AutismKB 2.0

Annotation Detail for ZFP36


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Basic Information Top
Gene Symbol:ZFP36 ( G0S24,GOS24,NUP475,RNF162A,TIS11,TTP )
Gene Full Name: zinc finger protein 36, C3H type, homolog (mouse)
Band: 19q13.1
Quick LinksEntrez ID:7538; OMIM: 190700; Uniprot ID:TTP_HUMAN; ENSEMBL ID: ENSG00000128016; HGNC ID: 12862
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst1 / 6231916
fetus23 / 56401240
neonate0 / 310970 
infant0 / 236200 
juvenile12 / 55556215
adult354 / 1939121182
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma3 / 17475171
breast (mammary gland) tumor2 / 9417821
cervical tumor2 / 3436658
chondrosarcoma13 / 82823156
colorectal tumor17 / 114246148
esophageal tumor0 / 172900 
gastrointestinal tumor20 / 119369167
germ cell tumor9 / 26384534
glioma8 / 10688374
head and neck tumor3 / 13630222
kidney tumor2 / 6895929
leukemia10 / 95842104
liver tumor5 / 9635951
lung tumor6 / 10312758
lymphoma3 / 7175541
non-neoplasia6 / 9725061
normal411 / 3360307122
ovarian tumor11 / 76682143
pancreatic tumor13 / 104616124
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor21 / 90257232
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland2 / 3319760
ascites3 / 4001574
bladder1 / 2975733
blood8 / 12347864
bone3 / 7165541
bone marrow1 / 4880120
brain41 / 110098937
cervix8 / 48171166
connective tissue18 / 149255120
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye15 / 21105471
heart2 / 8962622
intestine39 / 234472166
kidney25 / 211777118
larynx0 / 241450 
liver16 / 20774377
lung32 / 33697494
lymph1 / 4427022
lymph node7 / 9161076
mammary gland10 / 15327165
mouth0 / 670520 
muscle3 / 10771527
nerve11 / 15768697
ovary11 / 102051107
pancreas68 / 214812316
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland1 / 1658560
placenta67 / 280825238
prostate8 / 18934542
salivary gland0 / 201550 
skin6 / 21057428
spleen1 / 5395218
stomach24 / 96619248
testis18 / 33044254
thymus5 / 8113161
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus31 / 232878133
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201531_at
Cell line Expression level Expression bar
721_B_lymphoblasts381.7
Adipocyte289.85
AdrenalCortex1293.15
Adrenalgland636
Amygdala202.6
Appendix1879.15
AtrioventricularNode903.05
BDCA4+_DentriticCells3315.8
Bonemarrow1100.7
BronchialEpithelialCells172.7
CD105+_Endothelial528.2
CD14+_Monocytes3537.5
CD19+_BCells(neg._sel.)1385.65
CD33+_Myeloid6186.2
CD34+506.95
CD4+_Tcells1045.35
CD56+_NKCells2591.7
CD71+_EarlyErythroid30.7
CD8+_Tcells1055.15
CardiacMyocytes29.6
Caudatenucleus144.65
Cerebellum93.6
CerebellumPeduncles80.35
CiliaryGanglion1348.1
CingulateCortex30.1
Colorectaladenocarcinoma306.3
DorsalRootGanglion685.4
FetalThyroid328.95
Fetalbrain249.95
Fetalliver73.9
Fetallung1747.5
GlobusPallidus124.45
Heart278.8
Hypothalamus395.9
Kidney357.95
Leukemia_chronicMyelogenousK-56258.55
Leukemia_promyelocytic-HL-6037
Leukemialymphoblastic(MOLT-4)72.7
Liver271.55
Lung3738.4
Lymphnode1318.65
Lymphoma_burkitts(Daudi)108.95
Lymphoma_burkitts(Raji)134.25
MedullaOblongata161.95
OccipitalLobe212.9
OlfactoryBulb2136.95
Ovary445.8
Pancreas444.1
PancreaticIslet801.3
ParietalLobe119.15
Pituitary445.25
Placenta539.6
Pons137.7
PrefrontalCortex121.55
Prostate1179.55
Salivarygland419.35
SkeletalMuscle385.9
Skin942.8
SmoothMuscle26.95
Spinalcord1188.25
SubthalamicNucleus44.6
SuperiorCervicalGanglion1158.75
TemporalLobe120.95
Testis128.65
TestisGermCell1252.5
TestisIntersitial377.4
TestisLeydigCell304.5
TestisSeminiferousTubule167.25
Thalamus89.65
Thymus887.5
Thyroid1979.1
Tongue756.95
Tonsil756.25
Trachea2063.2
TrigeminalGanglion1274.9
Uterus851.95
UterusCorpus747.15
WholeBlood1967.75
Wholebrain58.4
colon503.85
pineal_day183.2
pineal_night223.14
retina1256.4
small_intestine454
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16771_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.28 ± 0.61
Basal Forebrain6.11 ± 0.25
Basal Part of Pons6 ± 0.59
Cerebellar Cortex5.51 ± 0.66
Cerebellar Nuclei6.06 ± 0.38
Claustrum6.52 ± 0.78
Epithalamus5.4 ± 0.74
Frontal Lobe5.85 ± 0.64
Globus Pallidus6.69 ± 0.43
Hypothalamus5.69 ± 0.67
Insula5.71 ± 0.54
Limbic Lobe6.03 ± 0.68
Mesencephalon6.04 ± 0.6
Myelencephalon5.96 ± 0.7
Occipital Lobe5.89 ± 0.71
Parietal Lobe5.81 ± 0.6
Pontine Tegmentum5.66 ± 0.58
Striatum6.06 ± 0.53
Subthalamus5.48 ± 0.95
Temporal Lobe5.78 ± 0.69
Thalamus5.91 ± 0.55
White Matter6.24 ± 0.53
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zfp36CBCerebellum7.1
8.9
Zfp36CTXCerebral cortex16.3
12.42
Zfp36HIPHippocampal region13.15
12.77
Zfp36HPFHippocampal formation12.41
11.64
Zfp36HYHypothalamus8.34
7.71
Zfp36LSXLateral septal complex3.09
2.3
Zfp36MBMidbrain6.26
7.37
Zfp36MYMedulla6.06
7
Zfp36OLFOlfactory bulb22.32
17.76
Zfp36PPons7.77
11.3
Zfp36PALPallidum12.72
11.05
Zfp36RHPRetrohippocampal region11.48
10.18
Zfp36sAMYStriatum-like amygdalar nuclei21.33
14.84
Zfp36STRStriatum11.12
7.93
Zfp36STRdStriatum dorsal region10.29
7.46
Zfp36STRvStriatum ventral region10.98
7.35
Zfp36THThalamus12.47
11.03
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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