AutismKB 2.0

Annotation Detail for VIP


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Basic Information Top
Gene Symbol:VIP ( MGC13587,PHM27 )
Gene Full Name: vasoactive intestinal peptide
Band: 6q25.2
Quick LinksEntrez ID:7432; OMIM: 192320; Uniprot ID:VIP_HUMAN; ENSEMBL ID: ENSG00000146469; HGNC ID: 12693
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body10 / 70761141
blastocyst0 / 623190 
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile9 / 55556161
adult7 / 19391213
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal26 / 33603077
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain17 / 110098915
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine1 / 2344724
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve4 / 15768253
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis2 / 3304426
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206577_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.15
Adipocyte9.2
AdrenalCortex14.2
Adrenalgland9.1
Amygdala9.8
Appendix27.7
AtrioventricularNode12.8
BDCA4+_DentriticCells8.45
Bonemarrow12
BronchialEpithelialCells8.6
CD105+_Endothelial9.05
CD14+_Monocytes10.2
CD19+_BCells(neg._sel.)9.3
CD33+_Myeloid10.7
CD34+10.4
CD4+_Tcells8.95
CD56+_NKCells9.65
CD71+_EarlyErythroid9.1
CD8+_Tcells7.95
CardiacMyocytes17.95
Caudatenucleus8.6
Cerebellum7.85
CerebellumPeduncles13.3
CiliaryGanglion11.15
CingulateCortex10.65
Colorectaladenocarcinoma9.3
DorsalRootGanglion11.45
FetalThyroid10.4
Fetalbrain9.2
Fetalliver8.8
Fetallung6.75
GlobusPallidus8.85
Heart17.3
Hypothalamus10.05
Kidney9.7
Leukemia_chronicMyelogenousK-5628.35
Leukemia_promyelocytic-HL-608.3
Leukemialymphoblastic(MOLT-4)7
Liver16.55
Lung10.1
Lymphnode7.25
Lymphoma_burkitts(Daudi)12.95
Lymphoma_burkitts(Raji)16.6
MedullaOblongata8.25
OccipitalLobe8.6
OlfactoryBulb7.15
Ovary13.65
Pancreas8.45
PancreaticIslet10.6
ParietalLobe11.85
Pituitary11.05
Placenta8.8
Pons10.35
PrefrontalCortex10.25
Prostate10.25
Salivarygland9.3
SkeletalMuscle17.9
Skin12.15
SmoothMuscle10.55
Spinalcord9.75
SubthalamicNucleus10.3
SuperiorCervicalGanglion20.4
TemporalLobe10.4
Testis7.9
TestisGermCell6.95
TestisIntersitial8.7
TestisLeydigCell10.75
TestisSeminiferousTubule8.15
Thalamus10.1
Thymus6.65
Thyroid10.45
Tongue12.9
Tonsil9.75
Trachea7.65
TrigeminalGanglion15.65
Uterus7.05
UterusCorpus11.6
WholeBlood10
Wholebrain8.7
colon39.6
pineal_day11.94
pineal_night10.96
retina11.225
small_intestine28.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14716_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.97 ± 1.09
Basal Forebrain6.58 ± 0.41
Basal Part of Pons5.1 ± 0.42
Cerebellar Cortex5.16 ± 0.77
Cerebellar Nuclei4.84 ± 0.61
Claustrum6.54 ± 0.68
Epithalamus5.65 ± 1.43
Frontal Lobe6.43 ± 0.92
Globus Pallidus3.21 ± 2.22
Hypothalamus8.58 ± 1.29
Insula6.65 ± 0.4
Limbic Lobe6.89 ± 0.73
Mesencephalon6.19 ± 1.49
Myelencephalon6.11 ± 1.06
Occipital Lobe6.3 ± 0.9
Parietal Lobe6.81 ± 0.92
Pontine Tegmentum6.39 ± 1.3
Striatum4.9 ± 2.3
Subthalamus6.29 ± 0.99
Temporal Lobe6.76 ± 0.71
Thalamus4.73 ± 0.91
White Matter4.37 ± 1.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
VipCBCerebellum0.52
0.88
VipCTXCerebral cortex9.39
15.62
VipHIPHippocampal region3.1
6
VipHPFHippocampal formation4.74
8.27
VipHYHypothalamus0.82
0.96
VipLSXLateral septal complex2.62
4.58
VipMBMidbrain1.92
3.14
VipMYMedulla2.13
3.24
VipOLFOlfactory bulb11.65
15.03
VipPPons0.34
0.47
VipPALPallidum0.45
0.58
VipRHPRetrohippocampal region8.73
13.16
VipsAMYStriatum-like amygdalar nuclei0.98
1.33
VipSTRStriatum1.03
1.65
VipSTRdStriatum dorsal region0.86
1.4
VipSTRvStriatum ventral region0.81
1.17
VipTHThalamus0.3
0.38
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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