AutismKB 2.0

Annotation Detail for CLIP2


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Basic Information Top
Gene Symbol:CLIP2 ( CLIP,CLIP-115,CYLN2,KIAA0291,MGC11333,WBSCR3,WBSCR4,WSCR3,WSCR4 )
Gene Full Name: CAP-GLY domain containing linker protein 2
Band: 7q11.23
Quick LinksEntrez ID:7461; OMIM: 603432; Uniprot ID:CLIP2_HUMAN; ENSEMBL ID: ENSG00000106665; HGNC ID: 2586
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst2 / 6231932
fetus21 / 56401237
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult66 / 193912134
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma8 / 8282396
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor15 / 26384556
glioma17 / 106883159
head and neck tumor3 / 13630222
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma3 / 7175541
non-neoplasia8 / 9725082
normal95 / 336030728
ovarian tumor6 / 7668278
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites5 / 40015124
bladder0 / 297570 
blood0 / 1234780 
bone8 / 71655111
bone marrow0 / 488010 
brain65 / 110098959
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye13 / 21105461
heart2 / 8962622
intestine10 / 23447242
kidney4 / 21177718
larynx0 / 241450 
liver4 / 20774319
lung10 / 33697429
lymph3 / 4427067
lymph node4 / 9161043
mammary gland1 / 1532716
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary7 / 10205168
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland3 / 20155148
skin1 / 2105744
spleen0 / 539520 
stomach2 / 9661920
testis4 / 33044212
thymus2 / 8113124
thyroid1 / 4747321
tonsil1 / 1699958
trachea1 / 5241319
umbilical cord2 / 13680146
uterus2 / 2328788
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211031_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts66.55
Adipocyte4.55
AdrenalCortex4.8
Adrenalgland3.85
Amygdala62.6
Appendix3.95
AtrioventricularNode3.35
BDCA4+_DentriticCells5.35
Bonemarrow4.15
BronchialEpithelialCells4.35
CD105+_Endothelial4.7
CD14+_Monocytes13.65
CD19+_BCells(neg._sel.)15.65
CD33+_Myeloid11.25
CD34+24.05
CD4+_Tcells4.55
CD56+_NKCells8
CD71+_EarlyErythroid3.95
CD8+_Tcells3.95
CardiacMyocytes5.8
Caudatenucleus26.7
Cerebellum6.05
CerebellumPeduncles29.8
CiliaryGanglion3.45
CingulateCortex84.5
Colorectaladenocarcinoma75.5
DorsalRootGanglion3.65
FetalThyroid3.95
Fetalbrain126.9
Fetalliver3.7
Fetallung3.7
GlobusPallidus29.6
Heart5.5
Hypothalamus43.05
Kidney3.55
Leukemia_chronicMyelogenousK-5626.25
Leukemia_promyelocytic-HL-603.75
Leukemialymphoblastic(MOLT-4)3.5
Liver5.85
Lung5.2
Lymphnode3.9
Lymphoma_burkitts(Daudi)5.8
Lymphoma_burkitts(Raji)58.2
MedullaOblongata41.4
OccipitalLobe34.15
OlfactoryBulb38.55
Ovary2.95
Pancreas3.7
PancreaticIslet4.7
ParietalLobe39.1
Pituitary5.2
Placenta8.9
Pons48.1
PrefrontalCortex196.75
Prostate5.85
Salivarygland3.5
SkeletalMuscle5.2
Skin3.45
SmoothMuscle11.6
Spinalcord92.1
SubthalamicNucleus32.1
SuperiorCervicalGanglion5
TemporalLobe48.7
Testis3.6
TestisGermCell3.6
TestisIntersitial3.5
TestisLeydigCell4.3
TestisSeminiferousTubule3.6
Thalamus70.85
Thymus3.65
Thyroid5.45
Tongue4.5
Tonsil4.45
Trachea3.55
TrigeminalGanglion4.35
Uterus3.8
UterusCorpus10.7
WholeBlood5.05
Wholebrain86.2
colon4.65
pineal_day10.5
pineal_night8
retina31.25
small_intestine4.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7081_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.17 ± 0.46
Basal Forebrain7.01 ± 0.46
Basal Part of Pons7 ± 0.42
Cerebellar Cortex6.63 ± 0.22
Cerebellar Nuclei6.96 ± 0.33
Claustrum7.67 ± 0.47
Epithalamus6.69 ± 0.28
Frontal Lobe6.74 ± 0.43
Globus Pallidus7.68 ± 0.28
Hypothalamus6.63 ± 0.31
Insula6.66 ± 0.39
Limbic Lobe7.01 ± 0.55
Mesencephalon6.94 ± 0.47
Myelencephalon6.93 ± 0.54
Occipital Lobe7.21 ± 0.54
Parietal Lobe6.89 ± 0.44
Pontine Tegmentum6.82 ± 0.38
Striatum6.74 ± 0.49
Subthalamus6.67 ± 0.36
Temporal Lobe6.79 ± 0.41
Thalamus6.78 ± 0.4
White Matter8.16 ± 0.54
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cyln2CBCerebellum61.34
52.46
Cyln2CTXCerebral cortex100
94.77
Cyln2HIPHippocampal region91.36
100
Cyln2HPFHippocampal formation92.89
99.45
Cyln2HYHypothalamus72.91
72.06
Cyln2LSXLateral septal complex66.66
57.01
Cyln2MBMidbrain69.92
55.86
Cyln2MYMedulla63.99
50.53
Cyln2OLFOlfactory bulb92.91
98.38
Cyln2PPons62.83
47.04
Cyln2PALPallidum79.21
71.5
Cyln2RHPRetrohippocampal region94.16
96.81
Cyln2sAMYStriatum-like amygdalar nuclei82.62
82.41
Cyln2STRStriatum73.83
67.96
Cyln2STRdStriatum dorsal region72.56
63.09
Cyln2STRvStriatum ventral region71.65
71.84
Cyln2THThalamus84.77
75.2
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000737 16 385 400 ATSHICEVEKEIALLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018