AutismKB 2.0

Annotation Detail for UBTF


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Basic Information Top
Gene Symbol:UBTF ( NOR-90,UBF )
Gene Full Name: upstream binding transcription factor, RNA polymerase I
Band: 17q21.31
Quick LinksEntrez ID:7343; OMIM: 600673; Uniprot ID:UBF1_HUMAN; ENSEMBL ID: ENSG00000108312; HGNC ID: 12511
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst5 / 6231980
fetus59 / 564012104
neonate1 / 3109732
infant1 / 2362042
juvenile6 / 55556107
adult145 / 193912174
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor9 / 9417895
cervical tumor4 / 34366116
chondrosarcoma10 / 82823120
colorectal tumor9 / 11424678
esophageal tumor2 / 17290115
gastrointestinal tumor11 / 11936992
germ cell tumor19 / 26384572
glioma11 / 106883102
head and neck tumor22 / 136302161
kidney tumor5 / 6895972
leukemia11 / 95842114
liver tumor6 / 9635962
lung tumor4 / 10312738
lymphoma6 / 7175583
non-neoplasia5 / 9725051
normal262 / 336030777
ovarian tumor5 / 7668265
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer20 / 102680194
retinoblastoma2 / 4635643
skin tumor11 / 12494988
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites5 / 40015124
bladder1 / 2975733
blood8 / 12347864
bone5 / 7165569
bone marrow2 / 4880140
brain109 / 110098999
cervix4 / 4817183
connective tissue11 / 14925573
ear0 / 162120 
embryonic tissue25 / 215722115
esophagus3 / 20209148
eye16 / 21105475
heart2 / 8962622
intestine18 / 23447276
kidney13 / 21177761
larynx4 / 24145165
liver10 / 20774348
lung24 / 33697471
lymph6 / 44270135
lymph node6 / 9161065
mammary gland10 / 15327165
mouth13 / 67052193
muscle8 / 10771574
nerve2 / 15768126
ovary8 / 10205178
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta13 / 28082546
prostate38 / 189345200
salivary gland3 / 20155148
skin14 / 21057466
spleen4 / 5395274
stomach6 / 9661962
testis17 / 33044251
thymus16 / 81131197
thyroid6 / 47473126
tonsil5 / 16999294
trachea4 / 5241376
umbilical cord0 / 136800 
uterus12 / 23287851
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214881_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts40.05
Adipocyte8.85
AdrenalCortex14.35
Adrenalgland8.25
Amygdala9.4
Appendix11.9
AtrioventricularNode12.25
BDCA4+_DentriticCells22.3
Bonemarrow10.7
BronchialEpithelialCells8.75
CD105+_Endothelial10.05
CD14+_Monocytes10.9
CD19+_BCells(neg._sel.)16.6
CD33+_Myeloid13.5
CD34+16.05
CD4+_Tcells44.15
CD56+_NKCells23.95
CD71+_EarlyErythroid41.55
CD8+_Tcells46.85
CardiacMyocytes17.8
Caudatenucleus8.2
Cerebellum7.85
CerebellumPeduncles13.8
CiliaryGanglion8.5
CingulateCortex10.8
Colorectaladenocarcinoma9.4
DorsalRootGanglion10.4
FetalThyroid12.5
Fetalbrain8.7
Fetalliver7.15
Fetallung5.65
GlobusPallidus8.05
Heart17.05
Hypothalamus8.4
Kidney8.5
Leukemia_chronicMyelogenousK-5627.45
Leukemia_promyelocytic-HL-608.25
Leukemialymphoblastic(MOLT-4)7.45
Liver13.65
Lung10.1
Lymphnode7.9
Lymphoma_burkitts(Daudi)12.05
Lymphoma_burkitts(Raji)14.65
MedullaOblongata8.15
OccipitalLobe8.4
OlfactoryBulb7.1
Ovary8.65
Pancreas8.8
PancreaticIslet9.55
ParietalLobe10.15
Pituitary10.25
Placenta9.65
Pons9.15
PrefrontalCortex10.85
Prostate10.95
Salivarygland7.7
SkeletalMuscle18.6
Skin11.15
SmoothMuscle10.75
Spinalcord8.85
SubthalamicNucleus10.15
SuperiorCervicalGanglion15.3
TemporalLobe8.9
Testis6.95
TestisGermCell6.95
TestisIntersitial8.2
TestisLeydigCell10.4
TestisSeminiferousTubule7.5
Thalamus9.6
Thymus19.55
Thyroid11.45
Tongue10.6
Tonsil9.3
Trachea6.75
TrigeminalGanglion17.7
Uterus7.7
UterusCorpus9.5
WholeBlood10.35
Wholebrain9.1
colon9.5
pineal_day27.26
pineal_night21.22
retina11
small_intestine8.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P100779
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.13 ± 0.36
Basal Forebrain5.98 ± 0.53
Basal Part of Pons6.07 ± 0.21
Cerebellar Cortex6.33 ± 0.25
Cerebellar Nuclei5.75 ± 0.25
Claustrum6.04 ± 0.48
Epithalamus5.9 ± 0.22
Frontal Lobe5.86 ± 0.38
Globus Pallidus5.7 ± 0.31
Hypothalamus5.48 ± 0.35
Insula5.94 ± 0.44
Limbic Lobe6.14 ± 0.4
Mesencephalon5.84 ± 0.39
Myelencephalon5.93 ± 0.41
Occipital Lobe6.16 ± 0.36
Parietal Lobe5.87 ± 0.36
Pontine Tegmentum5.83 ± 0.47
Striatum5.88 ± 0.38
Subthalamus5.2 ± 0.54
Temporal Lobe6.01 ± 0.38
Thalamus5.8 ± 0.36
White Matter5.99 ± 0.52
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
UbtfCBCerebellum100
100
UbtfCTXCerebral cortex100
100
UbtfHIPHippocampal region100
100
UbtfHPFHippocampal formation100
100
UbtfHYHypothalamus100
100
UbtfLSXLateral septal complex100
100
UbtfMBMidbrain100
100
UbtfMYMedulla99.77
100
UbtfOLFOlfactory bulb100
100
UbtfPPons89.09
100
UbtfPALPallidum100
100
UbtfRHPRetrohippocampal region100
100
UbtfsAMYStriatum-like amygdalar nuclei100
100
UbtfSTRStriatum100
100
UbtfSTRdStriatum dorsal region100
100
UbtfSTRvStriatum ventral region100
100
UbtfTHThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00002360 32 293 324 FDGRPTKPPPNSYSLYCAELMANMKDVPSTER Peptide Atlas
UBF1_HUMAN_409 13 409 421 RPVSAMFIFSEEK PRIDE
UBF1_HUMAN_424 16 424 439 QLQEERPELSESELTR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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