AutismKB 2.0

Annotation Detail for WNT7B


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Basic Information Top
Gene Symbol:WNT7B ( - )
Gene Full Name: wingless-type MMTV integration site family, member 7B
Band: 22q13.31
Quick LinksEntrez ID:7477; OMIM: 601967; Uniprot ID:WNT7B_HUMAN; ENSEMBL ID: ENSG00000188064; HGNC ID: 12787
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult284 / 1939121146
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma5 / 10688346
head and neck tumor8 / 13630258
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal35 / 336030710
ovarian tumor1 / 7668213
pancreatic tumor14 / 104616133
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer16 / 102680155
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder2 / 2975767
blood0 / 1234780 
bone3 / 7165541
bone marrow0 / 488010 
brain12 / 110098910
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye14 / 21105466
heart1 / 8962611
intestine0 / 2344720 
kidney2 / 2117779
larynx0 / 241450 
liver1 / 2077434
lung10 / 33697429
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas14 / 21481265
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate16 / 18934584
salivary gland6 / 20155297
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217681_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.35
Adipocyte5.8
AdrenalCortex6.95
Adrenalgland5.7
Amygdala6.25
Appendix6.7
AtrioventricularNode4.45
BDCA4+_DentriticCells5
Bonemarrow5.75
BronchialEpithelialCells5.8
CD105+_Endothelial5.5
CD14+_Monocytes6.15
CD19+_BCells(neg._sel.)6
CD33+_Myeloid7.3
CD34+6.45
CD4+_Tcells5.8
CD56+_NKCells7.05
CD71+_EarlyErythroid5.45
CD8+_Tcells5.7
CardiacMyocytes7.65
Caudatenucleus5.25
Cerebellum4.75
CerebellumPeduncles6.65
CiliaryGanglion4.55
CingulateCortex6.45
Colorectaladenocarcinoma5.85
DorsalRootGanglion4.5
FetalThyroid5.7
Fetalbrain5.9
Fetalliver5.05
Fetallung4.85
GlobusPallidus4.35
Heart7.5
Hypothalamus6.4
Kidney4.85
Leukemia_chronicMyelogenousK-5625.3
Leukemia_promyelocytic-HL-605.15
Leukemialymphoblastic(MOLT-4)4.7
Liver8.15
Lung6.5
Lymphnode5.05
Lymphoma_burkitts(Daudi)7.45
Lymphoma_burkitts(Raji)8.25
MedullaOblongata5.4
OccipitalLobe6.15
OlfactoryBulb4.65
Ovary3.95
Pancreas4.7
PancreaticIslet6.3
ParietalLobe6.7
Pituitary6.9
Placenta6.1
Pons5.8
PrefrontalCortex7.4
Prostate6.95
Salivarygland4.7
SkeletalMuscle11.05
Skin6.4
SmoothMuscle6.7
Spinalcord6.3
SubthalamicNucleus5.35
SuperiorCervicalGanglion7.75
TemporalLobe5.35
Testis5.05
TestisGermCell4.95
TestisIntersitial4.9
TestisLeydigCell6.05
TestisSeminiferousTubule5.05
Thalamus6.1
Thymus4.15
Thyroid7
Tongue6.3
Tonsil5.75
Trachea4.95
TrigeminalGanglion5.85
Uterus4.85
UterusCorpus5.3
WholeBlood6.4
Wholebrain5.05
colon5.9
pineal_day6.64
pineal_night6.06
retina7.1
small_intestine5.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P911607
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala1.92 ± 0.97
Basal Forebrain1.46 ± 0.19
Basal Part of Pons1.18 ± 0.3
Cerebellar Cortex1.31 ± 0.67
Cerebellar Nuclei1.75 ± 0.71
Claustrum2.33 ± 0.81
Epithalamus1.23 ± 0.71
Frontal Lobe1.33 ± 0.61
Globus Pallidus2.08 ± 0.33
Hypothalamus1.57 ± 0.69
Insula1.36 ± 0.47
Limbic Lobe1.51 ± 0.58
Mesencephalon1.63 ± 0.64
Myelencephalon1.5 ± 0.62
Occipital Lobe1.5 ± 0.56
Parietal Lobe1.48 ± 0.61
Pontine Tegmentum1.53 ± 0.64
Striatum1.64 ± 0.43
Subthalamus1.63 ± 0.56
Temporal Lobe1.42 ± 0.59
Thalamus1.45 ± 0.56
White Matter2.02 ± 0.36
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Wnt7bCBCerebellum7
7.04
Wnt7bCTXCerebral cortex6.2
5.51
Wnt7bHIPHippocampal region30.6
18.65
Wnt7bHPFHippocampal formation24.57
16.25
Wnt7bHYHypothalamus1.16
0.87
Wnt7bLSXLateral septal complex0.89
0.86
Wnt7bMBMidbrain1.5
1.21
Wnt7bMYMedulla4.72
3.73
Wnt7bOLFOlfactory bulb17.4
13.74
Wnt7bPPons3.58
2.92
Wnt7bPALPallidum0.46
0.35
Wnt7bRHPRetrohippocampal region14.07
12.36
Wnt7bsAMYStriatum-like amygdalar nuclei0.53
0.38
Wnt7bSTRStriatum0.59
0.44
Wnt7bSTRdStriatum dorsal region0.39
0.27
Wnt7bSTRvStriatum ventral region1.03
0.64
Wnt7bTHThalamus0.93
0.74
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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