AutismKB 2.0

Annotation Detail for CA3


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Basic Information Top
Gene Symbol:CA3 ( CAIII,Car3 )
Gene Full Name: carbonic anhydrase III, muscle specific
Band: 8q21.2
Quick LinksEntrez ID:761; OMIM: 114750; Uniprot ID:CAH3_HUMAN; ENSEMBL ID: ENSG00000164879; HGNC ID: 1374
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus43 / 56401276
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult41 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal604 / 3360307179
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue4 / 13106305
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood5 / 12347840
bone0 / 716550 
bone marrow0 / 488010 
brain6 / 11009895
cervix1 / 4817120
connective tissue0 / 1492550 
ear16 / 16212986
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye10 / 21105447
heart92 / 896261026
intestine0 / 2344720 
kidney1 / 2117774
larynx4 / 24145165
liver9 / 20774343
lung7 / 33697420
lymph0 / 442700 
lymph node1 / 9161010
mammary gland1 / 1532716
mouth1 / 6705214
muscle475 / 1077154409
nerve1 / 1576863
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate5 / 18934526
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis4 / 33044212
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204865_at
Cell line Expression level Expression bar
721_B_lymphoblasts12.15
Adipocyte12.5
AdrenalCortex19.5
Adrenalgland12.95
Amygdala10.85
Appendix25.7
AtrioventricularNode26.65
BDCA4+_DentriticCells12.7
Bonemarrow20.15
BronchialEpithelialCells11.85
CD105+_Endothelial22.5
CD14+_Monocytes18.25
CD19+_BCells(neg._sel.)13.7
CD33+_Myeloid16.9
CD34+14.65
CD4+_Tcells11.65
CD56+_NKCells14.25
CD71+_EarlyErythroid55.8
CD8+_Tcells10.85
CardiacMyocytes30.15
Caudatenucleus11.85
Cerebellum11.05
CerebellumPeduncles18.2
CiliaryGanglion21.9
CingulateCortex15.9
Colorectaladenocarcinoma12.85
DorsalRootGanglion19.25
FetalThyroid20.05
Fetalbrain12.4
Fetalliver11.75
Fetallung8.95
GlobusPallidus12.55
Heart28.55
Hypothalamus12.8
Kidney14.8
Leukemia_chronicMyelogenousK-56211.4
Leukemia_promyelocytic-HL-6011.45
Leukemialymphoblastic(MOLT-4)9.5
Liver22.55
Lung14.45
Lymphnode10.6
Lymphoma_burkitts(Daudi)19.5
Lymphoma_burkitts(Raji)22.2
MedullaOblongata10.75
OccipitalLobe12.4
OlfactoryBulb9.85
Ovary14.5
Pancreas12.15
PancreaticIslet14.5
ParietalLobe17.6
Pituitary15.7
Placenta11.45
Pons14.75
PrefrontalCortex14.15
Prostate25.3
Salivarygland12.55
SkeletalMuscle112.85
Skin44.75
SmoothMuscle16.05
Spinalcord13.35
SubthalamicNucleus14
SuperiorCervicalGanglion28.55
TemporalLobe14.2
Testis11.45
TestisGermCell9.6
TestisIntersitial13.35
TestisLeydigCell17.25
TestisSeminiferousTubule11.6
Thalamus14.65
Thymus9.7
Thyroid493.25
Tongue27.85
Tonsil13.9
Trachea10.95
TrigeminalGanglion29.5
Uterus10.75
UterusCorpus14.95
WholeBlood13.3
Wholebrain8.9
colon13.4
pineal_day15.64
pineal_night15.52
retina15.475
small_intestine14.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8906_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.14 ± 1.25
Basal Forebrain2.44 ± 0.27
Basal Part of Pons2.24 ± 0.34
Cerebellar Cortex2.24 ± 0.71
Cerebellar Nuclei2.88 ± 0.84
Claustrum3.17 ± 0.88
Epithalamus2.18 ± 1.01
Frontal Lobe2.18 ± 0.67
Globus Pallidus2.93 ± 0.34
Hypothalamus2.4 ± 0.57
Insula2.18 ± 0.69
Limbic Lobe2.37 ± 0.71
Mesencephalon2.49 ± 0.69
Myelencephalon2.37 ± 0.7
Occipital Lobe2.45 ± 0.78
Parietal Lobe2.44 ± 0.82
Pontine Tegmentum2.44 ± 0.8
Striatum2.55 ± 0.74
Subthalamus2.48 ± 0.75
Temporal Lobe2.28 ± 0.7
Thalamus2.3 ± 0.58
White Matter2.98 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Car3CBCerebellum0.73
1.14
Car3CTXCerebral cortex0.87
0.67
Car3HIPHippocampal region0.42
0.7
Car3HPFHippocampal formation0.53
0.68
Car3HYHypothalamus0.54
0.5
Car3LSXLateral septal complex0.36
1.08
Car3MBMidbrain0.88
0.88
Car3MYMedulla3.9
5.02
Car3OLFOlfactory bulb2.04
2.45
Car3PPons4.91
6.21
Car3PALPallidum0.57
0.61
Car3RHPRetrohippocampal region0.7
0.62
Car3sAMYStriatum-like amygdalar nuclei0.32
0.35
Car3STRStriatum0.73
0.41
Car3STRdStriatum dorsal region0.91
0.43
Car3STRvStriatum ventral region0.58
0.3
Car3THThalamus0.34
0.34
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00136019 9 68 76 VVFDDTYDR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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