AutismKB 2.0

Annotation Detail for YES1


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Basic Information Top
Gene Symbol:YES1 ( HsT441,P61-YES,Yes,c-yes )
Gene Full Name: v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
Band: 18p11.32
Quick LinksEntrez ID:7525; OMIM: 164880; Uniprot ID:YES_HUMAN; ENSEMBL ID: ENSG00000176105; HGNC ID: 12841
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst4 / 6231964
fetus16 / 56401228
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult87 / 193912144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor5 / 12794390
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor2 / 11424617
esophageal tumor4 / 17290231
gastrointestinal tumor6 / 11936950
germ cell tumor8 / 26384530
glioma1 / 1068839
head and neck tumor8 / 13630258
kidney tumor5 / 6895972
leukemia7 / 9584273
liver tumor8 / 9635983
lung tumor5 / 10312748
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal128 / 336030738
ovarian tumor3 / 7668239
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland5 / 33197150
ascites1 / 4001524
bladder1 / 2975733
blood0 / 1234780 
bone4 / 7165555
bone marrow6 / 48801122
brain24 / 110098921
cervix0 / 481710 
connective tissue0 / 1492550 
ear3 / 16212185
embryonic tissue14 / 21572264
esophagus4 / 20209197
eye3 / 21105414
heart2 / 8962622
intestine7 / 23447229
kidney14 / 21177766
larynx0 / 241450 
liver15 / 20774372
lung18 / 33697453
lymph0 / 442700 
lymph node0 / 916100 
mammary gland8 / 15327152
mouth9 / 67052134
muscle4 / 10771537
nerve0 / 157680 
ovary3 / 10205129
pancreas7 / 21481232
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta24 / 28082585
prostate3 / 18934515
salivary gland1 / 2015549
skin7 / 21057433
spleen0 / 539520 
stomach6 / 9661962
testis21 / 33044263
thymus6 / 8113173
thyroid1 / 4747321
tonsil0 / 169990 
trachea8 / 52413152
umbilical cord0 / 136800 
uterus17 / 23287872
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202932_at
Cell line Expression level Expression bar
721_B_lymphoblasts58.1
Adipocyte51.75
AdrenalCortex30.9
Adrenalgland21.9
Amygdala32.65
Appendix28.4
AtrioventricularNode45.75
BDCA4+_DentriticCells19.15
Bonemarrow23.05
BronchialEpithelialCells138.2
CD105+_Endothelial27.5
CD14+_Monocytes25.3
CD19+_BCells(neg._sel.)19.55
CD33+_Myeloid20.1
CD34+34.7
CD4+_Tcells23.75
CD56+_NKCells82.7
CD71+_EarlyErythroid20.3
CD8+_Tcells22.85
CardiacMyocytes110.25
Caudatenucleus22.1
Cerebellum17.1
CerebellumPeduncles29.4
CiliaryGanglion21.3
CingulateCortex24.55
Colorectaladenocarcinoma250.7
DorsalRootGanglion32.9
FetalThyroid33.8
Fetalbrain27.55
Fetalliver30.6
Fetallung92.4
GlobusPallidus21.15
Heart27.45
Hypothalamus43.5
Kidney20.3
Leukemia_chronicMyelogenousK-562130.85
Leukemia_promyelocytic-HL-6018.6
Leukemialymphoblastic(MOLT-4)14
Liver31.9
Lung15.35
Lymphnode23
Lymphoma_burkitts(Daudi)20.05
Lymphoma_burkitts(Raji)31.5
MedullaOblongata20.1
OccipitalLobe24.9
OlfactoryBulb21.95
Ovary16.9
Pancreas47.55
PancreaticIslet90.5
ParietalLobe22.3
Pituitary29.35
Placenta42.9
Pons22.95
PrefrontalCortex34.35
Prostate38.15
Salivarygland85.35
SkeletalMuscle33.9
Skin84.8
SmoothMuscle214.45
Spinalcord36.25
SubthalamicNucleus39.2
SuperiorCervicalGanglion32.05
TemporalLobe17.9
Testis15.2
TestisGermCell161
TestisIntersitial42.55
TestisLeydigCell55.6
TestisSeminiferousTubule27.2
Thalamus27.55
Thymus13.65
Thyroid86.45
Tongue31.05
Tonsil24.8
Trachea34
TrigeminalGanglion35.65
Uterus61.75
UterusCorpus26.95
WholeBlood12.25
Wholebrain15.6
colon163.4
pineal_day86.98
pineal_night68.8
retina42.925
small_intestine88.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P164507
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6 ± 0.41
Basal Forebrain6.26 ± 0.24
Basal Part of Pons5.7 ± 0.33
Cerebellar Cortex5.68 ± 0.34
Cerebellar Nuclei5.97 ± 0.42
Claustrum5.36 ± 0.49
Epithalamus6.6 ± 0.22
Frontal Lobe5.87 ± 0.39
Globus Pallidus7.29 ± 0.26
Hypothalamus6.13 ± 0.36
Insula5.78 ± 0.24
Limbic Lobe5.89 ± 0.46
Mesencephalon6.09 ± 0.4
Myelencephalon6.02 ± 0.5
Occipital Lobe6.04 ± 0.48
Parietal Lobe5.95 ± 0.44
Pontine Tegmentum6.07 ± 0.57
Striatum6.38 ± 0.42
Subthalamus5.74 ± 0.59
Temporal Lobe5.83 ± 0.38
Thalamus6.13 ± 0.39
White Matter7.17 ± 0.21
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Yes1CBCerebellum0
0
Yes1CTXCerebral cortex0
0
Yes1HIPHippocampal region0
0
Yes1HPFHippocampal formation0
0
Yes1HYHypothalamus0
0
Yes1LSXLateral septal complex0
0
Yes1MBMidbrain0
0
Yes1MYMedulla0
0
Yes1OLFOlfactory bulb0
0
Yes1PPons0
0
Yes1PALPallidum0
0
Yes1RHPRetrohippocampal region0
0
Yes1sAMYStriatum-like amygdalar nuclei0
0
Yes1STRStriatum0
0
Yes1STRdStriatum dorsal region0
0
Yes1STRvStriatum ventral region0
0
Yes1THThalamus0
0
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000173 13 399 411 AANILVGENLVCK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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