AutismKB 2.0

Annotation Detail for LUZP1


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Basic Information Top
Gene Symbol:LUZP1 ( FLJ35697,KIAA0601,LUZP )
Gene Full Name: leucine zipper protein 1
Band: 1p36.12
Quick LinksEntrez ID:7798; OMIM: 601422; Uniprot ID:LUZP1_HUMAN; ENSEMBL ID: ENSG00000169641; HGNC ID: 14985
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst1 / 6231916
fetus17 / 56401230
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult84 / 193912143
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor2 / 3436658
chondrosarcoma5 / 8282360
colorectal tumor19 / 114246166
esophageal tumor1 / 1729057
gastrointestinal tumor2 / 11936916
germ cell tumor13 / 26384549
glioma4 / 10688337
head and neck tumor11 / 13630280
kidney tumor4 / 6895958
leukemia1 / 9584210
liver tumor3 / 9635931
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal104 / 336030730
ovarian tumor3 / 7668239
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder1 / 2975733
blood3 / 12347824
bone4 / 7165555
bone marrow0 / 488010 
brain33 / 110098929
cervix2 / 4817141
connective tissue3 / 14925520
ear1 / 1621261
embryonic tissue7 / 21572232
esophagus1 / 2020949
eye12 / 21105456
heart2 / 8962622
intestine29 / 234472123
kidney7 / 21177733
larynx1 / 2414541
liver6 / 20774328
lung21 / 33697462
lymph0 / 442700 
lymph node0 / 916100 
mammary gland5 / 15327132
mouth6 / 6705289
muscle5 / 10771546
nerve0 / 157680 
ovary2 / 10205119
pancreas12 / 21481255
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta10 / 28082535
prostate3 / 18934515
salivary gland1 / 2015549
skin7 / 21057433
spleen3 / 5395255
stomach1 / 9661910
testis9 / 33044227
thymus5 / 8113161
thyroid5 / 47473105
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus6 / 23287825
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221831_at
Cell line Expression level Expression bar
721_B_lymphoblasts49.15
Adipocyte34.6
AdrenalCortex47
Adrenalgland31.55
Amygdala39.35
Appendix43.1
AtrioventricularNode41.25
BDCA4+_DentriticCells19.05
Bonemarrow42.1
BronchialEpithelialCells42.95
CD105+_Endothelial24.3
CD14+_Monocytes26.75
CD19+_BCells(neg._sel.)25.65
CD33+_Myeloid23.8
CD34+41.1
CD4+_Tcells35.6
CD56+_NKCells22.05
CD71+_EarlyErythroid34.4
CD8+_Tcells30
CardiacMyocytes50.95
Caudatenucleus33.65
Cerebellum32.4
CerebellumPeduncles49.75
CiliaryGanglion29.35
CingulateCortex38.95
Colorectaladenocarcinoma37.6
DorsalRootGanglion30.95
FetalThyroid39
Fetalbrain36.2
Fetalliver37.5
Fetallung29.85
GlobusPallidus28.35
Heart49.3
Hypothalamus37.4
Kidney33.65
Leukemia_chronicMyelogenousK-56232.65
Leukemia_promyelocytic-HL-6031.4
Leukemialymphoblastic(MOLT-4)31.15
Liver56.3
Lung39.5
Lymphnode30.7
Lymphoma_burkitts(Daudi)47.35
Lymphoma_burkitts(Raji)76.2
MedullaOblongata34.35
OccipitalLobe31.8
OlfactoryBulb29
Ovary28.9
Pancreas34.1
PancreaticIslet40.15
ParietalLobe41.7
Pituitary53.45
Placenta34.45
Pons36
PrefrontalCortex57.9
Prostate40.6
Salivarygland30.1
SkeletalMuscle44.4
Skin35.1
SmoothMuscle39.5
Spinalcord39.35
SubthalamicNucleus39.6
SuperiorCervicalGanglion66.2
TemporalLobe33.95
Testis33.9
TestisGermCell30.15
TestisIntersitial37.1
TestisLeydigCell38.35
TestisSeminiferousTubule32.05
Thalamus37.55
Thymus29.25
Thyroid45.3
Tongue40.8
Tonsil36.8
Trachea30.85
TrigeminalGanglion41.9
Uterus27.6
UterusCorpus33.6
WholeBlood37.55
Wholebrain27.85
colon44.55
pineal_day40.4
pineal_night40.16
retina40.2
small_intestine47.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P407142
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.33 ± 0.85
Basal Forebrain2.87 ± 0.29
Basal Part of Pons4.1 ± 0.6
Cerebellar Cortex3.17 ± 0.85
Cerebellar Nuclei3.47 ± 0.52
Claustrum2.98 ± 0.78
Epithalamus2.74 ± 0.85
Frontal Lobe3.53 ± 0.8
Globus Pallidus2.32 ± 0.67
Hypothalamus2.91 ± 0.56
Insula3.13 ± 0.86
Limbic Lobe2.98 ± 0.78
Mesencephalon3.16 ± 0.77
Myelencephalon3.25 ± 0.83
Occipital Lobe3.07 ± 0.77
Parietal Lobe3.55 ± 0.79
Pontine Tegmentum3.03 ± 0.5
Striatum2.46 ± 0.83
Subthalamus3.39 ± 0.87
Temporal Lobe3.36 ± 0.64
Thalamus3.36 ± 0.72
White Matter1.65 ± 0.58
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00011862 29 149 177 VGDTITVAAWNHSASMEEEGEDCTLSVYR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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