AutismKB 2.0

Annotation Detail for WNT2B


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Basic Information Top
Gene Symbol:WNT2B ( WNT13,XWNT2 )
Gene Full Name: wingless-type MMTV integration site family, member 2B
Band: 1p13.2
Quick LinksEntrez ID:7482; OMIM: 601968; Uniprot ID:WNT2B_HUMAN; ENSEMBL ID: ENSG00000134245; HGNC ID: 12781
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult42 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor22 / 26384583
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal33 / 33603079
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain11 / 11009899
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye5 / 21105423
heart0 / 896260 
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate2 / 18934510
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis17 / 33044251
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206459_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.9
Adipocyte4.65
AdrenalCortex5
Adrenalgland3.9
Amygdala4.95
Appendix4.8
AtrioventricularNode3.7
BDCA4+_DentriticCells5.1
Bonemarrow4.6
BronchialEpithelialCells4.65
CD105+_Endothelial4.75
CD14+_Monocytes5
CD19+_BCells(neg._sel.)5
CD33+_Myeloid5.95
CD34+5.95
CD4+_Tcells5.15
CD56+_NKCells5.7
CD71+_EarlyErythroid4.4
CD8+_Tcells4.6
CardiacMyocytes6.1
Caudatenucleus4.2
Cerebellum3.75
CerebellumPeduncles5.35
CiliaryGanglion3.25
CingulateCortex4.8
Colorectaladenocarcinoma4.7
DorsalRootGanglion3.6
FetalThyroid4.65
Fetalbrain4.7
Fetalliver4.1
Fetallung3.9
GlobusPallidus3.4
Heart5.9
Hypothalamus5.1
Kidney3.8
Leukemia_chronicMyelogenousK-5624.25
Leukemia_promyelocytic-HL-604.15
Leukemialymphoblastic(MOLT-4)3.8
Liver6.4
Lung5.15
Lymphnode4.05
Lymphoma_burkitts(Daudi)6.15
Lymphoma_burkitts(Raji)6.55
MedullaOblongata5.25
OccipitalLobe5.25
OlfactoryBulb3.7
Ovary3.15
Pancreas3.85
PancreaticIslet4.95
ParietalLobe4.9
Pituitary5.45
Placenta4.9
Pons5.1
PrefrontalCortex5.85
Prostate5.45
Salivarygland3.7
SkeletalMuscle5.65
Skin3.55
SmoothMuscle5.25
Spinalcord5
SubthalamicNucleus4.25
SuperiorCervicalGanglion5.3
TemporalLobe4.3
Testis4
TestisGermCell4
TestisIntersitial3.9
TestisLeydigCell4.65
TestisSeminiferousTubule4.2
Thalamus4.85
Thymus3.7
Thyroid5.85
Tongue4.7
Tonsil4.55
Trachea3.9
TrigeminalGanglion5.15
Uterus3.8
UterusCorpus4.15
WholeBlood5.2
Wholebrain3.9
colon4.7
pineal_day5.9
pineal_night5.74
retina9.65
small_intestine4.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6640_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.98 ± 0.63
Basal Forebrain3.86 ± 0.38
Basal Part of Pons3.73 ± 0.54
Cerebellar Cortex3.74 ± 0.72
Cerebellar Nuclei3.88 ± 0.35
Claustrum4.98 ± 0.68
Epithalamus3.19 ± 0.67
Frontal Lobe3.78 ± 0.67
Globus Pallidus4.03 ± 0.74
Hypothalamus3.15 ± 0.79
Insula3.89 ± 0.3
Limbic Lobe4 ± 0.74
Mesencephalon3.88 ± 0.54
Myelencephalon3.9 ± 0.71
Occipital Lobe3.86 ± 0.6
Parietal Lobe3.86 ± 0.69
Pontine Tegmentum3.73 ± 0.73
Striatum3.92 ± 0.69
Subthalamus3.88 ± 0.02
Temporal Lobe3.91 ± 0.65
Thalamus3.76 ± 0.62
White Matter3.84 ± 0.35
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Wnt2bCBCerebellum19.18
18.97
Wnt2bCTXCerebral cortex7.81
5.45
Wnt2bHIPHippocampal region13.47
8.72
Wnt2bHPFHippocampal formation14.04
10.74
Wnt2bHYHypothalamus11.6
8.08
Wnt2bLSXLateral septal complex1.23
1.73
Wnt2bMBMidbrain10.37
8.06
Wnt2bMYMedulla26.85
26.14
Wnt2bOLFOlfactory bulb30.56
21.89
Wnt2bPPons16.93
15.45
Wnt2bPALPallidum8.39
7.92
Wnt2bRHPRetrohippocampal region14.42
12.55
Wnt2bsAMYStriatum-like amygdalar nuclei11.98
8.12
Wnt2bSTRStriatum5.49
4.03
Wnt2bSTRdStriatum dorsal region2.79
1.95
Wnt2bSTRvStriatum ventral region13.05
9.21
Wnt2bTHThalamus6.27
4.04
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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