AutismKB 2.0

Annotation Detail for ZNF174


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Basic Information Top
Gene Symbol:ZNF174 ( ZSCAN8 )
Gene Full Name: zinc finger protein 174
Band: 16p13.3
Quick LinksEntrez ID:7727; OMIM: 603900; Uniprot ID:ZN174_HUMAN; ENSEMBL ID: ENSG00000103343; HGNC ID: 12963
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus10 / 56401217
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult31 / 193912115
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor4 / 34366116
chondrosarcoma4 / 8282348
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor11 / 26384541
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal67 / 336030719
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone2 / 7165527
bone marrow0 / 488010 
brain18 / 110098916
cervix4 / 4817183
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye5 / 21105423
heart0 / 896260 
intestine4 / 23447217
kidney10 / 21177747
larynx0 / 241450 
liver0 / 2077430 
lung17 / 33697450
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth5 / 6705274
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate1 / 1893455
salivary gland0 / 201550 
skin4 / 21057418
spleen1 / 5395218
stomach1 / 9661910
testis11 / 33044233
thymus4 / 8113149
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210291_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts11.15
Adipocyte8.85
AdrenalCortex10.15
Adrenalgland7.65
Amygdala8.95
Appendix9.1
AtrioventricularNode6.95
BDCA4+_DentriticCells8.1
Bonemarrow9.1
BronchialEpithelialCells8.75
CD105+_Endothelial8.65
CD14+_Monocytes9.55
CD19+_BCells(neg._sel.)9.25
CD33+_Myeloid10.1
CD34+9.85
CD4+_Tcells9.6
CD56+_NKCells9.05
CD71+_EarlyErythroid8.45
CD8+_Tcells7.9
CardiacMyocytes12.45
Caudatenucleus8.1
Cerebellum13.6
CerebellumPeduncles11.05
CiliaryGanglion6.45
CingulateCortex9.2
Colorectaladenocarcinoma8.95
DorsalRootGanglion6.9
FetalThyroid8.75
Fetalbrain8.85
Fetalliver7.55
Fetallung7.25
GlobusPallidus8.1
Heart17.85
Hypothalamus9.65
Kidney8.1
Leukemia_chronicMyelogenousK-56210.7
Leukemia_promyelocytic-HL-608.55
Leukemialymphoblastic(MOLT-4)7.45
Liver12.25
Lung9.1
Lymphnode7.55
Lymphoma_burkitts(Daudi)12.15
Lymphoma_burkitts(Raji)12.65
MedullaOblongata9.4
OccipitalLobe9.2
OlfactoryBulb7.1
Ovary6.8
Pancreas7.25
PancreaticIslet9.5
ParietalLobe11.6
Pituitary10.5
Placenta8.7
Pons10.5
PrefrontalCortex10.95
Prostate10.3
Salivarygland6.95
SkeletalMuscle22.5
Skin6.95
SmoothMuscle10.1
Spinalcord10.55
SubthalamicNucleus10.6
SuperiorCervicalGanglion10.2
TemporalLobe13.65
Testis8.55
TestisGermCell6.9
TestisIntersitial7.15
TestisLeydigCell9.8
TestisSeminiferousTubule7.65
Thalamus15.95
Thymus6.8
Thyroid10.55
Tongue8.95
Tonsil8.7
Trachea7.5
TrigeminalGanglion9.55
Uterus7.1
UterusCorpus11.75
WholeBlood9.55
Wholebrain8.7
colon8.6
pineal_day11.82
pineal_night10.94
retina11.225
small_intestine8.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P49327
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.11 ± 0.65
Basal Forebrain3.6 ± 0.41
Basal Part of Pons4.31 ± 0.52
Cerebellar Cortex4.3 ± 0.37
Cerebellar Nuclei3.96 ± 0.46
Claustrum3.93 ± 0.62
Epithalamus3.82 ± 0.65
Frontal Lobe4.12 ± 0.49
Globus Pallidus3.56 ± 0.32
Hypothalamus3.9 ± 0.49
Insula4.19 ± 0.36
Limbic Lobe3.92 ± 0.56
Mesencephalon4.08 ± 0.6
Myelencephalon3.95 ± 0.53
Occipital Lobe3.67 ± 0.5
Parietal Lobe3.98 ± 0.48
Pontine Tegmentum3.9 ± 0.47
Striatum3.58 ± 0.54
Subthalamus4.08 ± 0.32
Temporal Lobe4.13 ± 0.46
Thalamus3.93 ± 0.5
White Matter3.67 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zfp174CBCerebellum4.63
5.57
Zfp174CTXCerebral cortex6.01
4.61
Zfp174HIPHippocampal region4.02
3.74
Zfp174HPFHippocampal formation4.03
3.51
Zfp174HYHypothalamus1.24
1.14
Zfp174LSXLateral septal complex0.53
1.07
Zfp174MBMidbrain2.4
2.58
Zfp174MYMedulla6.59
7.39
Zfp174OLFOlfactory bulb7.49
6.31
Zfp174PPons5.2
5.35
Zfp174PALPallidum2
1.72
Zfp174RHPRetrohippocampal region4.03
3.14
Zfp174sAMYStriatum-like amygdalar nuclei2.39
1.84
Zfp174STRStriatum1.78
1.43
Zfp174STRdStriatum dorsal region1.52
1.26
Zfp174STRvStriatum ventral region2.7
1.82
Zfp174THThalamus1.91
1.94
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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