AutismKB 2.0

Annotation Detail for WT1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:WT1 ( AWT1,GUD,NPHS4,WAGR,WIT-2,WT33 )
Gene Full Name: Wilms tumor 1
Band: 11p13
Quick LinksEntrez ID:7490; OMIM: 607102; Uniprot ID:WT1_HUMAN; ENSEMBL ID: ENSG00000184937; HGNC ID: 12796
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus2 / 5640123
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult17 / 19391218
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal34 / 336030710
ovarian tumor3 / 7668239
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone2 / 7165527
bone marrow0 / 488010 
brain3 / 11009892
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine1 / 2344724
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary5 / 10205148
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate1 / 1893455
salivary gland1 / 2015549
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis33 / 33044299
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus10 / 23287842
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206067_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.7
Adipocyte11.7
AdrenalCortex19.95
Adrenalgland9.4
Amygdala8.35
Appendix22.25
AtrioventricularNode15.35
BDCA4+_DentriticCells8.5
Bonemarrow11.9
BronchialEpithelialCells8.8
CD105+_Endothelial9.6
CD14+_Monocytes9.95
CD19+_BCells(neg._sel.)9.3
CD33+_Myeloid12.2
CD34+11.35
CD4+_Tcells9.3
CD56+_NKCells10.45
CD71+_EarlyErythroid10.65
CD8+_Tcells7.85
CardiacMyocytes20.45
Caudatenucleus9.55
Cerebellum8.6
CerebellumPeduncles15.5
CiliaryGanglion15.8
CingulateCortex12.3
Colorectaladenocarcinoma9.75
DorsalRootGanglion13
FetalThyroid11.45
Fetalbrain10
Fetalliver9.7
Fetallung6.95
GlobusPallidus9.5
Heart21.15
Hypothalamus15.25
Kidney23.4
Leukemia_chronicMyelogenousK-56233.15
Leukemia_promyelocytic-HL-609.05
Leukemialymphoblastic(MOLT-4)23.45
Liver15.95
Lung10.85
Lymphnode7.6
Lymphoma_burkitts(Daudi)14.15
Lymphoma_burkitts(Raji)14.55
MedullaOblongata11.85
OccipitalLobe9.2
OlfactoryBulb8.1
Ovary53.15
Pancreas9.2
PancreaticIslet11.85
ParietalLobe12.65
Pituitary13.1
Placenta22.6
Pons12.75
PrefrontalCortex11
Prostate10.9
Salivarygland9.2
SkeletalMuscle23.75
Skin15.7
SmoothMuscle35.25
Spinalcord11.15
SubthalamicNucleus10.5
SuperiorCervicalGanglion33.9
TemporalLobe13.55
Testis75.9
TestisGermCell252.2
TestisIntersitial33
TestisLeydigCell38.6
TestisSeminiferousTubule52.45
Thalamus11.05
Thymus7.5
Thyroid10.3
Tongue14.8
Tonsil13.9
Trachea8.4
TrigeminalGanglion18.75
Uterus559.15
UterusCorpus74
WholeBlood10.15
Wholebrain7.55
colon9.5
pineal_day11.68
pineal_night10.82
retina12.15
small_intestine8.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16786_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.84 ± 1.12
Basal Forebrain2.31 ± 0.27
Basal Part of Pons2.28 ± 0.88
Cerebellar Cortex2.25 ± 0.89
Cerebellar Nuclei3 ± 1.49
Claustrum3.26 ± 0.94
Epithalamus2.05 ± 0.9
Frontal Lobe2.18 ± 0.73
Globus Pallidus2.56 ± 0.14
Hypothalamus2.46 ± 0.84
Insula2.06 ± 0.4
Limbic Lobe2.29 ± 0.72
Mesencephalon2.59 ± 0.81
Myelencephalon2.43 ± 0.76
Occipital Lobe2.41 ± 0.59
Parietal Lobe2.44 ± 0.95
Pontine Tegmentum2.43 ± 0.81
Striatum3.15 ± 0.71
Subthalamus2.6 ± 0.85
Temporal Lobe2.32 ± 0.76
Thalamus2.37 ± 0.6
White Matter2.64 ± 0.44
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved