AutismKB 2.0

Annotation Detail for ZFPL1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ZFPL1 ( D11S750,MCG4 )
Gene Full Name: zinc finger protein-like 1
Band: 11q13.1
Quick LinksEntrez ID:7542; OMIM: NA; Uniprot ID:ZFPL1_HUMAN; ENSEMBL ID: ENSG00000162300; HGNC ID: 12868
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst3 / 6231948
fetus27 / 56401247
neonate0 / 310970 
infant2 / 2362084
juvenile2 / 5555635
adult108 / 193912155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor3 / 3436687
chondrosarcoma9 / 82823108
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor12 / 26384545
glioma24 / 106883224
head and neck tumor6 / 13630244
kidney tumor6 / 6895987
leukemia3 / 9584231
liver tumor2 / 9635920
lung tumor8 / 10312777
lymphoma1 / 7175513
non-neoplasia7 / 9725071
normal160 / 336030747
ovarian tumor3 / 7668239
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS10 / 12568079
prostate cancer9 / 10268087
retinoblastoma2 / 4635643
skin tumor5 / 12494940
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood3 / 12347824
bone7 / 7165597
bone marrow0 / 488010 
brain77 / 110098969
cervix3 / 4817162
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye13 / 21105461
heart6 / 8962666
intestine24 / 234472102
kidney17 / 21177780
larynx0 / 241450 
liver2 / 2077439
lung33 / 33697497
lymph1 / 4427022
lymph node4 / 9161043
mammary gland5 / 15327132
mouth2 / 6705229
muscle5 / 10771546
nerve1 / 1576863
ovary5 / 10205148
pancreas15 / 21481269
parathyroid6 / 20539292
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta9 / 28082532
prostate20 / 189345105
salivary gland2 / 2015599
skin7 / 21057433
spleen6 / 53952111
stomach3 / 9661931
testis11 / 33044233
thymus5 / 8113161
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus14 / 23287860
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209428_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts19.8
Adipocyte11.25
AdrenalCortex11.15
Adrenalgland10
Amygdala9.9
Appendix11.2
AtrioventricularNode6.6
BDCA4+_DentriticCells8.15
Bonemarrow8.3
BronchialEpithelialCells11.1
CD105+_Endothelial8.25
CD14+_Monocytes10.15
CD19+_BCells(neg._sel.)7.2
CD33+_Myeloid10.15
CD34+10.4
CD4+_Tcells12.9
CD56+_NKCells10.2
CD71+_EarlyErythroid9
CD8+_Tcells10.9
CardiacMyocytes25.15
Caudatenucleus12.2
Cerebellum9.8
CerebellumPeduncles13.1
CiliaryGanglion5.45
CingulateCortex12.9
Colorectaladenocarcinoma26.35
DorsalRootGanglion5.75
FetalThyroid12.25
Fetalbrain9.85
Fetalliver8.8
Fetallung7.3
GlobusPallidus6.65
Heart11.4
Hypothalamus14.2
Kidney9.5
Leukemia_chronicMyelogenousK-56221.45
Leukemia_promyelocytic-HL-608.45
Leukemialymphoblastic(MOLT-4)8.5
Liver32.85
Lung30.55
Lymphnode9.9
Lymphoma_burkitts(Daudi)10.45
Lymphoma_burkitts(Raji)13.85
MedullaOblongata10.05
OccipitalLobe10.2
OlfactoryBulb7.3
Ovary6.9
Pancreas7.85
PancreaticIslet12.9
ParietalLobe10.15
Pituitary11.45
Placenta14.95
Pons9.95
PrefrontalCortex11.35
Prostate11.9
Salivarygland7.05
SkeletalMuscle13.3
Skin6.1
SmoothMuscle16.2
Spinalcord12.65
SubthalamicNucleus7.8
SuperiorCervicalGanglion11
TemporalLobe9.9
Testis17.1
TestisGermCell9.7
TestisIntersitial12.1
TestisLeydigCell15.95
TestisSeminiferousTubule15.6
Thalamus10.45
Thymus8.85
Thyroid15.95
Tongue9.65
Tonsil9.4
Trachea7.9
TrigeminalGanglion9.35
Uterus9.75
UterusCorpus11.05
WholeBlood12.8
Wholebrain9.5
colon10.4
pineal_day10.44
pineal_night9.98
retina14.775
small_intestine14.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5079_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.56 ± 0.6
Basal Forebrain4.49 ± 0.48
Basal Part of Pons4.46 ± 0.51
Cerebellar Cortex4.35 ± 0.46
Cerebellar Nuclei4.47 ± 0.69
Claustrum4.59 ± 0.66
Epithalamus4.01 ± 0.42
Frontal Lobe4.52 ± 0.5
Globus Pallidus4.97 ± 0.52
Hypothalamus4.27 ± 0.67
Insula4.5 ± 0.59
Limbic Lobe4.62 ± 0.56
Mesencephalon4.5 ± 0.58
Myelencephalon4.57 ± 0.56
Occipital Lobe4.33 ± 0.6
Parietal Lobe4.51 ± 0.45
Pontine Tegmentum4.39 ± 0.55
Striatum4.62 ± 0.54
Subthalamus3.9 ± 1.04
Temporal Lobe4.51 ± 0.53
Thalamus4.55 ± 0.37
White Matter5.23 ± 0.18
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zfpl1CBCerebellum2.75
3.45
Zfpl1CTXCerebral cortex16.63
12.13
Zfpl1HIPHippocampal region15.64
15.01
Zfpl1HPFHippocampal formation14.27
12.86
Zfpl1HYHypothalamus0.11
0.1
Zfpl1LSXLateral septal complex0.13
0.08
Zfpl1MBMidbrain0.28
0.71
Zfpl1MYMedulla0.25
0.25
Zfpl1OLFOlfactory bulb8.68
6.43
Zfpl1PPons0.62
1.63
Zfpl1PALPallidum0.95
0.81
Zfpl1RHPRetrohippocampal region12.33
10.04
Zfpl1sAMYStriatum-like amygdalar nuclei0.85
0.51
Zfpl1STRStriatum1.81
1.31
Zfpl1STRdStriatum dorsal region2.41
1.77
Zfpl1STRvStriatum ventral region0.69
0.52
Zfpl1THThalamus1.29
1.12
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00001552 18 219 236 DDDRTPGLHGDCDDDKYR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018