AutismKB 2.0

Annotation Detail for UBE2E2


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Basic Information Top
Gene Symbol:UBE2E2 ( FLJ25157,UBCH8 )
Gene Full Name: ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)
Band: 3p24.3
Quick LinksEntrez ID:7325; OMIM: 602163; Uniprot ID:UB2E2_HUMAN; ENSEMBL ID: ENSG00000182247; HGNC ID: 12478
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus22 / 56401239
neonate1 / 3109732
infant0 / 236200 
juvenile6 / 55556107
adult82 / 193912142
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor9 / 26384534
glioma6 / 10688356
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma5 / 7175569
non-neoplasia0 / 972500 
normal111 / 336030733
ovarian tumor1 / 7668213
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor23 / 125191183
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone2 / 7165527
bone marrow1 / 4880120
brain61 / 110098955
cervix0 / 481710 
connective tissue24 / 149255160
ear4 / 16212246
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye7 / 21105433
heart0 / 896260 
intestine1 / 2344724
kidney6 / 21177728
larynx0 / 241450 
liver1 / 2077434
lung19 / 33697456
lymph0 / 442700 
lymph node2 / 9161021
mammary gland4 / 15327126
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary3 / 10205129
pancreas5 / 21481223
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta5 / 28082517
prostate8 / 18934542
salivary gland0 / 201550 
skin0 / 2105740 
spleen2 / 5395237
stomach0 / 966190 
testis10 / 33044230
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord1 / 1368073
uterus7 / 23287830
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8013_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.82 ± 0.36
Basal Forebrain5.96 ± 0.24
Basal Part of Pons6.23 ± 0.27
Cerebellar Cortex6.39 ± 0.17
Cerebellar Nuclei6.06 ± 0.16
Claustrum5.94 ± 0.47
Epithalamus6.08 ± 0.4
Frontal Lobe6.09 ± 0.26
Globus Pallidus5.89 ± 0.37
Hypothalamus6.05 ± 0.2
Insula5.98 ± 0.28
Limbic Lobe6.06 ± 0.38
Mesencephalon6.1 ± 0.34
Myelencephalon6.04 ± 0.31
Occipital Lobe6.21 ± 0.26
Parietal Lobe6.02 ± 0.37
Pontine Tegmentum5.96 ± 0.31
Striatum5.7 ± 0.29
Subthalamus5.82 ± 0.59
Temporal Lobe6.08 ± 0.29
Thalamus6.07 ± 0.3
White Matter6.77 ± 0.43
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ube2e2CBCerebellum14.68
16.64
Ube2e2CTXCerebral cortex24.69
20.11
Ube2e2HIPHippocampal region27.05
47.67
Ube2e2HPFHippocampal formation21.12
31.58
Ube2e2HYHypothalamus4.07
3.45
Ube2e2LSXLateral septal complex1.79
1.28
Ube2e2MBMidbrain4.67
4.47
Ube2e2MYMedulla11.25
11.7
Ube2e2OLFOlfactory bulb17.62
15.55
Ube2e2PPons7.57
8.21
Ube2e2PALPallidum3.93
3.6
Ube2e2RHPRetrohippocampal region10.92
9.96
Ube2e2sAMYStriatum-like amygdalar nuclei1.35
1.19
Ube2e2STRStriatum4.14
3.49
Ube2e2STRdStriatum dorsal region3.61
3.25
Ube2e2STRvStriatum ventral region8.29
6.15
Ube2e2THThalamus4.53
3.94
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00015679 18 127 144 IYHCNINSQGVICLDILK Peptide Atlas
UB2E2_HUMAN_0 0 0 0 ESVQQEPEREQVQPK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018