AutismKB 2.0

Annotation Detail for C7


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Basic Information Top
Gene Symbol:C7 ( - )
Gene Full Name: complement component 7
Band: 5p13.1
Quick LinksEntrez ID:730; OMIM: 217070; Uniprot ID:CO7_HUMAN; ENSEMBL ID: ENSG00000112936; HGNC ID: 1346
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus21 / 56401237
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult162 / 193912183
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor5 / 12794390
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor9 / 11936975
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor3 / 13630222
kidney tumor7 / 68959101
leukemia0 / 958420 
liver tumor4 / 9635941
lung tumor5 / 10312748
lymphoma1 / 7175513
non-neoplasia8 / 9725082
normal278 / 336030782
ovarian tumor15 / 76682195
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue17 / 131061297
adrenal gland25 / 33197753
ascites0 / 400150 
bladder5 / 29757168
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain27 / 110098924
cervix0 / 481710 
connective tissue5 / 14925533
ear3 / 16212185
embryonic tissue0 / 2157220 
esophagus2 / 2020998
eye1 / 2110544
heart7 / 8962678
intestine16 / 23447268
kidney35 / 211777165
larynx0 / 241450 
liver10 / 20774348
lung32 / 33697494
lymph0 / 442700 
lymph node1 / 9161010
mammary gland7 / 15327145
mouth1 / 6705214
muscle4 / 10771537
nerve3 / 15768190
ovary18 / 102051176
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx4 / 4132896
pituitary gland0 / 165850 
placenta67 / 280825238
prostate12 / 18934563
salivary gland2 / 2015599
skin0 / 2105740 
spleen7 / 53952129
stomach9 / 9661993
testis45 / 330442136
thymus29 / 81131357
thyroid11 / 47473231
tonsil0 / 169990 
trachea27 / 52413515
umbilical cord0 / 136800 
uterus80 / 232878343
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202992_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.2
Adipocyte14.4
AdrenalCortex725.85
Adrenalgland448.1
Amygdala8.05
Appendix173.85
AtrioventricularNode43.95
BDCA4+_DentriticCells7.15
Bonemarrow9.05
BronchialEpithelialCells7.75
CD105+_Endothelial9.5
CD14+_Monocytes8.55
CD19+_BCells(neg._sel.)8.45
CD33+_Myeloid9.65
CD34+9.5
CD4+_Tcells9.7
CD56+_NKCells8.35
CD71+_EarlyErythroid7.95
CD8+_Tcells8.35
CardiacMyocytes42.6
Caudatenucleus7.95
Cerebellum7.4
CerebellumPeduncles9.95
CiliaryGanglion23.35
CingulateCortex8.9
Colorectaladenocarcinoma8.7
DorsalRootGanglion16.9
FetalThyroid190.25
Fetalbrain8.85
Fetalliver7.6
Fetallung247
GlobusPallidus6.5
Heart35.1
Hypothalamus9.2
Kidney44.6
Leukemia_chronicMyelogenousK-5628
Leukemia_promyelocytic-HL-607.5
Leukemialymphoblastic(MOLT-4)7.15
Liver15.6
Lung50.7
Lymphnode343.8
Lymphoma_burkitts(Daudi)11.65
Lymphoma_burkitts(Raji)12.75
MedullaOblongata8.1
OccipitalLobe7.55
OlfactoryBulb36.4
Ovary699.35
Pancreas181.8
PancreaticIslet346.3
ParietalLobe10.4
Pituitary12.7
Placenta146.7
Pons8.95
PrefrontalCortex10.45
Prostate88.85
Salivarygland35.65
SkeletalMuscle13.1
Skin15.6
SmoothMuscle9.45
Spinalcord11.4
SubthalamicNucleus9.2
SuperiorCervicalGanglion15.7
TemporalLobe8.05
Testis12.5
TestisGermCell72.8
TestisIntersitial22.65
TestisLeydigCell58.3
TestisSeminiferousTubule22.8
Thalamus8.9
Thymus55.4
Thyroid77.65
Tongue9.6
Tonsil8.7
Trachea16.75
TrigeminalGanglion33.25
Uterus379.45
UterusCorpus10.2
WholeBlood8.65
Wholebrain7.1
colon47.6
pineal_day22.1
pineal_night80.46
retina12.575
small_intestine130.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P213857
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.23 ± 0.67
Basal Forebrain4.2 ± 0.24
Basal Part of Pons3.73 ± 0.6
Cerebellar Cortex4.25 ± 0.74
Cerebellar Nuclei5.28 ± 0.59
Claustrum4.13 ± 0.7
Epithalamus4.33 ± 0.5
Frontal Lobe4.1 ± 0.8
Globus Pallidus5.13 ± 0.59
Hypothalamus3.89 ± 0.84
Insula4.39 ± 0.63
Limbic Lobe4.28 ± 0.75
Mesencephalon4.26 ± 0.79
Myelencephalon4.44 ± 0.72
Occipital Lobe4.16 ± 0.53
Parietal Lobe4.08 ± 0.74
Pontine Tegmentum4.36 ± 0.68
Striatum4.81 ± 0.59
Subthalamus3.43 ± 0.37
Temporal Lobe4.21 ± 0.67
Thalamus4.33 ± 0.68
White Matter4.22 ± 0.76
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00025834 26 629 654 IACVLPVLMDGIQSHPQKPFYTVGEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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