AutismKB 2.0

Annotation Detail for UPP1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:UPP1 ( UDRPASE,UP,UPASE,UPP )
Gene Full Name: uridine phosphorylase 1
Band: 7p12.3
Quick LinksEntrez ID:7378; OMIM: 191730; Uniprot ID:UPP1_HUMAN; ENSEMBL ID: ENSG00000183696; HGNC ID: 12576
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst5 / 6231980
fetus11 / 56401219
neonate2 / 3109764
infant1 / 2362042
juvenile1 / 5555617
adult93 / 193912147
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor2 / 3436658
chondrosarcoma9 / 82823108
colorectal tumor3 / 11424626
esophageal tumor1 / 1729057
gastrointestinal tumor13 / 119369108
germ cell tumor64 / 263845242
glioma7 / 10688365
head and neck tumor8 / 13630258
kidney tumor7 / 68959101
leukemia3 / 9584231
liver tumor2 / 9635920
lung tumor17 / 103127164
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal126 / 336030737
ovarian tumor0 / 766820 
pancreatic tumor32 / 104616305
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer8 / 10268077
retinoblastoma1 / 4635621
skin tumor52 / 124949416
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites5 / 40015124
bladder0 / 297570 
blood14 / 123478113
bone4 / 7165555
bone marrow5 / 48801102
brain19 / 110098917
cervix2 / 4817141
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue15 / 21572269
esophagus1 / 2020949
eye8 / 21105437
heart1 / 8962611
intestine9 / 23447238
kidney16 / 21177775
larynx2 / 2414582
liver4 / 20774319
lung35 / 336974103
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth1 / 6705214
muscle0 / 1077150 
nerve1 / 1576863
ovary4 / 10205139
pancreas33 / 214812153
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta54 / 280825192
prostate20 / 189345105
salivary gland3 / 20155148
skin58 / 210574275
spleen2 / 5395237
stomach18 / 96619186
testis2 / 3304426
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord2 / 13680146
uterus9 / 23287838
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203234_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.1
Adipocyte5.45
AdrenalCortex6.3
Adrenalgland4.85
Amygdala6.1
Appendix5.55
AtrioventricularNode4.3
BDCA4+_DentriticCells7.55
Bonemarrow5.75
BronchialEpithelialCells725.6
CD105+_Endothelial5.3
CD14+_Monocytes102.1
CD19+_BCells(neg._sel.)5.85
CD33+_Myeloid63.9
CD34+7.1
CD4+_Tcells61.4
CD56+_NKCells49.3
CD71+_EarlyErythroid5
CD8+_Tcells38.35
CardiacMyocytes7.05
Caudatenucleus5.2
Cerebellum4.6
CerebellumPeduncles20.75
CiliaryGanglion4
CingulateCortex11.6
Colorectaladenocarcinoma28.25
DorsalRootGanglion3.9
FetalThyroid5.45
Fetalbrain5.5
Fetalliver4.95
Fetallung10.4
GlobusPallidus4.2
Heart10.75
Hypothalamus18.15
Kidney4.6
Leukemia_chronicMyelogenousK-5624.95
Leukemia_promyelocytic-HL-605.1
Leukemialymphoblastic(MOLT-4)4.35
Liver7.7
Lung69.35
Lymphnode5.05
Lymphoma_burkitts(Daudi)6.9
Lymphoma_burkitts(Raji)10.75
MedullaOblongata9.95
OccipitalLobe4.9
OlfactoryBulb6.45
Ovary3.8
Pancreas4.5
PancreaticIslet6.2
ParietalLobe6
Pituitary6.6
Placenta102.8
Pons5.45
PrefrontalCortex30.55
Prostate6.8
Salivarygland4.45
SkeletalMuscle6.4
Skin4.4
SmoothMuscle6.4
Spinalcord6.2
SubthalamicNucleus5.2
SuperiorCervicalGanglion6.4
TemporalLobe5.25
Testis4.85
TestisGermCell4.4
TestisIntersitial4.85
TestisLeydigCell5.5
TestisSeminiferousTubule4.85
Thalamus10.15
Thymus4.25
Thyroid7.35
Tongue34.85
Tonsil5.6
Trachea4.6
TrigeminalGanglion5.7
Uterus4.6
UterusCorpus11.8
WholeBlood56.9
Wholebrain9.9
colon5.75
pineal_day29.74
pineal_night35.36
retina6.95
small_intestine5.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P351275
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.31 ± 0.47
Basal Forebrain5.78 ± 0.32
Basal Part of Pons5.75 ± 0.25
Cerebellar Cortex5.97 ± 0.33
Cerebellar Nuclei4.91 ± 0.52
Claustrum4.72 ± 0.78
Epithalamus4.9 ± 0.67
Frontal Lobe5.16 ± 0.52
Globus Pallidus4.93 ± 0.25
Hypothalamus5.59 ± 0.62
Insula5.13 ± 0.54
Limbic Lobe5.11 ± 0.51
Mesencephalon5.55 ± 0.71
Myelencephalon5.43 ± 0.6
Occipital Lobe6.16 ± 0.65
Parietal Lobe5.62 ± 0.47
Pontine Tegmentum5.25 ± 0.65
Striatum5.39 ± 0.54
Subthalamus4.94 ± 0.51
Temporal Lobe5.27 ± 0.51
Thalamus5.79 ± 0.45
White Matter4.29 ± 0.21
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Upp1CBCerebellum3.15
4.41
Upp1CTXCerebral cortex4.67
4.02
Upp1HIPHippocampal region5.28
6.09
Upp1HPFHippocampal formation4.92
5.16
Upp1HYHypothalamus0.51
0.41
Upp1LSXLateral septal complex0.43
0.51
Upp1MBMidbrain1.99
2.3
Upp1MYMedulla5.66
7.71
Upp1OLFOlfactory bulb9.24
9.06
Upp1PPons3.62
3.47
Upp1PALPallidum0.67
0.51
Upp1RHPRetrohippocampal region4.35
3.88
Upp1sAMYStriatum-like amygdalar nuclei1.22
1
Upp1STRStriatum0.97
0.84
Upp1STRdStriatum dorsal region0.97
0.87
Upp1STRvStriatum ventral region0.82
0.58
Upp1THThalamus1.69
1.68
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00133136 11 44 54 HNFPALFGDVK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved