AutismKB 2.0

Annotation Detail for WIPF1


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Basic Information Top
Gene Symbol:WIPF1 ( MGC111041,PRPL-2,WASPIP,WIP )
Gene Full Name: WAS/WASL interacting protein family, member 1
Band: 2q31.1
Quick LinksEntrez ID:7456; OMIM: 602357; Uniprot ID:WIPF1_HUMAN; ENSEMBL ID: ENSG00000115935; HGNC ID: 12736
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst1 / 6231916
fetus24 / 56401242
neonate1 / 3109732
infant0 / 236200 
juvenile2 / 5555635
adult104 / 193912153
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor13 / 26384549
glioma4 / 10688337
head and neck tumor5 / 13630236
kidney tumor1 / 6895914
leukemia18 / 95842187
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma20 / 71755278
non-neoplasia7 / 9725071
normal183 / 336030754
ovarian tumor8 / 76682104
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor20 / 124949160
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor11 / 90257121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood25 / 123478202
bone1 / 7165513
bone marrow4 / 4880181
brain17 / 110098915
cervix0 / 481710 
connective tissue5 / 14925533
ear3 / 16212185
embryonic tissue7 / 21572232
esophagus1 / 2020949
eye4 / 21105418
heart3 / 8962633
intestine1 / 2344724
kidney4 / 21177718
larynx2 / 2414582
liver1 / 2077434
lung11 / 33697432
lymph12 / 44270271
lymph node53 / 91610578
mammary gland6 / 15327139
mouth0 / 670520 
muscle3 / 10771527
nerve1 / 1576863
ovary8 / 10205178
pancreas9 / 21481241
parathyroid1 / 2053948
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta9 / 28082532
prostate8 / 18934542
salivary gland0 / 201550 
skin24 / 210574113
spleen3 / 5395255
stomach1 / 9661910
testis1 / 3304423
thymus4 / 8113149
thyroid3 / 4747363
tonsil5 / 16999294
trachea2 / 5241338
umbilical cord0 / 136800 
uterus14 / 23287860
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202663_at
Cell line Expression level Expression bar
721_B_lymphoblasts173.85
Adipocyte13
AdrenalCortex25.85
Adrenalgland13.15
Amygdala12.15
Appendix36.3
AtrioventricularNode21.25
BDCA4+_DentriticCells106.7
Bonemarrow31.65
BronchialEpithelialCells13.4
CD105+_Endothelial14
CD14+_Monocytes163.3
CD19+_BCells(neg._sel.)95.85
CD33+_Myeloid157.25
CD34+65.7
CD4+_Tcells364.1
CD56+_NKCells456.4
CD71+_EarlyErythroid14.45
CD8+_Tcells305.35
CardiacMyocytes35.2
Caudatenucleus12.7
Cerebellum11.15
CerebellumPeduncles20.55
CiliaryGanglion20.95
CingulateCortex16.7
Colorectaladenocarcinoma12.85
DorsalRootGanglion21.4
FetalThyroid20.1
Fetalbrain12.1
Fetalliver12.15
Fetallung8.7
GlobusPallidus13.35
Heart31.5
Hypothalamus14.95
Kidney14.95
Leukemia_chronicMyelogenousK-56212.05
Leukemia_promyelocytic-HL-6023.8
Leukemialymphoblastic(MOLT-4)13.5
Liver25.5
Lung15.8
Lymphnode60
Lymphoma_burkitts(Daudi)45.3
Lymphoma_burkitts(Raji)60.45
MedullaOblongata11.1
OccipitalLobe12.85
OlfactoryBulb17.3
Ovary14.95
Pancreas13.7
PancreaticIslet15.85
ParietalLobe24.75
Pituitary16
Placenta14.05
Pons15.45
PrefrontalCortex15.6
Prostate16.9
Salivarygland35.8
SkeletalMuscle41.1
Skin23.6
SmoothMuscle17.65
Spinalcord16.1
SubthalamicNucleus16.05
SuperiorCervicalGanglion33.55
TemporalLobe18.1
Testis10.7
TestisGermCell9.6
TestisIntersitial12.8
TestisLeydigCell16.35
TestisSeminiferousTubule11.5
Thalamus23.45
Thymus10.75
Thyroid14.65
Tongue22
Tonsil35.9
Trachea11.5
TrigeminalGanglion33.9
Uterus12.05
UterusCorpus20.15
WholeBlood289.55
Wholebrain9.8
colon17.4
pineal_day15.56
pineal_night16.16
retina21.425
small_intestine22.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P330611
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.3 ± 0.78
Basal Forebrain6.59 ± 0.47
Basal Part of Pons6.43 ± 0.78
Cerebellar Cortex5.54 ± 0.4
Cerebellar Nuclei7.68 ± 0.56
Claustrum5.56 ± 0.72
Epithalamus6.17 ± 0.88
Frontal Lobe6.14 ± 0.89
Globus Pallidus8.38 ± 0.44
Hypothalamus6 ± 0.76
Insula5.58 ± 0.42
Limbic Lobe5.72 ± 0.89
Mesencephalon6.35 ± 0.92
Myelencephalon6.3 ± 0.7
Occipital Lobe6.16 ± 0.84
Parietal Lobe6.01 ± 0.85
Pontine Tegmentum6.33 ± 0.59
Striatum7.02 ± 0.64
Subthalamus7.02 ± 0.32
Temporal Lobe5.92 ± 0.69
Thalamus6.64 ± 0.53
White Matter9.32 ± 0.4
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
WaspipCBCerebellum14.2
20.87
WaspipCTXCerebral cortex17.2
12.94
WaspipHIPHippocampal region18.36
17.91
WaspipHPFHippocampal formation20.42
18.67
WaspipHYHypothalamus7.31
8.14
WaspipLSXLateral septal complex2.86
2.32
WaspipMBMidbrain2.9
3.44
WaspipMYMedulla7.24
9.83
WaspipOLFOlfactory bulb20.38
16.92
WaspipPPons5.66
9.7
WaspipPALPallidum7.92
7.65
WaspipRHPRetrohippocampal region24.34
19.66
WaspipsAMYStriatum-like amygdalar nuclei15.61
11.89
WaspipSTRStriatum13.16
10.23
WaspipSTRdStriatum dorsal region16.73
13.08
WaspipSTRvStriatum ventral region7.06
5.91
WaspipTHThalamus5.43
4.81
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00077416 27 412 438 SGPRPPLPPDRPSAGAPPPPPPSTSIR Peptide Atlas
WIPF1_HUMAN_159 8 159 166 SGPPEPQR PRIDE
WIPF1_HUMAN_258 21 258 278 ALDDKPPPPPPPVGNRPSIHR PRIDE
WIPF1_HUMAN_353 22 353 374 SGPLPPPPSERPPPPVRDPPGR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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