AutismKB 2.0

Annotation Detail for ZNF76


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Basic Information Top
Gene Symbol:ZNF76 ( D6S229E,ZNF523,Zfp523 )
Gene Full Name: zinc finger protein 76 (expressed in testis)
Band: 6p21.31
Quick LinksEntrez ID:7629; OMIM: 194549; Uniprot ID:ZNF76_HUMAN; ENSEMBL ID: ENSG00000065029; HGNC ID: 13149
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst3 / 6231948
fetus16 / 56401228
neonate0 / 310970 
infant3 / 23620127
juvenile3 / 5555653
adult90 / 193912146
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma3 / 17475171
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma5 / 8282360
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor10 / 11936983
germ cell tumor6 / 26384522
glioma1 / 1068839
head and neck tumor4 / 13630229
kidney tumor3 / 6895943
leukemia2 / 9584220
liver tumor3 / 9635931
lung tumor6 / 10312758
lymphoma4 / 7175555
non-neoplasia3 / 9725030
normal118 / 336030735
ovarian tumor3 / 7668239
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor6 / 12494948
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites3 / 4001574
bladder1 / 2975733
blood2 / 12347816
bone5 / 7165569
bone marrow0 / 488010 
brain20 / 110098918
cervix1 / 4817120
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus0 / 202090 
eye10 / 21105447
heart1 / 8962611
intestine7 / 23447229
kidney4 / 21177718
larynx0 / 241450 
liver4 / 20774319
lung10 / 33697429
lymph2 / 4427045
lymph node4 / 9161043
mammary gland5 / 15327132
mouth0 / 670520 
muscle2 / 10771518
nerve1 / 1576863
ovary3 / 10205129
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland3 / 16585180
placenta28 / 28082599
prostate4 / 18934521
salivary gland1 / 2015549
skin9 / 21057442
spleen0 / 539520 
stomach5 / 9661951
testis11 / 33044233
thymus1 / 8113112
thyroid4 / 4747384
tonsil5 / 16999294
trachea1 / 5241319
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207494_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts46.9
Adipocyte38.95
AdrenalCortex51.2
Adrenalgland45.5
Amygdala37.35
Appendix55.45
AtrioventricularNode36.45
BDCA4+_DentriticCells36.05
Bonemarrow45.15
BronchialEpithelialCells29.85
CD105+_Endothelial40
CD14+_Monocytes43.4
CD19+_BCells(neg._sel.)60.3
CD33+_Myeloid34.1
CD34+43.8
CD4+_Tcells59.95
CD56+_NKCells54.45
CD71+_EarlyErythroid39.35
CD8+_Tcells54.4
CardiacMyocytes57.5
Caudatenucleus42.6
Cerebellum38.95
CerebellumPeduncles54.05
CiliaryGanglion40.5
CingulateCortex48.15
Colorectaladenocarcinoma37.75
DorsalRootGanglion38.7
FetalThyroid45.75
Fetalbrain38.25
Fetalliver40.5
Fetallung36.2
GlobusPallidus34.05
Heart68.1
Hypothalamus50.7
Kidney38.6
Leukemia_chronicMyelogenousK-56242.1
Leukemia_promyelocytic-HL-6042.4
Leukemialymphoblastic(MOLT-4)53.25
Liver61.8
Lung45.75
Lymphnode51.95
Lymphoma_burkitts(Daudi)61.05
Lymphoma_burkitts(Raji)69.3
MedullaOblongata42.8
OccipitalLobe41.55
OlfactoryBulb44.7
Ovary39.95
Pancreas38.6
PancreaticIslet50.05
ParietalLobe49
Pituitary57.3
Placenta51.3
Pons66.2
PrefrontalCortex47.25
Prostate43.35
Salivarygland47.25
SkeletalMuscle57.1
Skin61
SmoothMuscle47
Spinalcord49.7
SubthalamicNucleus36.95
SuperiorCervicalGanglion54.9
TemporalLobe48.4
Testis40.3
TestisGermCell39.5
TestisIntersitial39.7
TestisLeydigCell61.95
TestisSeminiferousTubule80.05
Thalamus48.85
Thymus37
Thyroid45.35
Tongue42.05
Tonsil45.2
Trachea43.5
TrigeminalGanglion72.8
Uterus32.35
UterusCorpus41.3
WholeBlood34.85
Wholebrain27.9
colon34.95
pineal_day55.1
pineal_night48.96
retina55.575
small_intestine44.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11062_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.61 ± 0.89
Basal Forebrain2.09 ± 0.57
Basal Part of Pons2.12 ± 0.63
Cerebellar Cortex2.29 ± 0.71
Cerebellar Nuclei2.39 ± 0.57
Claustrum2.67 ± 0.86
Epithalamus1.78 ± 0.85
Frontal Lobe2.1 ± 0.66
Globus Pallidus2.34 ± 0.69
Hypothalamus1.83 ± 0.74
Insula2.24 ± 0.66
Limbic Lobe2.22 ± 0.68
Mesencephalon2.23 ± 0.63
Myelencephalon2.15 ± 0.68
Occipital Lobe2.32 ± 0.65
Parietal Lobe2.21 ± 0.85
Pontine Tegmentum2.27 ± 0.81
Striatum2.37 ± 0.75
Subthalamus2.65 ± 0.99
Temporal Lobe2.08 ± 0.76
Thalamus2.16 ± 0.67
White Matter2.54 ± 0.43
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zfp523CBCerebellum32.61
36.94
Zfp523CTXCerebral cortex100
95.27
Zfp523HIPHippocampal region68.13
100
Zfp523HPFHippocampal formation72.36
87.18
Zfp523HYHypothalamus62.56
50.05
Zfp523LSXLateral septal complex90.31
65.77
Zfp523MBMidbrain54.95
48.34
Zfp523MYMedulla45.17
45.21
Zfp523OLFOlfactory bulb90.58
85.34
Zfp523PPons40.77
37.45
Zfp523PALPallidum61.72
55.91
Zfp523RHPRetrohippocampal region80.06
66.01
Zfp523sAMYStriatum-like amygdalar nuclei63.03
47.53
Zfp523STRStriatum96.25
74.62
Zfp523STRdStriatum dorsal region100
79.53
Zfp523STRvStriatum ventral region100
78.24
Zfp523THThalamus71.98
62.78
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018