AutismKB 2.0

Annotation Detail for VEGFC


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Basic Information Top
Gene Symbol:VEGFC ( Flt4-L,VRP )
Gene Full Name: vascular endothelial growth factor C
Band: 4q34.3
Quick LinksEntrez ID:7424; OMIM: 601528; Uniprot ID:VEGFC_HUMAN; ENSEMBL ID: ENSG00000150630; HGNC ID: 12682
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus15 / 56401226
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult18 / 19391219
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal56 / 336030716
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone5 / 7165569
bone marrow2 / 4880140
brain5 / 11009894
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung10 / 33697429
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin15 / 21057471
spleen1 / 5395218
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus2 / 2328788
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209946_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.85
Adipocyte11.25
AdrenalCortex7.1
Adrenalgland9.95
Amygdala6.65
Appendix11.25
AtrioventricularNode4.8
BDCA4+_DentriticCells6.95
Bonemarrow6.55
BronchialEpithelialCells119.5
CD105+_Endothelial7.2
CD14+_Monocytes6.6
CD19+_BCells(neg._sel.)6.45
CD33+_Myeloid7.65
CD34+7.8
CD4+_Tcells6.5
CD56+_NKCells7.4
CD71+_EarlyErythroid5.7
CD8+_Tcells5.9
CardiacMyocytes13.3
Caudatenucleus5.5
Cerebellum5.2
CerebellumPeduncles7.3
CiliaryGanglion4.6
CingulateCortex6.6
Colorectaladenocarcinoma6.25
DorsalRootGanglion5.55
FetalThyroid17.05
Fetalbrain6.05
Fetalliver5.5
Fetallung9.2
GlobusPallidus4.7
Heart8.2
Hypothalamus6.9
Kidney5.35
Leukemia_chronicMyelogenousK-5625.8
Leukemia_promyelocytic-HL-605.65
Leukemialymphoblastic(MOLT-4)4.95
Liver11.25
Lung32.6
Lymphnode5.9
Lymphoma_burkitts(Daudi)8.15
Lymphoma_burkitts(Raji)9.2
MedullaOblongata6.45
OccipitalLobe5.7
OlfactoryBulb5.1
Ovary4.4
Pancreas5.15
PancreaticIslet6.9
ParietalLobe6.9
Pituitary7.45
Placenta6.75
Pons6.1
PrefrontalCortex7.9
Prostate7.45
Salivarygland5.3
SkeletalMuscle8
Skin5
SmoothMuscle106.8
Spinalcord6.65
SubthalamicNucleus6
SuperiorCervicalGanglion11.15
TemporalLobe5.9
Testis5.45
TestisGermCell5.25
TestisIntersitial5.4
TestisLeydigCell6.4
TestisSeminiferousTubule5.45
Thalamus6.55
Thymus4.8
Thyroid68.4
Tongue6.7
Tonsil6.2
Trachea5.4
TrigeminalGanglion6.65
Uterus13.65
UterusCorpus8.2
WholeBlood7.6
Wholebrain5.2
colon6.35
pineal_day7.34
pineal_night7.44
retina7.675
small_intestine6.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16849_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.88 ± 0.75
Basal Forebrain2.53 ± 0.28
Basal Part of Pons2.58 ± 0.77
Cerebellar Cortex2.5 ± 0.65
Cerebellar Nuclei3.21 ± 0.98
Claustrum3.21 ± 0.65
Epithalamus3.59 ± 0.49
Frontal Lobe2.63 ± 0.71
Globus Pallidus3.68 ± 0.63
Hypothalamus2.6 ± 0.64
Insula2.89 ± 0.66
Limbic Lobe2.59 ± 0.87
Mesencephalon2.83 ± 0.74
Myelencephalon2.83 ± 0.74
Occipital Lobe3.07 ± 0.61
Parietal Lobe2.76 ± 0.92
Pontine Tegmentum2.81 ± 0.73
Striatum3.22 ± 0.68
Subthalamus2.59 ± 0.51
Temporal Lobe2.63 ± 0.74
Thalamus3.29 ± 0.67
White Matter3.12 ± 0.37
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
VegfcCBCerebellum10.47
11.77
VegfcCTXCerebral cortex10.16
7.9
VegfcHIPHippocampal region7.67
7.84
VegfcHPFHippocampal formation8.12
7.51
VegfcHYHypothalamus1.93
1.83
VegfcLSXLateral septal complex0.83
0.49
VegfcMBMidbrain1.28
1.34
VegfcMYMedulla7.07
8.03
VegfcOLFOlfactory bulb18.16
14.1
VegfcPPons3.41
4.16
VegfcPALPallidum9.58
9.74
VegfcRHPRetrohippocampal region8.5
6.68
VegfcsAMYStriatum-like amygdalar nuclei16.67
12.6
VegfcSTRStriatum8.21
6.1
VegfcSTRdStriatum dorsal region7.3
5.51
VegfcSTRvStriatum ventral region8.31
5.65
VegfcTHThalamus9.41
9.41
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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