AutismKB 2.0

Annotation Detail for VDAC2


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Basic Information Top
Gene Symbol:VDAC2 ( FLJ23841,POR )
Gene Full Name: voltage-dependent anion channel 2
Band: 10q22.2
Quick LinksEntrez ID:7417; OMIM: 193245; Uniprot ID:VDAC2_HUMAN; ENSEMBL ID: ENSG00000165637; HGNC ID: 12672
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body22 / 70761310
blastocyst20 / 62319320
fetus65 / 564012115
neonate2 / 3109764
infant8 / 23620338
juvenile6 / 55556107
adult302 / 1939121155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor8 / 12794625
bladder carcinoma3 / 17475171
breast (mammary gland) tumor23 / 94178244
cervical tumor12 / 34366349
chondrosarcoma20 / 82823241
colorectal tumor22 / 114246192
esophageal tumor2 / 17290115
gastrointestinal tumor40 / 119369335
germ cell tumor32 / 263845121
glioma11 / 106883102
head and neck tumor20 / 136302146
kidney tumor4 / 6895958
leukemia8 / 9584283
liver tumor20 / 96359207
lung tumor25 / 103127242
lymphoma8 / 71755111
non-neoplasia8 / 9725082
normal464 / 3360307138
ovarian tumor5 / 7668265
pancreatic tumor25 / 104616238
primitive neuroectodermal tumor of the CNS20 / 125680159
prostate cancer41 / 102680399
retinoblastoma17 / 46356366
skin tumor25 / 124949200
soft tissue/muscle tissue tumor41 / 125191327
uterine tumor18 / 90257199
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue6 / 13106457
adrenal gland9 / 33197271
ascites6 / 40015149
bladder1 / 2975733
blood10 / 12347880
bone15 / 71655209
bone marrow5 / 48801102
brain160 / 1100989145
cervix14 / 48171290
connective tissue24 / 149255160
ear3 / 16212185
embryonic tissue63 / 215722292
esophagus2 / 2020998
eye50 / 211054236
heart12 / 89626133
intestine47 / 234472200
kidney19 / 21177789
larynx1 / 2414541
liver29 / 207743139
lung70 / 336974207
lymph5 / 44270112
lymph node10 / 91610109
mammary gland27 / 153271176
mouth9 / 67052134
muscle42 / 107715389
nerve3 / 15768190
ovary6 / 10205158
pancreas43 / 214812200
parathyroid7 / 20539340
pharynx5 / 41328120
pituitary gland3 / 16585180
placenta42 / 280825149
prostate46 / 189345242
salivary gland6 / 20155297
skin45 / 210574213
spleen6 / 53952111
stomach44 / 96619455
testis36 / 330442108
thymus1 / 8113112
thyroid5 / 47473105
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord2 / 13680146
uterus43 / 232878184
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211662_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts1718.05
Adipocyte495.35
AdrenalCortex212
Adrenalgland369.35
Amygdala637.4
Appendix194.6
AtrioventricularNode166.4
BDCA4+_DentriticCells688.1
Bonemarrow181
BronchialEpithelialCells1717.25
CD105+_Endothelial590.55
CD14+_Monocytes573.45
CD19+_BCells(neg._sel.)701.65
CD33+_Myeloid874.1
CD34+1088.6
CD4+_Tcells340.1
CD56+_NKCells673.4
CD71+_EarlyErythroid288
CD8+_Tcells363
CardiacMyocytes607.95
Caudatenucleus331.95
Cerebellum384.85
CerebellumPeduncles445.65
CiliaryGanglion173.15
CingulateCortex322.8
Colorectaladenocarcinoma393.05
DorsalRootGanglion215.35
FetalThyroid227.65
Fetalbrain571.95
Fetalliver213.45
Fetallung464
GlobusPallidus200.1
Heart1349.75
Hypothalamus685.8
Kidney305.25
Leukemia_chronicMyelogenousK-562998.55
Leukemia_promyelocytic-HL-601072.65
Leukemialymphoblastic(MOLT-4)635.5
Liver352.95
Lung771.65
Lymphnode287.55
Lymphoma_burkitts(Daudi)1443.45
Lymphoma_burkitts(Raji)2361.65
MedullaOblongata310.95
OccipitalLobe429.65
OlfactoryBulb361.8
Ovary243.2
Pancreas406
PancreaticIslet591.9
ParietalLobe401
Pituitary395.7
Placenta592.6
Pons240.35
PrefrontalCortex497.5
Prostate696.2
Salivarygland491.3
SkeletalMuscle246.9
Skin251.05
SmoothMuscle750.1
Spinalcord398.2
SubthalamicNucleus326.65
SuperiorCervicalGanglion171.5
TemporalLobe268.3
Testis709.55
TestisGermCell535.5
TestisIntersitial580.2
TestisLeydigCell423.85
TestisSeminiferousTubule341.05
Thalamus562.15
Thymus370.2
Thyroid818.2
Tongue463.85
Tonsil375.35
Trachea272.95
TrigeminalGanglion177
Uterus388.5
UterusCorpus212.6
WholeBlood286.8
Wholebrain719.1
colon696.7
pineal_day1255.3
pineal_night1243.82
retina749.925
small_intestine541
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P75268
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.56 ± 0.25
Basal Forebrain10.75 ± 0.21
Basal Part of Pons11.24 ± 0.19
Cerebellar Cortex11.2 ± 0.23
Cerebellar Nuclei11.67 ± 0.2
Claustrum10.57 ± 0.44
Epithalamus10.83 ± 0.33
Frontal Lobe11.15 ± 0.34
Globus Pallidus10.72 ± 0.17
Hypothalamus11.23 ± 0.25
Insula11.11 ± 0.35
Limbic Lobe10.67 ± 0.53
Mesencephalon10.98 ± 0.44
Myelencephalon10.86 ± 0.44
Occipital Lobe10.47 ± 0.51
Parietal Lobe10.94 ± 0.41
Pontine Tegmentum10.94 ± 0.4
Striatum10.34 ± 0.37
Subthalamus11.62 ± 0.23
Temporal Lobe10.96 ± 0.33
Thalamus10.92 ± 0.28
White Matter10.35 ± 0.31
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Vdac2CBCerebellum48.46
61.94
Vdac2CTXCerebral cortex54.31
53.13
Vdac2HIPHippocampal region57.35
60.81
Vdac2HPFHippocampal formation59.04
59.22
Vdac2HYHypothalamus46.36
39.66
Vdac2LSXLateral septal complex33.23
21.25
Vdac2MBMidbrain46.08
46.62
Vdac2MYMedulla70.52
71.41
Vdac2OLFOlfactory bulb58.48
56.12
Vdac2PPons64.53
68.74
Vdac2PALPallidum43.15
47.64
Vdac2RHPRetrohippocampal region59.83
56.71
Vdac2sAMYStriatum-like amygdalar nuclei39.93
29.76
Vdac2STRStriatum28.56
20.64
Vdac2STRdStriatum dorsal region22.22
16.48
Vdac2STRvStriatum ventral region45.03
29.66
Vdac2THThalamus49.29
49.64
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00005376 13 123 135 LTFDTTFSPNTGK Peptide Atlas
VDAC2_HUMAN_0 0 0 0 LTFDTTFSPNTGK PRIDE
VDAC2_HUMAN_0 0 0 0 LTLSALVDGK PRIDE
VDAC2_HUMAN_0 0 0 0 YQLDPTASISAK PRIDE
VDAC2_HUMAN_108 13 108 120 LTFDTTFSPNTGK PRIDE
VDAC2_HUMAN_108 14 108 121 LTFDTTFSPNTGKK PRIDE
VDAC2_HUMAN_122 13 122 134 LTFDTTFSPNTGK PRIDE
VDAC2_HUMAN_122 14 122 135 LTFDTTFSPNTGKK PRIDE
VDAC2_HUMAN_178 8 178 185 NNFAVGYR PRIDE
VDAC2_HUMAN_186 23 186 208 TGDFQLHTNVNDGTEFGGSIYQK PRIDE
VDAC2_HUMAN_192 8 192 199 NNFAVGYR PRIDE
VDAC2_HUMAN_200 23 200 222 TGDFQLHTNVNDGTEFGGSIYQK PRIDE
VDAC2_HUMAN_230 6 230 235 FGIAAK PRIDE
VDAC2_HUMAN_236 12 236 247 YQLDPTASISAK PRIDE
VDAC2_HUMAN_248 20 248 267 VNNSSLIGVGYTQTLRPGVK PRIDE
VDAC2_HUMAN_250 12 250 261 YQLDPTASISAK PRIDE
VDAC2_HUMAN_251 12 251 262 YQLDPTASISAK PRIDE
VDAC2_HUMAN_262 20 262 281 VNNSSLIGVGYTQTLRPGVK PRIDE
VDAC2_HUMAN_268 10 268 277 LTLSALVDGK PRIDE
VDAC2_HUMAN_27 5 27 31 DIFNK PRIDE
VDAC2_HUMAN_282 10 282 291 LTLSALVDGK PRIDE
VDAC2_HUMAN_283 10 283 292 LTLSALVDGK PRIDE
VDAC2_HUMAN_32 8 32 39 GFGFGLVK PRIDE
VDAC2_HUMAN_46 19 46 64 SCSGVEFSTSGSSNTDTGK PRIDE
VDAC2_HUMAN_58 21 58 78 TKSCSGVEFSTSGSSNTDTGK PRIDE
VDAC2_HUMAN_60 19 60 78 SCSGVEFSTSGSSNTDTGK PRIDE
VDAC2_HUMAN_61 19 61 79 SCSGVEFSTSGSSNTDTGK PRIDE
VDAC2_HUMAN_65 8 65 72 VTGTLETK PRIDE
VDAC2_HUMAN_73 13 73 85 YKWCEYGLTFTEK PRIDE
VDAC2_HUMAN_75 11 75 85 WCEYGLTFTEK PRIDE
VDAC2_HUMAN_86 22 86 107 WNTDNTLGTEIAIEDQICQGLK PRIDE
VDAC2_HUMAN_87 13 87 99 YKWCEYGLTFTEK PRIDE
VDAC2_HUMAN_89 11 89 99 WCEYGLTFTEK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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