AutismKB 2.0

Annotation Detail for WNT5A


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Basic Information Top
Gene Symbol:WNT5A ( hWNT5A )
Gene Full Name: wingless-type MMTV integration site family, member 5A
Band: 3p14.3
Quick LinksEntrez ID:7474; OMIM: 164975; Uniprot ID:WNT5A_HUMAN; ENSEMBL ID: ENSG00000114251; HGNC ID: 12784
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body10 / 70761141
blastocyst0 / 623190 
fetus15 / 56401226
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult46 / 193912123
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma3 / 17475171
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor2 / 2638457
glioma8 / 10688374
head and neck tumor4 / 13630229
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal90 / 336030726
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder3 / 29757100
blood0 / 1234780 
bone6 / 7165583
bone marrow1 / 4880120
brain19 / 110098917
cervix0 / 481710 
connective tissue3 / 14925520
ear2 / 16212123
embryonic tissue14 / 21572264
esophagus0 / 202090 
eye6 / 21105428
heart1 / 8962611
intestine2 / 2344728
kidney3 / 21177714
larynx0 / 241450 
liver0 / 2077430 
lung13 / 33697438
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth3 / 6705244
muscle3 / 10771527
nerve2 / 15768126
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta18 / 28082564
prostate3 / 18934515
salivary gland0 / 201550 
skin9 / 21057442
spleen0 / 539520 
stomach0 / 966190 
testis2 / 3304426
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus13 / 23287855
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205990_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.75
Adipocyte5.1
AdrenalCortex5.75
Adrenalgland4.45
Amygdala5.3
Appendix6.9
AtrioventricularNode5.85
BDCA4+_DentriticCells5.1
Bonemarrow5.3
BronchialEpithelialCells5
CD105+_Endothelial4.95
CD14+_Monocytes5.3
CD19+_BCells(neg._sel.)5.15
CD33+_Myeloid6.55
CD34+6.3
CD4+_Tcells5
CD56+_NKCells6.05
CD71+_EarlyErythroid4.85
CD8+_Tcells4.6
CardiacMyocytes6.95
Caudatenucleus4.55
Cerebellum4.2
CerebellumPeduncles5.9
CiliaryGanglion4.7
CingulateCortex5.3
Colorectaladenocarcinoma16.3
DorsalRootGanglion5.2
FetalThyroid5
Fetalbrain5.1
Fetalliver4.5
Fetallung4.3
GlobusPallidus3.95
Heart6.75
Hypothalamus5.5
Kidney4.35
Leukemia_chronicMyelogenousK-5624.55
Leukemia_promyelocytic-HL-6018.05
Leukemialymphoblastic(MOLT-4)4.05
Liver6.95
Lung5.5
Lymphnode4.35
Lymphoma_burkitts(Daudi)6.8
Lymphoma_burkitts(Raji)8
MedullaOblongata4.65
OccipitalLobe4.55
OlfactoryBulb4.05
Ovary3.95
Pancreas4.15
PancreaticIslet5.35
ParietalLobe5.55
Pituitary5.95
Placenta48.65
Pons4.95
PrefrontalCortex6.25
Prostate6.05
Salivarygland4.3
SkeletalMuscle6.4
Skin4.85
SmoothMuscle5.9
Spinalcord5.45
SubthalamicNucleus4.8
SuperiorCervicalGanglion6.8
TemporalLobe4.75
Testis4.4
TestisGermCell4.2
TestisIntersitial4.3
TestisLeydigCell5.1
TestisSeminiferousTubule4.4
Thalamus5.25
Thymus4.05
Thyroid6.4
Tongue6.25
Tonsil5.05
Trachea4.35
TrigeminalGanglion6.75
Uterus30.2
UterusCorpus5.4
WholeBlood5.45
Wholebrain4.35
colon5.2
pineal_day6.34
pineal_night6.32
retina6.275
small_intestine7.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P211926
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.9 ± 0.42
Basal Forebrain3.99 ± 0.58
Basal Part of Pons4.17 ± 0.53
Cerebellar Cortex5.03 ± 0.61
Cerebellar Nuclei5.12 ± 0.73
Claustrum4.88 ± 0.53
Epithalamus5.17 ± 0.35
Frontal Lobe5.05 ± 0.42
Globus Pallidus4.08 ± 0.71
Hypothalamus4.97 ± 0.96
Insula4.94 ± 0.39
Limbic Lobe5.03 ± 0.65
Mesencephalon4.96 ± 0.7
Myelencephalon4.79 ± 0.76
Occipital Lobe4.27 ± 0.64
Parietal Lobe4.98 ± 0.54
Pontine Tegmentum4.81 ± 0.58
Striatum3.62 ± 0.71
Subthalamus4.45 ± 0.71
Temporal Lobe4.91 ± 0.42
Thalamus4.86 ± 0.7
White Matter3.15 ± 0.31
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Wnt5aCBCerebellum100
84.36
Wnt5aCTXCerebral cortex84.7
59.36
Wnt5aHIPHippocampal region78.03
47.37
Wnt5aHPFHippocampal formation82.91
59.3
Wnt5aHYHypothalamus68.4
57.9
Wnt5aLSXLateral septal complex59.58
32.58
Wnt5aMBMidbrain70.65
44.98
Wnt5aMYMedulla77.74
71.72
Wnt5aOLFOlfactory bulb92.92
69.46
Wnt5aPPons68.02
60.14
Wnt5aPALPallidum66.03
50.14
Wnt5aRHPRetrohippocampal region82.78
65.81
Wnt5asAMYStriatum-like amygdalar nuclei74.6
49.05
Wnt5aSTRStriatum64.46
36.5
Wnt5aSTRdStriatum dorsal region58.53
31.4
Wnt5aSTRvStriatum ventral region76.06
52.22
Wnt5aTHThalamus79.15
66.18
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
WNT5A_HUMAN_201 12 201 212 ILMNLHNNEAGR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018