamus0.87
1.69
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018