AutismKB 2.0

Annotation Detail for DNALI1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:DNALI1 ( P28,dJ423B22.5,hp28 )
Gene Full Name: dynein, axonemal, light intermediate chain 1
Band: 1p34.3
Quick LinksEntrez ID:7802; OMIM: 602135; Uniprot ID:IDLC_HUMAN; ENSEMBL ID: ENSG00000163879; HGNC ID: 14353
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus24 / 56401242
neonate1 / 3109732
infant0 / 236200 
juvenile1 / 5555617
adult69 / 193912135
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor4 / 26384515
glioma5 / 10688346
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia6 / 9725061
normal139 / 336030741
ovarian tumor5 / 7668265
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain37 / 110098933
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye9 / 21105442
heart0 / 896260 
intestine3 / 23447212
kidney18 / 21177784
larynx0 / 241450 
liver2 / 2077439
lung35 / 336974103
lymph0 / 442700 
lymph node0 / 916100 
mammary gland5 / 15327132
mouth0 / 670520 
muscle5 / 10771546
nerve1 / 1576863
ovary5 / 10205148
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate14 / 18934573
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis14 / 33044242
thymus1 / 8113112
thyroid3 / 4747363
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus11 / 23287847
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205186_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.4
Adipocyte5.3
AdrenalCortex5.2
Adrenalgland4.35
Amygdala5.55
Appendix4.8
AtrioventricularNode3.9
BDCA4+_DentriticCells5
Bonemarrow5.05
BronchialEpithelialCells4.95
CD105+_Endothelial4.45
CD14+_Monocytes5.3
CD19+_BCells(neg._sel.)4.7
CD33+_Myeloid5.6
CD34+5.6
CD4+_Tcells5.05
CD56+_NKCells5.6
CD71+_EarlyErythroid4.5
CD8+_Tcells4.2
CardiacMyocytes6.45
Caudatenucleus5.3
Cerebellum4.1
CerebellumPeduncles5.8
CiliaryGanglion3.55
CingulateCortex5.9
Colorectaladenocarcinoma5.05
DorsalRootGanglion3.75
FetalThyroid4.8
Fetalbrain5.05
Fetalliver4.35
Fetallung7.55
GlobusPallidus3.75
Heart7.1
Hypothalamus9.25
Kidney4.3
Leukemia_chronicMyelogenousK-5624.55
Leukemia_promyelocytic-HL-604.45
Leukemialymphoblastic(MOLT-4)4
Liver7.75
Lung12.25
Lymphnode4.25
Lymphoma_burkitts(Daudi)6.6
Lymphoma_burkitts(Raji)7.1
MedullaOblongata4.3
OccipitalLobe4.5
OlfactoryBulb3.85
Ovary3.15
Pancreas3.9
PancreaticIslet15
ParietalLobe5.4
Pituitary11.85
Placenta5.75
Pons4.85
PrefrontalCortex7.7
Prostate6
Salivarygland3.8
SkeletalMuscle6.4
Skin3.65
SmoothMuscle5.25
Spinalcord13.75
SubthalamicNucleus4.4
SuperiorCervicalGanglion6.1
TemporalLobe4.6
Testis120.95
TestisGermCell193.5
TestisIntersitial225.75
TestisLeydigCell146.15
TestisSeminiferousTubule92.05
Thalamus5.15
Thymus3.95
Thyroid7
Tongue4.7
Tonsil6.05
Trachea9.6
TrigeminalGanglion4.65
Uterus4.15
UterusCorpus4.5
WholeBlood5.5
Wholebrain4.6
colon5.05
pineal_day6.22
pineal_night5.96
retina7.125
small_intestine4.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_2251_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.41 ± 0.53
Basal Forebrain4.38 ± 0.3
Basal Part of Pons3.86 ± 0.35
Cerebellar Cortex3.93 ± 0.53
Cerebellar Nuclei3.97 ± 0.66
Claustrum4.22 ± 0.75
Epithalamus5.87 ± 0.67
Frontal Lobe4.17 ± 0.66
Globus Pallidus4.95 ± 0.41
Hypothalamus4.66 ± 0.59
Insula4.26 ± 0.47
Limbic Lobe4.04 ± 0.57
Mesencephalon4.39 ± 0.53
Myelencephalon4.32 ± 0.62
Occipital Lobe4.35 ± 0.51
Parietal Lobe4.16 ± 0.45
Pontine Tegmentum4.14 ± 0.62
Striatum4.37 ± 0.85
Subthalamus3.82 ± 0.16
Temporal Lobe4.12 ± 0.48
Thalamus4.32 ± 0.41
White Matter4.53 ± 0.17
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dnali1CBCerebellum12.04
14.3
Dnali1CTXCerebral cortex0.9
0.88
Dnali1HIPHippocampal region2.66
3.46
Dnali1HPFHippocampal formation1.94
2.27
Dnali1HYHypothalamus0.11
0.16
Dnali1LSXLateral septal complex4.61
6.58
Dnali1MBMidbrain0.47
1.02
Dnali1MYMedulla2.59
3.35
Dnali1OLFOlfactory bulb1.61
1.23
Dnali1PPons0.26
0.52
Dnali1PALPallidum0.34
0.31
Dnali1RHPRetrohippocampal region0.88
0.86
Dnali1sAMYStriatum-like amygdalar nuclei0.16
0.11
Dnali1STRStriatum0.92
1.16
Dnali1STRdStriatum dorsal region0.52
0.65
Dnali1STRvStriatum ventral region0.62
0.54
Dnali1THThalamus1.89
3.34
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved