AutismKB 2.0

Annotation Detail for UQCRB


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Basic Information Top
Gene Symbol:UQCRB ( FLJ92016,FLJ97033,QCR7,QP-C,QPC,UQBC,UQBP,UQCR6,UQPC )
Gene Full Name: ubiquinol-cytochrome c reductase binding protein
Band: 8q22.1
Quick LinksEntrez ID:7381; OMIM: 191330; Uniprot ID:QCR7_HUMAN; ENSEMBL ID: ENSG00000156467; HGNC ID: 12582
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body10 / 70761141
blastocyst3 / 6231948
fetus84 / 564012148
neonate1 / 3109732
infant0 / 236200 
juvenile7 / 55556125
adult258 / 1939121133
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor5 / 12794390
bladder carcinoma2 / 17475114
breast (mammary gland) tumor9 / 9417895
cervical tumor2 / 3436658
chondrosarcoma6 / 8282372
colorectal tumor10 / 11424687
esophageal tumor0 / 172900 
gastrointestinal tumor16 / 119369134
germ cell tumor12 / 26384545
glioma2 / 10688318
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia9 / 9584293
liver tumor8 / 9635983
lung tumor6 / 10312758
lymphoma5 / 7175569
non-neoplasia0 / 972500 
normal430 / 3360307127
ovarian tumor12 / 76682156
pancreatic tumor18 / 104616172
primitive neuroectodermal tumor of the CNS21 / 125680167
prostate cancer48 / 102680467
retinoblastoma2 / 4635643
skin tumor4 / 12494932
soft tissue/muscle tissue tumor47 / 125191375
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland6 / 33197180
ascites7 / 40015174
bladder3 / 29757100
blood7 / 12347856
bone33 / 71655460
bone marrow10 / 48801204
brain118 / 1100989107
cervix2 / 4817141
connective tissue4 / 14925526
ear10 / 16212616
embryonic tissue25 / 215722115
esophagus0 / 202090 
eye28 / 211054132
heart23 / 89626256
intestine20 / 23447285
kidney11 / 21177751
larynx0 / 241450 
liver24 / 207743115
lung21 / 33697462
lymph1 / 4427022
lymph node5 / 9161054
mammary gland13 / 15327184
mouth0 / 670520 
muscle63 / 107715584
nerve3 / 15768190
ovary15 / 102051146
pancreas24 / 214812111
parathyroid7 / 20539340
pharynx3 / 4132872
pituitary gland4 / 16585241
placenta14 / 28082549
prostate59 / 189345311
salivary gland1 / 2015549
skin7 / 21057433
spleen5 / 5395292
stomach10 / 96619103
testis8 / 33044224
thymus0 / 811310 
thyroid5 / 47473105
tonsil1 / 1699958
trachea5 / 5241395
umbilical cord1 / 1368073
uterus8 / 23287834
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209065_at
Cell line Expression level Expression bar
721_B_lymphoblasts16
Adipocyte14.95
AdrenalCortex18.75
Adrenalgland13.85
Amygdala34.65
Appendix18.9
AtrioventricularNode11.75
BDCA4+_DentriticCells19.25
Bonemarrow14.4
BronchialEpithelialCells15.2
CD105+_Endothelial14.8
CD14+_Monocytes16.5
CD19+_BCells(neg._sel.)21.75
CD33+_Myeloid17.6
CD34+16
CD4+_Tcells15.45
CD56+_NKCells17.05
CD71+_EarlyErythroid13.2
CD8+_Tcells13.15
CardiacMyocytes22.15
Caudatenucleus22.8
Cerebellum21.55
CerebellumPeduncles24.8
CiliaryGanglion7.75
CingulateCortex24.2
Colorectaladenocarcinoma15.25
DorsalRootGanglion11.7
FetalThyroid15.3
Fetalbrain28.9
Fetalliver12.7
Fetallung10.65
GlobusPallidus17.35
Heart26.95
Hypothalamus33.1
Kidney12.8
Leukemia_chronicMyelogenousK-56213.4
Leukemia_promyelocytic-HL-6030
Leukemialymphoblastic(MOLT-4)13.5
Liver22
Lung16.5
Lymphnode12.6
Lymphoma_burkitts(Daudi)21.25
Lymphoma_burkitts(Raji)24.85
MedullaOblongata37.65
OccipitalLobe16.4
OlfactoryBulb17.15
Ovary12
Pancreas12.45
PancreaticIslet16.55
ParietalLobe17.9
Pituitary30.2
Placenta11.95
Pons15.65
PrefrontalCortex38.1
Prostate17.15
Salivarygland12.9
SkeletalMuscle24.4
Skin14.15
SmoothMuscle17.65
Spinalcord18.1
SubthalamicNucleus15.5
SuperiorCervicalGanglion19.65
TemporalLobe29.55
Testis13.05
TestisGermCell10.4
TestisIntersitial10.7
TestisLeydigCell14.9
TestisSeminiferousTubule13
Thalamus20.45
Thymus11.35
Thyroid19.15
Tongue17
Tonsil13.8
Trachea13.45
TrigeminalGanglion21.1
Uterus12.25
UterusCorpus17.35
WholeBlood19.95
Wholebrain40.25
colon15.85
pineal_day46
pineal_night67.9
retina19.05
small_intestine16.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6088_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala11.32 ± 0.2
Basal Forebrain11.42 ± 0.1
Basal Part of Pons11.48 ± 0.16
Cerebellar Cortex11.12 ± 0.22
Cerebellar Nuclei11.85 ± 0.28
Claustrum11.21 ± 0.26
Epithalamus11.42 ± 0.27
Frontal Lobe11.44 ± 0.27
Globus Pallidus12.24 ± 0.25
Hypothalamus11.54 ± 0.22
Insula11.39 ± 0.26
Limbic Lobe11.12 ± 0.43
Mesencephalon11.45 ± 0.39
Myelencephalon11.3 ± 0.36
Occipital Lobe11.01 ± 0.36
Parietal Lobe11.42 ± 0.29
Pontine Tegmentum11.43 ± 0.29
Striatum11.51 ± 0.27
Subthalamus11.89 ± 0.12
Temporal Lobe11.3 ± 0.29
Thalamus11.39 ± 0.25
White Matter11.3 ± 0.52
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
UqcrbCBCerebellum43.08
77.83
UqcrbCTXCerebral cortex100
100
UqcrbHIPHippocampal region100
100
UqcrbHPFHippocampal formation99.83
100
UqcrbHYHypothalamus98.48
100
UqcrbLSXLateral septal complex100
100
UqcrbMBMidbrain89.4
97.19
UqcrbMYMedulla88.57
100
UqcrbOLFOlfactory bulb100
100
UqcrbPPons85.42
98.57
UqcrbPALPallidum99.49
100
UqcrbRHPRetrohippocampal region95.91
100
UqcrbsAMYStriatum-like amygdalar nuclei89.88
89.28
UqcrbSTRStriatum97.41
93.53
UqcrbSTRdStriatum dorsal region92.32
87.45
UqcrbSTRvStriatum ventral region100
100
UqcrbTHThalamus86.38
88.87
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00002196 18 79 96 EQWTKYEEENFYLEPYLK Peptide Atlas
QCR7_HUMAN_20 10 20 29 WYYNAAGFNK PRIDE
QCR7_HUMAN_34 15 34 48 DDTIYEDEDVKEAIR PRIDE
QCR7_HUMAN_35 15 35 49 DDTIYEDEDVKEAIR PRIDE
QCR7_HUMAN_49 10 49 58 RLPENLYNDR PRIDE
QCR7_HUMAN_50 10 50 59 RLPENLYNDR PRIDE
QCR7_HUMAN_50 9 50 58 LPENLYNDR PRIDE
QCR7_HUMAN_51 9 51 59 LPENLYNDR PRIDE
QCR7_HUMAN_66 7 66 72 ALDLNLK PRIDE
QCR7_HUMAN_78 18 78 95 EQWTKYEEENFYLEPYLK PRIDE
QCR7_HUMAN_79 18 79 96 EQWTKYEEENFYLEPYLK PRIDE
QCR7_HUMAN_84 13 84 96 YEEENFYLEPYLK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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