Annotation Detail for VTN
Basic Information Top
| Gene Symbol: | VTN ( V75,VN,VNT ) |
|---|---|
| Gene Full Name: | vitronectin |
| Band: | 17q11.2 |
| Quick Links | Entrez ID:7448; OMIM: 193190; Uniprot ID:VTNC_HUMAN; ENSEMBL ID: ENSG00000109072; HGNC ID: 12724 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.2257
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 1 / 62319 | 16 | |
| fetus | 160 / 564012 | 283 |  |
| neonate | 1 / 31097 | 32 | |
| infant | 1 / 23620 | 42 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 129 / 1939121 | 66 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 2 / 12794 | 156 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 1 / 94178 | 10 |  |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 1 / 82823 | 12 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 5 / 263845 | 18 | |
| glioma | 1 / 106883 | 9 | |
| head and neck tumor | 2 / 136302 | 14 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 17 / 95842 | 177 | |
| liver tumor | 39 / 96359 | 404 | |
| lung tumor | 8 / 103127 | 77 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 371 / 3360307 | 110 | |
| ovarian tumor | 2 / 76682 | 26 | |
| pancreatic tumor | 2 / 104616 | 19 | |
| primitive neuroectodermal tumor of the CNS | 1 / 125680 | 7 | |
| prostate cancer | 1 / 102680 | 9 | |
| retinoblastoma | 2 / 46356 | 43 | |
| skin tumor | 1 / 124949 | 8 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 1 / 90257 | 11 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 6 / 33197 | 180 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 17 / 123478 | 137 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 11 / 1100989 | 9 | |
| cervix | 4 / 48171 | 83 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 3 / 215722 | 13 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 8 / 211054 | 37 | |
| heart | 12 / 89626 | 133 | |
| intestine | 0 / 234472 | 0 | |
| kidney | 2 / 211777 | 9 | |
| larynx | 1 / 24145 | 41 | |
| liver | 239 / 207743 | 1150 |  |
| lung | 21 / 336974 | 62 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 31 / 153271 | 202 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 2 / 102051 | 19 | |
| pancreas | 3 / 214812 | 13 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 24 / 280825 | 85 | |
| prostate | 1 / 189345 | 5 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 1 / 210574 | 4 | |
| spleen | 5 / 53952 | 92 | |
| stomach | 1 / 96619 | 10 | |
| testis | 1 / 330442 | 3 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 1 / 13680 | 73 | |
| uterus | 1 / 232878 | 4 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 204534_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 5.6 | |
| Adipocyte | 4.65 | |
| AdrenalCortex | 37.8 | |
| Adrenalgland | 37.75 | |
| Amygdala | 4.75 | |
| Appendix | 4.8 | |
| AtrioventricularNode | 3.85 | |
| BDCA4+_DentriticCells | 4.9 | |
| Bonemarrow | 4.95 | |
| BronchialEpithelialCells | 4.55 | |
| CD105+_Endothelial | 4.7 | |
| CD14+_Monocytes | 5.25 | |
| CD19+_BCells(neg._sel.) | 5.2 | |
| CD33+_Myeloid | 5.95 | |
| CD34+ | 5.9 | |
| CD4+_Tcells | 5.1 | |
| CD56+_NKCells | 5.6 | |
| CD71+_EarlyErythroid | 4.35 | |
| CD8+_Tcells | 4.3 | |
| CardiacMyocytes | 5.9 | |
| Caudatenucleus | 4.2 | |
| Cerebellum | 3.8 | |
| CerebellumPeduncles | 5.45 | |
| CiliaryGanglion | 3.4 | |
| CingulateCortex | 4.8 | |
| Colorectaladenocarcinoma | 4.7 | |
| DorsalRootGanglion | 3.7 | |
| FetalThyroid | 4.6 | |
| Fetalbrain | 4.65 | |
| Fetalliver | 3061.7 | |
| Fetallung | 894.5 | |
| GlobusPallidus | 3.45 | |
| Heart | 43.2 | |
| Hypothalamus | 5.05 | |
| Kidney | 4.05 | |
| Leukemia_chronicMyelogenousK-562 | 4.2 | |
| Leukemia_promyelocytic-HL-60 | 4.15 | |
| Leukemialymphoblastic(MOLT-4) | 3.7 | |
| Liver | 17346.1 | |
| Lung | 5.2 | |
| Lymphnode | 4.05 | |
| Lymphoma_burkitts(Daudi) | 5.95 | |
| Lymphoma_burkitts(Raji) | 6.5 | |
| MedullaOblongata | 4.3 | |
| OccipitalLobe | 4.2 | |
| OlfactoryBulb | 3.7 | |
| Ovary | 3.2 | |
| Pancreas | 3.8 | |
| PancreaticIslet | 5 | |
| ParietalLobe | 4.9 | |
| Pituitary | 5.45 | |
| Placenta | 7.4 | |
| Pons | 4.45 | |
| PrefrontalCortex | 5.8 | |
| Prostate | 7.15 | |
| Salivarygland | 3.85 | |
| SkeletalMuscle | 5.65 | |
| Skin | 3.6 | |
| SmoothMuscle | 5.2 | |
| Spinalcord | 4.95 | |
| SubthalamicNucleus | 4.3 | |
| SuperiorCervicalGanglion | 5.3 | |
| TemporalLobe | 4.35 | |
| Testis | 4.05 | |
| TestisGermCell | 3.95 | |
| TestisIntersitial | 3.9 | |
| TestisLeydigCell | 4.7 | |
| TestisSeminiferousTubule | 4.05 | |
| Thalamus | 4.75 | |
| Thymus | 3.65 | |
| Thyroid | 5.75 | |
| Tongue | 4.65 | |
| Tonsil | 4.6 | |
| Trachea | 4 | |
| TrigeminalGanglion | 4.85 | |
| Uterus | 3.75 | |
| UterusCorpus | 4.3 | |
| WholeBlood | 5.1 | |
| Wholebrain | 3.8 | |
| colon | 4.75 | |
| pineal_day | 10.12 | |
| pineal_night | 12.92 | |
| retina | 5.725 | |
| small_intestine | 4.5 | |
- Probe name: A_32_P216193
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 1.96 ± 0.9 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 1.62 ± 0.27 | |
| Basal Part of Pons | 1.23 ± 0.37 | |
| Cerebellar Cortex | 1.62 ± 0.82 | |
| Cerebellar Nuclei | 1.92 ± 0.71 | |
| Claustrum | 2.44 ± 0.97 | |
| Epithalamus | 1.55 ± 0.72 | |
| Frontal Lobe | 1.53 ± 0.76 | |
| Globus Pallidus | 2.13 ± 0.64 | |
| Hypothalamus | 1.5 ± 0.72 | |
| Insula | 1.28 ± 0.48 | |
| Limbic Lobe | 1.66 ± 0.82 | |
| Mesencephalon | 1.77 ± 0.66 | |
| Myelencephalon | 1.68 ± 0.72 | |
| Occipital Lobe | 1.8 ± 0.87 | |
| Parietal Lobe | 1.55 ± 0.75 | |
| Pontine Tegmentum | 1.65 ± 0.74 | |
| Striatum | 1.85 ± 0.67 | |
| Subthalamus | 1.66 ± 0.57 | |
| Temporal Lobe | 1.52 ± 0.67 | |
| Thalamus | 1.59 ± 0.83 | |
| White Matter | 2.02 ± 0.42 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Vtn | CB | Cerebellum | 42.08 | |
| 80.52 | | |||
| Vtn | CTX | Cerebral cortex | 42.98 | |
| 56.45 | | |||
| Vtn | HIP | Hippocampal region | 29.48 | |
| 60.36 | | |||
| Vtn | HPF | Hippocampal formation | 31.66 | |
| 58.7 | | |||
| Vtn | HY | Hypothalamus | 26.58 | |
| 44.23 | | |||
| Vtn | LSX | Lateral septal complex | 27.09 | |
| 44.71 | | |||
| Vtn | MB | Midbrain | 38.04 | |
| 65.88 | | |||
| Vtn | MY | Medulla | 37.38 | |
| 63.36 | | |||
| Vtn | OLF | Olfactory bulb | 45.39 | |
| 68.39 | | |||
| Vtn | P | Pons | 36.26 | |
| 58.42 | | |||
| Vtn | PAL | Pallidum | 26.38 | |
| 45.42 | | |||
| Vtn | RHP | Retrohippocampal region | 34.07 | |
| 54.23 | | |||
| Vtn | sAMY | Striatum-like amygdalar nuclei | 28.44 | |
| 49.77 | | |||
| Vtn | STR | Striatum | 29.89 | |
| 45.33 | | |||
| Vtn | STRd | Striatum dorsal region | 29.55 | |
| 45.5 | | |||
| Vtn | STRv | Striatum ventral region | 32.39 | |
| 42.43 | | |||
| Vtn | TH | Thalamus | 37.53 | |
| 61.14 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00024282 | 21 | 87 | 107 | ATVHEQVGGPSLTSDLQAQSK | Peptide Atlas |