AutismKB 2.0

Annotation Detail for WNT6


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Basic Information Top
Gene Symbol:WNT6 ( - )
Gene Full Name: wingless-type MMTV integration site family, member 6
Band: 2q35
Quick LinksEntrez ID:7475; OMIM: 604663; Uniprot ID:WNT6_HUMAN; ENSEMBL ID: ENSG00000115596; HGNC ID: 12785
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus19 / 56401233
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult10 / 19391215
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal41 / 336030712
ovarian tumor4 / 7668252
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain3 / 11009892
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye3 / 21105414
heart6 / 8962666
intestine0 / 2344720 
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary5 / 10205148
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta8 / 28082528
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach2 / 9661920
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221609_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts12.5
Adipocyte10.3
AdrenalCortex15.8
Adrenalgland8.9
Amygdala10.55
Appendix11.1
AtrioventricularNode10.35
BDCA4+_DentriticCells11
Bonemarrow10.4
BronchialEpithelialCells9.7
CD105+_Endothelial10.55
CD14+_Monocytes10.95
CD19+_BCells(neg._sel.)10.35
CD33+_Myeloid13.05
CD34+12.25
CD4+_Tcells10.75
CD56+_NKCells11.65
CD71+_EarlyErythroid9.75
CD8+_Tcells8.65
CardiacMyocytes13.7
Caudatenucleus12.15
Cerebellum8.5
CerebellumPeduncles14.65
CiliaryGanglion7.9
CingulateCortex11.6
Colorectaladenocarcinoma60.75
DorsalRootGanglion8.85
FetalThyroid10.1
Fetalbrain10.45
Fetalliver8.95
Fetallung8.4
GlobusPallidus8.7
Heart14.2
Hypothalamus11.1
Kidney8.7
Leukemia_chronicMyelogenousK-5628.95
Leukemia_promyelocytic-HL-609
Leukemialymphoblastic(MOLT-4)8.4
Liver14.05
Lung11.2
Lymphnode9
Lymphoma_burkitts(Daudi)13.4
Lymphoma_burkitts(Raji)14.85
MedullaOblongata9.45
OccipitalLobe9.3
OlfactoryBulb15.1
Ovary7
Pancreas8.6
PancreaticIslet11.2
ParietalLobe11.7
Pituitary12.2
Placenta10.85
Pons10.55
PrefrontalCortex12.7
Prostate12
Salivarygland8.3
SkeletalMuscle18.2
Skin8.45
SmoothMuscle11.75
Spinalcord11.8
SubthalamicNucleus12.8
SuperiorCervicalGanglion13.4
TemporalLobe10.1
Testis9.9
TestisGermCell8.65
TestisIntersitial9.95
TestisLeydigCell10.35
TestisSeminiferousTubule10.3
Thalamus10.6
Thymus8
Thyroid13
Tongue10.85
Tonsil10.45
Trachea8.7
TrigeminalGanglion11.15
Uterus7.8
UterusCorpus9.5
WholeBlood11.25
Wholebrain8.7
colon9.3
pineal_day11.78
pineal_night11.96
retina12.6
small_intestine9.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P208513
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala13.2 ± 0.47
Basal Forebrain13.01 ± 0.38
Basal Part of Pons13.75 ± 0.35
Cerebellar Cortex13.12 ± 0.38
Cerebellar Nuclei13.37 ± 0.5
Claustrum13.09 ± 0.54
Epithalamus13.24 ± 0.33
Frontal Lobe13.53 ± 0.48
Globus Pallidus13.91 ± 0.3
Hypothalamus13.13 ± 0.8
Insula13.48 ± 0.57
Limbic Lobe13.58 ± 0.43
Mesencephalon13.2 ± 0.35
Myelencephalon13.43 ± 0.5
Occipital Lobe13.26 ± 0.47
Parietal Lobe13.35 ± 0.45
Pontine Tegmentum13.28 ± 0.54
Striatum13.61 ± 0.46
Subthalamus12.98 ± 0.36
Temporal Lobe13.44 ± 0.47
Thalamus13.39 ± 0.49
White Matter14.06 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Wnt6CBCerebellum12.19
13.9
Wnt6CTXCerebral cortex1.9
1.29
Wnt6HIPHippocampal region3.68
1.95
Wnt6HPFHippocampal formation2.71
1.55
Wnt6HYHypothalamus1.05
1.43
Wnt6LSXLateral septal complex0.67
1.02
Wnt6MBMidbrain1.99
1.7
Wnt6MYMedulla3.7
3.02
Wnt6OLFOlfactory bulb8.03
5.09
Wnt6PPons3.22
3.06
Wnt6PALPallidum0.68
0.86
Wnt6RHPRetrohippocampal region1.25
1.08
Wnt6sAMYStriatum-like amygdalar nuclei0.46
0.77
Wnt6STRStriatum0.44
0.39
Wnt6STRdStriatum dorsal region0.29
0.19
Wnt6STRvStriatum ventral region0.82
0.6
Wnt6THThalamus1.97
1.17
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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