AutismKB 2.0

Annotation Detail for XPNPEP2


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Basic Information Top
Gene Symbol:XPNPEP2 ( - )
Gene Full Name: X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
Band: Xq26.1
Quick LinksEntrez ID:7512; OMIM: 300145; Uniprot ID:XPP2_HUMAN; ENSEMBL ID: ENSG00000122121; HGNC ID: 12823
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult6 / 19391213
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal22 / 33603076
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain2 / 11009891
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart8 / 8962689
intestine4 / 23447217
kidney7 / 21177733
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 216910_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.1
Adipocyte46.35
AdrenalCortex6.35
Adrenalgland4.55
Amygdala5.5
Appendix5.4
AtrioventricularNode4.4
BDCA4+_DentriticCells5.2
Bonemarrow5.55
BronchialEpithelialCells5.15
CD105+_Endothelial5.6
CD14+_Monocytes5.5
CD19+_BCells(neg._sel.)5.5
CD33+_Myeloid6.6
CD34+5.6
CD4+_Tcells5.6
CD56+_NKCells6.1
CD71+_EarlyErythroid6.9
CD8+_Tcells4.75
CardiacMyocytes6.7
Caudatenucleus4.75
Cerebellum6.9
CerebellumPeduncles8.2
CiliaryGanglion11.1
CingulateCortex5.4
Colorectaladenocarcinoma4.25
DorsalRootGanglion4.4
FetalThyroid5.1
Fetalbrain5.55
Fetalliver46.25
Fetallung5.3
GlobusPallidus9.55
Heart7.05
Hypothalamus6.05
Kidney307.3
Leukemia_chronicMyelogenousK-5624.75
Leukemia_promyelocytic-HL-604.6
Leukemialymphoblastic(MOLT-4)4.15
Liver7.2
Lung5.75
Lymphnode4.4
Lymphoma_burkitts(Daudi)6.65
Lymphoma_burkitts(Raji)12.8
MedullaOblongata4.75
OccipitalLobe5.05
OlfactoryBulb5.1
Ovary3.6
Pancreas8.35
PancreaticIslet6.05
ParietalLobe5.7
Pituitary6.1
Placenta5.4
Pons5.05
PrefrontalCortex6.6
Prostate6
Salivarygland4.2
SkeletalMuscle10.6
Skin4.2
SmoothMuscle4.35
Spinalcord5.6
SubthalamicNucleus7.9
SuperiorCervicalGanglion12.35
TemporalLobe4.85
Testis4.5
TestisGermCell5.7
TestisIntersitial4.4
TestisLeydigCell5.3
TestisSeminiferousTubule4.4
Thalamus6.1
Thymus3.9
Thyroid6.25
Tongue5.4
Tonsil5.1
Trachea4.35
TrigeminalGanglion7.2
Uterus4.2
UterusCorpus4.95
WholeBlood5.7
Wholebrain4.75
colon9.95
pineal_day5.76
pineal_night5.92
retina7.075
small_intestine123.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P83659
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.43 ± 1.04
Basal Forebrain1.8 ± 0.27
Basal Part of Pons1.9 ± 0.8
Cerebellar Cortex1.95 ± 0.76
Cerebellar Nuclei2.28 ± 0.69
Claustrum2.71 ± 0.82
Epithalamus1.83 ± 0.86
Frontal Lobe1.94 ± 0.7
Globus Pallidus2.41 ± 0.68
Hypothalamus1.94 ± 0.83
Insula1.96 ± 0.67
Limbic Lobe2.07 ± 0.79
Mesencephalon2.15 ± 0.76
Myelencephalon2.13 ± 0.76
Occipital Lobe2.29 ± 0.99
Parietal Lobe1.99 ± 0.81
Pontine Tegmentum2.05 ± 0.78
Striatum2.31 ± 0.82
Subthalamus2.16 ± 0.69
Temporal Lobe1.98 ± 0.78
Thalamus2.03 ± 0.69
White Matter2.01 ± 0.23
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00803712 20 134 153 EVGTTPIVTWLLTEIPAGGR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018