AutismKB 2.0

Annotation Detail for VCP


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Basic Information Top
Gene Symbol:VCP ( IBMPFD,MGC131997,MGC148092,MGC8560,TERA,p97 )
Gene Full Name: valosin-containing protein
Band: 9p13.3
Quick LinksEntrez ID:7415; OMIM: 601023; Uniprot ID:TERA_HUMAN; ENSEMBL ID: ENSG00000165280; HGNC ID: 12666
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body32 / 70761452
blastocyst41 / 62319657
fetus265 / 564012469
neonate22 / 31097707
infant7 / 23620296
juvenile28 / 55556503
adult625 / 1939121322
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor7 / 12794547
bladder carcinoma9 / 17475515
breast (mammary gland) tumor33 / 94178350
cervical tumor13 / 34366378
chondrosarcoma51 / 82823615
colorectal tumor48 / 114246420
esophageal tumor5 / 17290289
gastrointestinal tumor44 / 119369368
germ cell tumor235 / 263845890
glioma38 / 106883355
head and neck tumor148 / 1363021085
kidney tumor35 / 68959507
leukemia27 / 95842281
liver tumor37 / 96359383
lung tumor46 / 103127446
lymphoma60 / 71755836
non-neoplasia33 / 97250339
normal1393 / 3360307414
ovarian tumor20 / 76682260
pancreatic tumor45 / 104616430
primitive neuroectodermal tumor of the CNS61 / 125680485
prostate cancer66 / 102680642
retinoblastoma17 / 46356366
skin tumor61 / 124949488
soft tissue/muscle tissue tumor35 / 125191279
uterine tumor41 / 90257454
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland15 / 33197451
ascites14 / 40015349
bladder7 / 29757235
blood37 / 123478299
bone25 / 71655348
bone marrow9 / 48801184
brain645 / 1100989585
cervix18 / 48171373
connective tissue64 / 149255428
ear1 / 1621261
embryonic tissue105 / 215722486
esophagus5 / 20209247
eye57 / 211054270
heart29 / 89626323
intestine93 / 234472396
kidney98 / 211777462
larynx4 / 24145165
liver48 / 207743231
lung233 / 336974691
lymph49 / 442701106
lymph node24 / 91610261
mammary gland43 / 153271280
mouth130 / 670521938
muscle17 / 107715157
nerve2 / 15768126
ovary39 / 102051382
pancreas52 / 214812242
parathyroid5 / 20539243
pharynx4 / 4132896
pituitary gland5 / 16585301
placenta152 / 280825541
prostate90 / 189345475
salivary gland4 / 20155198
skin106 / 210574503
spleen42 / 53952778
stomach40 / 96619413
testis254 / 330442768
thymus77 / 81131949
thyroid12 / 47473252
tonsil7 / 16999411
trachea55 / 524131049
umbilical cord1 / 1368073
uterus94 / 232878403
vascular38 / 51780733
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208649_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts900.1
Adipocyte314.1
AdrenalCortex131.15
Adrenalgland171
Amygdala202.8
Appendix18.35
AtrioventricularNode25.7
BDCA4+_DentriticCells571.35
Bonemarrow140.65
BronchialEpithelialCells546.95
CD105+_Endothelial304.1
CD14+_Monocytes270.25
CD19+_BCells(neg._sel.)272.4
CD33+_Myeloid340.5
CD34+333.85
CD4+_Tcells295.75
CD56+_NKCells286.75
CD71+_EarlyErythroid416.45
CD8+_Tcells262.2
CardiacMyocytes441.4
Caudatenucleus111.15
Cerebellum140.55
CerebellumPeduncles142.5
CiliaryGanglion15.05
CingulateCortex93.25
Colorectaladenocarcinoma780.15
DorsalRootGanglion53.75
FetalThyroid191.3
Fetalbrain201.1
Fetalliver187.2
Fetallung255.45
GlobusPallidus45.8
Heart224.65
Hypothalamus331.2
Kidney96.4
Leukemia_chronicMyelogenousK-562171.7
Leukemia_promyelocytic-HL-60226.65
Leukemialymphoblastic(MOLT-4)196.1
Liver251.8
Lung519.05
Lymphnode194.45
Lymphoma_burkitts(Daudi)310.5
Lymphoma_burkitts(Raji)428.6
MedullaOblongata82.5
OccipitalLobe159.65
OlfactoryBulb92.1
Ovary98.55
Pancreas139.9
PancreaticIslet304.3
ParietalLobe111.15
Pituitary234.65
Placenta501.35
Pons78.6
PrefrontalCortex216
Prostate606.4
Salivarygland30.3
SkeletalMuscle48.45
Skin22.65
SmoothMuscle824.5
Spinalcord194.7
SubthalamicNucleus67.2
SuperiorCervicalGanglion18.8
TemporalLobe83.5
Testis209.5
TestisGermCell156.75
TestisIntersitial142.7
TestisLeydigCell120.8
TestisSeminiferousTubule96.5
Thalamus178.25
Thymus365.65
Thyroid366.35
Tongue135.35
Tonsil220.35
Trachea126.95
TrigeminalGanglion18.05
Uterus355.4
UterusCorpus86.95
WholeBlood243.35
Wholebrain319.8
colon296.9
pineal_day435.12
pineal_night388.24
retina368.2
small_intestine337.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P127828
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.52 ± 0.22
Basal Forebrain8.33 ± 0.25
Basal Part of Pons8.36 ± 0.31
Cerebellar Cortex8.36 ± 0.25
Cerebellar Nuclei8.18 ± 0.29
Claustrum8.62 ± 0.34
Epithalamus8.28 ± 0.17
Frontal Lobe8.32 ± 0.25
Globus Pallidus8.28 ± 0.19
Hypothalamus8.47 ± 0.28
Insula8.33 ± 0.22
Limbic Lobe8.57 ± 0.29
Mesencephalon8.41 ± 0.39
Myelencephalon8.41 ± 0.26
Occipital Lobe8.48 ± 0.28
Parietal Lobe8.35 ± 0.27
Pontine Tegmentum8.39 ± 0.26
Striatum8.28 ± 0.25
Subthalamus8.22 ± 0.18
Temporal Lobe8.43 ± 0.23
Thalamus8.39 ± 0.21
White Matter8.63 ± 0.35
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
VcpCBCerebellum46.35
100
VcpCTXCerebral cortex100
100
VcpHIPHippocampal region100
100
VcpHPFHippocampal formation100
100
VcpHYHypothalamus100
100
VcpLSXLateral septal complex100
100
VcpMBMidbrain100
100
VcpMYMedulla100
100
VcpOLFOlfactory bulb100
100
VcpPPons100
100
VcpPALPallidum100
100
VcpRHPRetrohippocampal region100
100
VcpsAMYStriatum-like amygdalar nuclei100
100
VcpSTRStriatum100
100
VcpSTRdStriatum dorsal region100
100
VcpSTRvStriatum ventral region100
100
VcpTHThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000423 14 530 543 AIANECQANFISIK Peptide Atlas
TERA_HUMAN_0 0 0 0 EVDIGIPDATGRLEILQIHTK PRIDE
TERA_HUMAN_0 0 0 0 IVSQLLTLMDGLK PRIDE
TERA_HUMAN_0 0 0 0 LGDVISIQPCPDVK PRIDE
TERA_HUMAN_0 0 0 0 NAPAIIFIDELDAIAPK PRIDE
TERA_HUMAN_113 34 113 146 IHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPIR PRIDE
TERA_HUMAN_113 35 113 147 IHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPIRK PRIDE
TERA_HUMAN_113 35 113 147 RIHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPIR PRIDE
TERA_HUMAN_217 14 217 230 EMVELPLRHPALFK PRIDE
TERA_HUMAN_218 8 218 225 EMVELPLR PRIDE
TERA_HUMAN_239 12 239 250 GILLYGPPGTGK PRIDE
TERA_HUMAN_239 17 239 255 GILLYGPPGTGKTLIAR PRIDE
TERA_HUMAN_25 20 25 44 LIVDEAINEDNSVVSLSQPK PRIDE
TERA_HUMAN_256 21 256 276 AVANETGAFFFLINGPEIMSK PRIDE
TERA_HUMAN_26 20 26 45 LIVDEAINEDNSVVSLSQPK PRIDE
TERA_HUMAN_278 10 278 287 LAGESESNLR PRIDE
TERA_HUMAN_287 25 287 311 KAFEEAEKNAPAIIFIDELDAIAPK PRIDE
TERA_HUMAN_288 24 288 311 AFEEAEKNAPAIIFIDELDAIAPK PRIDE
TERA_HUMAN_288 25 288 312 AFEEAEKNAPAIIFIDELDAIAPKR PRIDE
TERA_HUMAN_295 17 295 311 NAPAIIFIDELDAIAPK PRIDE
TERA_HUMAN_295 18 295 312 NAPAIIFIDELDAIAPKR PRIDE
TERA_HUMAN_296 17 296 312 NAPAIIFIDELDAIAPK PRIDE
TERA_HUMAN_322 14 322 335 RIVSQLLTLMDGLK PRIDE
TERA_HUMAN_323 13 323 335 IVSQLLTLMDGLK PRIDE
TERA_HUMAN_324 13 324 336 IVSQLLTLMDGLK PRIDE
TERA_HUMAN_338 20 338 357 AHVIVMAATNRPNSIDPALR PRIDE
TERA_HUMAN_338 21 338 358 AHVIVMAATNRPNSIDPALRR PRIDE
TERA_HUMAN_339 20 339 358 AHVIVMAATNRPNSIDPALR PRIDE
TERA_HUMAN_365 12 365 376 EVDIGIPDATGR PRIDE
TERA_HUMAN_365 21 365 385 EVDIGIPDATGRLEILQIHTK PRIDE
TERA_HUMAN_366 11 366 376 VDIGIPDATGR PRIDE
TERA_HUMAN_366 12 366 377 EVDIGIPDATGR PRIDE
TERA_HUMAN_389 35 389 423 LADDVDLEQVANETHGHVGADLAALCSEAALQAIR PRIDE
TERA_HUMAN_390 35 390 424 LADDVDLEQVANETHGHVGADLAALCSEAALQAIR PRIDE
TERA_HUMAN_45 15 45 59 MDELQLFRGDTVLLK PRIDE
TERA_HUMAN_45 8 45 52 MDELQLFR PRIDE
TERA_HUMAN_453 12 453 464 WALSQSNPSALR PRIDE
TERA_HUMAN_454 12 454 465 WALSQSNPSALR PRIDE
TERA_HUMAN_465 22 465 486 ETVVEVPQVTWEDIGGLEDVKR PRIDE
TERA_HUMAN_466 22 466 487 ETVVEVPQVTWEDIGGLEDVKR PRIDE
TERA_HUMAN_487 18 487 504 ELQELVQYPVEHPDKFLK PRIDE
TERA_HUMAN_488 15 488 502 ELQELVQYPVEHPDK PRIDE
TERA_HUMAN_512 12 512 523 GVLFYGPPGCGK PRIDE
TERA_HUMAN_529 14 529 542 AIANECQANFISIK PRIDE
TERA_HUMAN_530 14 530 543 AIANECQANFISIK PRIDE
TERA_HUMAN_543 17 543 559 GPELLTMWFGESEANVR PRIDE
TERA_HUMAN_544 17 544 560 GPELLTMWFGESEANVR PRIDE
TERA_HUMAN_544 22 544 565 GPELLTMWFGESEANVREIFDK PRIDE
TERA_HUMAN_567 17 567 583 QAAPCVLFFDELDSIAK PRIDE
TERA_HUMAN_568 17 568 584 QAAPCVLFFDELDSIAK PRIDE
TERA_HUMAN_575 11 575 585 FDELDSIAKAR PRIDE
TERA_HUMAN_576 10 576 585 DELDSIAKAR PRIDE
TERA_HUMAN_586 29 586 614 GGNIGDGGGAADRVINQILTEMDGMSTKK PRIDE
TERA_HUMAN_599 15 599 613 VINQILTEMDGMSTK PRIDE
TERA_HUMAN_599 16 599 614 VINQILTEMDGMSTKK PRIDE
TERA_HUMAN_614 24 614 637 KNVFIIGATNRPDIIDPAILRPGR PRIDE
TERA_HUMAN_615 23 615 637 NVFIIGATNRPDIIDPAILRPGR PRIDE
TERA_HUMAN_615 24 615 638 KNVFIIGATNRPDIIDPAILRPGR PRIDE
TERA_HUMAN_616 23 616 638 NVFIIGATNRPDIIDPAILRPGR PRIDE
TERA_HUMAN_638 13 638 650 LDQLIYIPLPDEK PRIDE
TERA_HUMAN_639 13 639 651 LDQLIYIPLPDEK PRIDE
TERA_HUMAN_668 9 668 676 DVDLEFLAK PRIDE
TERA_HUMAN_713 19 713 731 QTNPSAMEVEEDDPVPEIR PRIDE
TERA_HUMAN_714 19 714 732 QTNPSAMEVEEDDPVPEIR PRIDE
TERA_HUMAN_732 9 732 740 RDHFEEAMR PRIDE
TERA_HUMAN_733 8 733 740 DHFEEAMR PRIDE
TERA_HUMAN_746 8 746 753 SVSDNDIR PRIDE
TERA_HUMAN_753 13 753 765 KYEMFAQTLQQSR PRIDE
TERA_HUMAN_754 12 754 765 YEMFAQTLQQSR PRIDE
TERA_HUMAN_95 14 95 108 LGDVISIQPCPDVK PRIDE
TERA_HUMAN_96 14 96 109 LGDVISIQPCPDVK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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