AutismKB 2.0

Annotation Detail for YWHAG


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:YWHAG ( 14-3-3GAMMA )
Gene Full Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
Band: 7q11.23
Quick LinksEntrez ID:7532; OMIM: 605356; Uniprot ID:1433G_HUMAN; ENSEMBL ID: ENSG00000170027; HGNC ID: 12852
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus6 / 56401210
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult8 / 19391214
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor3 / 26384511
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal37 / 336030711
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow2 / 4880140
brain44 / 110098939
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver1 / 2077434
lung0 / 3369740 
lymph0 / 442700 
lymph node1 / 9161010
mammary gland2 / 15327113
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P123022
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala11.53 ± 0.39
Basal Forebrain10.92 ± 0.33
Basal Part of Pons11.69 ± 0.38
Cerebellar Cortex10.62 ± 0.31
Cerebellar Nuclei10.97 ± 0.45
Claustrum11.87 ± 0.63
Epithalamus9.48 ± 1.04
Frontal Lobe11.09 ± 0.57
Globus Pallidus10.74 ± 0.58
Hypothalamus10.69 ± 0.63
Insula11.22 ± 0.48
Limbic Lobe11.55 ± 0.48
Mesencephalon11.01 ± 0.67
Myelencephalon11.12 ± 0.59
Occipital Lobe11.42 ± 0.46
Parietal Lobe11.28 ± 0.59
Pontine Tegmentum11 ± 0.48
Striatum10.74 ± 0.67
Subthalamus11.07 ± 0.21
Temporal Lobe11.26 ± 0.47
Thalamus11.13 ± 0.4
White Matter9.36 ± 0.85
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
YwhagCBCerebellum61.53
83.66
YwhagCTXCerebral cortex100
100
YwhagHIPHippocampal region100
100
YwhagHPFHippocampal formation100
100
YwhagHYHypothalamus100
100
YwhagLSXLateral septal complex95
90.06
YwhagMBMidbrain100
100
YwhagMYMedulla95.7
100
YwhagOLFOlfactory bulb100
100
YwhagPPons96.84
100
YwhagPALPallidum96.12
100
YwhagRHPRetrohippocampal region100
100
YwhagsAMYStriatum-like amygdalar nuclei100
100
YwhagSTRStriatum76.9
77.09
YwhagSTRdStriatum dorsal region60.13
62.05
YwhagSTRvStriatum ventral region81.77
73.97
YwhagTHThalamus97.51
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
1433G_HUMAN_0 0 0 0 DSTLIMQLLR PRIDE
1433G_HUMAN_0 0 0 0 LAEQAERYDDMAAAMK PRIDE
1433G_HUMAN_0 0 0 0 NVTELNEPLSNEER PRIDE
1433G_HUMAN_0 0 0 0 YLAEVATGEK PRIDE
1433G_HUMAN_0 0 0 0 YLAEVATGEKR PRIDE
1433G_HUMAN_1 11 1 11 VDREQLVQKAR PRIDE
1433G_HUMAN_12 16 12 27 LAEQAERYDDMAAAMK PRIDE
1433G_HUMAN_125 7 125 131 MKGDYYR PRIDE
1433G_HUMAN_132 10 132 141 YLAEVATGEK PRIDE
1433G_HUMAN_132 11 132 142 YLAEVATGEKR PRIDE
1433G_HUMAN_133 10 133 142 YLAEVATGEK PRIDE
1433G_HUMAN_144 19 144 162 ATVVESSEKAYSEAHEISK PRIDE
1433G_HUMAN_152 20 152 171 AYSEAHEISKEHMQPTHPIR PRIDE
1433G_HUMAN_162 10 162 171 EHMQPTHPIR PRIDE
1433G_HUMAN_172 26 172 197 LGLALNYSVFYYEIQNAPEQACHLAK PRIDE
1433G_HUMAN_198 19 198 216 TAFDDAIAELDTLNEDSYK PRIDE
1433G_HUMAN_198 29 198 226 TAFDDAIAELDTLNEDSYKDSTLIMQLLR PRIDE
1433G_HUMAN_199 19 199 217 TAFDDAIAELDTLNEDSYK PRIDE
1433G_HUMAN_217 10 217 226 DSTLIMQLLR PRIDE
1433G_HUMAN_218 10 218 227 DSTLIMQLLR PRIDE
1433G_HUMAN_28 14 28 41 NVTELNEPLSNEER PRIDE
1433G_HUMAN_29 14 29 42 NVTELNEPLSNEER PRIDE
1433G_HUMAN_42 14 42 55 NLLSVAYKNVVGAR PRIDE
1433G_HUMAN_42 8 42 49 NLLSVAYK PRIDE
1433G_HUMAN_43 8 43 50 NLLSVAYK PRIDE
1433G_HUMAN_5 6 5 10 EQLVQK PRIDE
1433G_HUMAN_61 16 61 76 VISSIEQKTSADGNEK PRIDE
1433G_HUMAN_61 8 61 68 VISSIEQK PRIDE
1433G_HUMAN_88 22 88 109 IEKELEAVCQDVLSLLDNYLIK PRIDE
1433G_HUMAN_91 19 91 109 ELEAVCQDVLSLLDNYLIK PRIDE
PAp00002129 19 92 110 ELEAVCQDVLSLLDNYLIK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018