Annotation Detail for CA12
Basic Information Top
| Gene Symbol: | CA12 ( CAXII,FLJ20151,HsT18816 ) |
|---|---|
| Gene Full Name: | carbonic anhydrase XII |
| Band: | 15q22.2 |
| Quick Links | Entrez ID:771; OMIM: 603263; Uniprot ID:CAH12_HUMAN; ENSEMBL ID: ENSG00000074410; HGNC ID: 1371 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.210995
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 1 / 62319 | 16 | |
| fetus | 14 / 564012 | 24 | |
| neonate | 0 / 31097 | 0 | |
| infant | 1 / 23620 | 42 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 140 / 1939121 | 72 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 28 / 94178 | 297 |  |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 23 / 82823 | 277 | |
| colorectal tumor | 22 / 114246 | 192 | |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 3 / 119369 | 25 | |
| germ cell tumor | 4 / 263845 | 15 | |
| glioma | 7 / 106883 | 65 | |
| head and neck tumor | 21 / 136302 | 154 | |
| kidney tumor | 5 / 68959 | 72 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 4 / 96359 | 41 | |
| lung tumor | 12 / 103127 | 116 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 3 / 97250 | 30 | |
| normal | 187 / 3360307 | 55 | |
| ovarian tumor | 2 / 76682 | 26 | |
| pancreatic tumor | 3 / 104616 | 28 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 1 / 102680 | 9 |  |
| retinoblastoma | 51 / 46356 | 1100 |  |
| skin tumor | 2 / 124949 | 16 | |
| soft tissue/muscle tissue tumor | 2 / 125191 | 15 | |
| uterine tumor | 8 / 90257 | 88 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 4 / 29757 | 134 | |
| blood | 0 / 123478 | 0 | |
| bone | 20 / 71655 | 279 | |
| bone marrow | 2 / 48801 | 40 | |
| brain | 64 / 1100989 | 58 | |
| cervix | 7 / 48171 | 145 | |
| connective tissue | 8 / 149255 | 53 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 5 / 215722 | 23 | |
| esophagus | 2 / 20209 | 98 | |
| eye | 63 / 211054 | 298 | |
| heart | 0 / 89626 | 0 | |
| intestine | 48 / 234472 | 204 | |
| kidney | 86 / 211777 | 406 | |
| larynx | 1 / 24145 | 41 | |
| liver | 7 / 207743 | 33 | |
| lung | 22 / 336974 | 65 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 33 / 153271 | 215 | |
| mouth | 17 / 67052 | 253 | |
| muscle | 5 / 107715 | 46 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 2 / 102051 | 19 | |
| pancreas | 8 / 214812 | 37 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 7 / 280825 | 24 | |
| prostate | 5 / 189345 | 26 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 11 / 210574 | 52 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 2 / 96619 | 20 | |
| testis | 1 / 330442 | 3 | |
| thymus | 2 / 81131 | 24 | |
| thyroid | 5 / 47473 | 105 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 1 / 52413 | 19 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 16 / 232878 | 68 | |
| vascular | 8 / 51780 | 154 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 214164_x_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 4.6 | |
| Adipocyte | 47.65 | |
| AdrenalCortex | 3.75 | |
| Adrenalgland | 3.1 | |
| Amygdala | 4.05 | |
| Appendix | 3.65 | |
| AtrioventricularNode | 2.7 | |
| BDCA4+_DentriticCells | 4.15 | |
| Bonemarrow | 3.65 | |
| BronchialEpithelialCells | 222.8 | |
| CD105+_Endothelial | 3.75 | |
| CD14+_Monocytes | 3.95 | |
| CD19+_BCells(neg._sel.) | 3.95 | |
| CD33+_Myeloid | 4.85 | |
| CD34+ | 4.7 | |
| CD4+_Tcells | 4.1 | |
| CD56+_NKCells | 4.45 | |
| CD71+_EarlyErythroid | 3.45 | |
| CD8+_Tcells | 3.55 | |
| CardiacMyocytes | 4.65 | |
| Caudatenucleus | 221.4 | |
| Cerebellum | 3.05 | |
| CerebellumPeduncles | 4.2 | |
| CiliaryGanglion | 2.55 | |
| CingulateCortex | 3.75 | |
| Colorectaladenocarcinoma | 3.7 | |
| DorsalRootGanglion | 2.75 | |
| FetalThyroid | 3.6 | |
| Fetalbrain | 3.75 | |
| Fetalliver | 3.15 | |
| Fetallung | 4.65 | |
| GlobusPallidus | 2.7 | |
| Heart | 4.65 | |
| Hypothalamus | 10.3 | |
| Kidney | 651.15 | |
| Leukemia_chronicMyelogenousK-562 | 3.3 | |
| Leukemia_promyelocytic-HL-60 | 3.25 | |
| Leukemialymphoblastic(MOLT-4) | 3.05 | |
| Liver | 4.8 | |
| Lung | 4.15 | |
| Lymphnode | 3.25 | |
| Lymphoma_burkitts(Daudi) | 4.7 | |
| Lymphoma_burkitts(Raji) | 5.1 | |
| MedullaOblongata | 29.6 | |
| OccipitalLobe | 3.35 | |
| OlfactoryBulb | 2.9 | |
| Ovary | 2.45 | |
| Pancreas | 30.1 | |
| PancreaticIslet | 57.8 | |
| ParietalLobe | 3.85 | |
| Pituitary | 7.3 | |
| Placenta | 3.9 | |
| Pons | 3.6 | |
| PrefrontalCortex | 4.7 | |
| Prostate | 7.45 | |
| Salivarygland | 3 | |
| SkeletalMuscle | 4.2 | |
| Skin | 52.35 | |
| SmoothMuscle | 356.85 | |
| Spinalcord | 3.9 | |
| SubthalamicNucleus | 3.3 | |
| SuperiorCervicalGanglion | 4.15 | |
| TemporalLobe | 3.4 | |
| Testis | 3.2 | |
| TestisGermCell | 3.15 | |
| TestisIntersitial | 3.1 | |
| TestisLeydigCell | 3.65 | |
| TestisSeminiferousTubule | 3.25 | |
| Thalamus | 29.9 | |
| Thymus | 2.9 | |
| Thyroid | 4.75 | |
| Tongue | 70.1 | |
| Tonsil | 8.5 | |
| Trachea | 3.35 | |
| TrigeminalGanglion | 3.65 | |
| Uterus | 6.45 | |
| UterusCorpus | 39.95 | |
| WholeBlood | 4 | |
| Wholebrain | 3.25 | |
| colon | 680.15 | |
| pineal_day | 4.7 | |
| pineal_night | 26.62 | |
| retina | 40.225 | |
| small_intestine | 4.15 | |
- Probe name: CUST_5_PI416408490
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.02 ± 1.05 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 5.06 ± 0.47 | |
| Basal Part of Pons | 4.18 ± 1.34 | |
| Cerebellar Cortex | 3.99 ± 0.39 | |
| Cerebellar Nuclei | 4.04 ± 1.12 | |
| Claustrum | 5.31 ± 0.84 | |
| Epithalamus | 3.53 ± 1.55 | |
| Frontal Lobe | 4.12 ± 1.12 | |
| Globus Pallidus | 5.3 ± 0.44 | |
| Hypothalamus | 4.01 ± 0.86 | |
| Insula | 3.68 ± 1.29 | |
| Limbic Lobe | 4.49 ± 1.25 | |
| Mesencephalon | 5.03 ± 0.92 | |
| Myelencephalon | 4.63 ± 1.34 | |
| Occipital Lobe | 4.7 ± 1.31 | |
| Parietal Lobe | 4.55 ± 1.26 | |
| Pontine Tegmentum | 4.53 ± 1.07 | |
| Striatum | 7.27 ± 0.79 | |
| Subthalamus | 4.35 ± 1.49 | |
| Temporal Lobe | 4.38 ± 1.09 | |
| Thalamus | 5.18 ± 0.67 | |
| White Matter | 4.6 ± 0.78 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Car12 | CB | Cerebellum | 8.48 | |
| 11.37 | | |||
| Car12 | CTX | Cerebral cortex | 19.78 | |
| 14.07 | | |||
| Car12 | HIP | Hippocampal region | 49.95 | |
| 81.56 | | |||
| Car12 | HPF | Hippocampal formation | 38.85 | |
| 55.91 | | |||
| Car12 | HY | Hypothalamus | 1.15 | |
| 0.93 | | |||
| Car12 | LSX | Lateral septal complex | 13.78 | |
| 11.8 | | |||
| Car12 | MB | Midbrain | 1.97 | |
| 1.84 | | |||
| Car12 | MY | Medulla | 10.69 | |
| 14.24 | | |||
| Car12 | OLF | Olfactory bulb | 33.39 | |
| 26.53 | | |||
| Car12 | P | Pons | 2.26 | |
| 2.2 | | |||
| Car12 | PAL | Pallidum | 7.49 | |
| 6.2 | | |||
| Car12 | RHP | Retrohippocampal region | 21.15 | |
| 18.95 | | |||
| Car12 | sAMY | Striatum-like amygdalar nuclei | 10.23 | |
| 9.19 | | |||
| Car12 | STR | Striatum | 83.2 | |
| 60.95 | | |||
| Car12 | STRd | Striatum dorsal region | 97.33 | |
| 72.76 | | |||
| Car12 | STRv | Striatum ventral region | 100 | |
| 67.72 | | |||
| Car12 | TH | Thalamus | 3.86 | |
| 6.36 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00848643 | 28 | 241 | 268 | NPVQISQEQLLALETALYCTHMDDPSPR | Peptide Atlas |