AutismKB 2.0

Annotation Detail for UGDH


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Basic Information Top
Gene Symbol:UGDH ( GDH,UDP-GlcDH,UDPGDH,UGD )
Gene Full Name: UDP-glucose 6-dehydrogenase
Band: 4p14
Quick LinksEntrez ID:7358; OMIM: 603370; Uniprot ID:UGDH_HUMAN; ENSEMBL ID: ENSG00000109814; HGNC ID: 12525
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst4 / 6231964
fetus20 / 56401235
neonate14 / 31097450
infant3 / 23620127
juvenile12 / 55556215
adult96 / 193912149
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma5 / 17475286
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor5 / 11424643
esophageal tumor14 / 17290809
gastrointestinal tumor9 / 11936975
germ cell tumor18 / 26384568
glioma2 / 10688318
head and neck tumor14 / 136302102
kidney tumor3 / 6895943
leukemia3 / 9584231
liver tumor18 / 96359186
lung tumor7 / 10312767
lymphoma1 / 7175513
non-neoplasia9 / 9725092
normal246 / 336030773
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer2 / 10268019
retinoblastoma2 / 4635643
skin tumor16 / 124949128
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites6 / 40015149
bladder11 / 29757369
blood6 / 12347848
bone5 / 7165569
bone marrow1 / 4880120
brain40 / 110098936
cervix2 / 4817141
connective tissue27 / 149255180
ear0 / 162120 
embryonic tissue21 / 21572297
esophagus15 / 20209742
eye5 / 21105423
heart2 / 8962622
intestine24 / 234472102
kidney25 / 211777118
larynx0 / 241450 
liver27 / 207743129
lung16 / 33697447
lymph1 / 4427022
lymph node0 / 916100 
mammary gland7 / 15327145
mouth14 / 67052208
muscle6 / 10771555
nerve1 / 1576863
ovary2 / 10205119
pancreas16 / 21481274
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta14 / 28082549
prostate5 / 18934526
salivary gland0 / 201550 
skin31 / 210574147
spleen2 / 5395237
stomach6 / 9661962
testis21 / 33044263
thymus8 / 8113198
thyroid1 / 4747321
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord2 / 13680146
uterus12 / 23287851
vascular37 / 51780714
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203343_at
Cell line Expression level Expression bar
721_B_lymphoblasts11.05
Adipocyte94.8
AdrenalCortex9.9
Adrenalgland14.95
Amygdala8.25
Appendix26.75
AtrioventricularNode9.25
BDCA4+_DentriticCells15.75
Bonemarrow7.9
BronchialEpithelialCells39.4
CD105+_Endothelial7.3
CD14+_Monocytes9.2
CD19+_BCells(neg._sel.)10.3
CD33+_Myeloid13.2
CD34+19.4
CD4+_Tcells7.6
CD56+_NKCells17.35
CD71+_EarlyErythroid6.4
CD8+_Tcells7.4
CardiacMyocytes40.75
Caudatenucleus6.65
Cerebellum5.75
CerebellumPeduncles8.85
CiliaryGanglion43.7
CingulateCortex7.85
Colorectaladenocarcinoma8.15
DorsalRootGanglion6.8
FetalThyroid8.25
Fetalbrain7.4
Fetalliver47.95
Fetallung14.4
GlobusPallidus5.95
Heart10.75
Hypothalamus7.9
Kidney11.65
Leukemia_chronicMyelogenousK-5625.4
Leukemia_promyelocytic-HL-606.45
Leukemialymphoblastic(MOLT-4)5.85
Liver14.15
Lung8.5
Lymphnode6.85
Lymphoma_burkitts(Daudi)10.65
Lymphoma_burkitts(Raji)10.2
MedullaOblongata7.5
OccipitalLobe6.65
OlfactoryBulb14.3
Ovary8.05
Pancreas16.7
PancreaticIslet121.6
ParietalLobe8.15
Pituitary11.3
Placenta13.8
Pons8
PrefrontalCortex8.95
Prostate55.25
Salivarygland6.7
SkeletalMuscle11.65
Skin7.1
SmoothMuscle93.4
Spinalcord8.8
SubthalamicNucleus8.1
SuperiorCervicalGanglion18.3
TemporalLobe7.2
Testis6.65
TestisGermCell6.35
TestisIntersitial6.25
TestisLeydigCell8
TestisSeminiferousTubule6.85
Thalamus7.75
Thymus5.15
Thyroid14.2
Tongue19.15
Tonsil7.5
Trachea9.95
TrigeminalGanglion19.55
Uterus28.1
UterusCorpus7.4
WholeBlood8
Wholebrain6.25
colon288
pineal_day17.9
pineal_night22.9
retina26.625
small_intestine114.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P167067
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.25 ± 0.42
Basal Forebrain5.09 ± 0.33
Basal Part of Pons5.06 ± 0.27
Cerebellar Cortex5.27 ± 0.26
Cerebellar Nuclei5.04 ± 0.37
Claustrum5.26 ± 0.51
Epithalamus5.06 ± 0.27
Frontal Lobe5 ± 0.35
Globus Pallidus5.43 ± 0.43
Hypothalamus5.28 ± 0.33
Insula4.95 ± 0.41
Limbic Lobe5 ± 0.38
Mesencephalon5.17 ± 0.5
Myelencephalon5.1 ± 0.41
Occipital Lobe5.43 ± 0.34
Parietal Lobe5.11 ± 0.33
Pontine Tegmentum5.23 ± 0.3
Striatum5.09 ± 0.39
Subthalamus4.93 ± 0.37
Temporal Lobe5.14 ± 0.34
Thalamus5.26 ± 0.34
White Matter5.52 ± 0.25
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
UgdhCBCerebellum4.97
6.13
UgdhCTXCerebral cortex5.82
4.32
UgdhHIPHippocampal region6.62
6.6
UgdhHPFHippocampal formation5.16
4.67
UgdhHYHypothalamus1.84
1.35
UgdhLSXLateral septal complex0.58
0.67
UgdhMBMidbrain3.74
4.19
UgdhMYMedulla5.18
6.63
UgdhOLFOlfactory bulb6.75
5.45
UgdhPPons3.21
3.29
UgdhPALPallidum2.83
2.77
UgdhRHPRetrohippocampal region2.55
1.88
UgdhsAMYStriatum-like amygdalar nuclei4.02
3.16
UgdhSTRStriatum1.32
1.14
UgdhSTRdStriatum dorsal region0.99
0.88
UgdhSTRvStriatum ventral region1.4
1.13
UgdhTHThalamus1.53
1.22
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000712 12 268 279 ASVGFGGSCFQK Peptide Atlas
UGDH_HUMAN_220 10 220 229 LAANAFLAQR PRIDE
UGDH_HUMAN_432 11 432 442 MLKPAFIFDGR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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